Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Xingxing Jian"'
Autor:
Lei Zhu, Xingxing Jian, Bingjing Zhou, Runqiu Liu, Melba Muñoz, Wan Sun, Lu Xie, Xiang Chen, Cong Peng, Marcus Maurer, Jie Li
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Chronic spontaneous urticaria (CSU) comes with gut dysbiosis, but its relevance remains elusive. Here we use metagenomics sequencing and short-chain fatty acids metabolomics and assess the effects of human CSU fecal microbial transplantation
Externí odkaz:
https://doaj.org/article/c2393565f8a6462c95084c292803ce5f
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1362-1371 (2023)
Although multiple vaccines have been developed and widely administered, several severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have been reported to evade immune responses and spread diffusely. Here, 108 RNA-seq files from coro
Externí odkaz:
https://doaj.org/article/29a8af2c999441b6bb04024bc173dd0f
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 29, Iss , Pp 285-295 (2022)
Neoantigen provides a promising breakthrough in tumor immunotherapy, although only a subset of patients responds well due to the quality of their immune response. However, few biomarkers have been reported to measure the quality of immune response to
Externí odkaz:
https://doaj.org/article/7e51ab696d7f4431b4147184dc96b705
iTCep: a deep learning framework for identification of T cell epitopes by harnessing fusion features
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Neoantigens recognized by cytotoxic T cells are effective targets for tumor-specific immune responses for personalized cancer immunotherapy. Quite a few neoantigen identification pipelines and computational strategies have been developed to improve t
Externí odkaz:
https://doaj.org/article/b614da1956ec4cfb93f6d42db579dd09
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5218-5225 (2022)
Transcriptomics studies have yielded great insights into disease processes by detecting differentially expressed genes (DEGs). In this study, due to the high heritability of Parkinson’s disease (PD), we performed bioinformatics analyses on nine tra
Externí odkaz:
https://doaj.org/article/cc463477b4d44aa4a8f4187ccf9e27ca
Autor:
Leliang Zheng, Ruizheng Sun, Yinghong Zhu, Zheng Li, Xiaoling She, Xingxing Jian, Fenglei Yu, Xueyu Deng, Buqing Sai, Lujuan Wang, Wen Zhou, Minghua Wu, Guiyuan Li, Jingqun Tang, Wei Jia, Juanjuan Xiang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Lung is colonized by a diverse array of microbes and the lung microbiota is profoundly involved in the development of respiratory diseases. There is little knowledge about the role of lung microbiota dysbiosis in lung cancer. In this study,
Externí odkaz:
https://doaj.org/article/a35db26d64f04a559d22532906d8f0e4
Publikováno v:
Cells, Vol 12, Iss 5, p 782 (2023)
The development of a neoantigen-based personalized vaccine has promise in the hunt for cancer immunotherapy. The challenge in neoantigen vaccine design is the need to rapidly and accurately identify, in patients, those neoantigens with vaccine potent
Externí odkaz:
https://doaj.org/article/5859d27522a24b9a9dd0b0d060629cad
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104190- (2022)
Summary: Patients with cancer with different molecular characterization and subtypes result in different response to anticancer therapeutics and survival. To identify features that are associated with prognosis is essential to precision medicine by p
Externí odkaz:
https://doaj.org/article/8e8aa15f5c9e42e6a7a6541049a4ae88
Autor:
Manman Lu, Linfeng Xu, Xingxing Jian, Xiaoxiu Tan, Jingjing Zhao, Zhenhao Liu, Yu Zhang, Chunyu Liu, Lanming Chen, Yong Lin, Lu Xie
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Neoantigens are widely reported to induce T-cell response and lead to tumor regression, indicating a promising potential to immunotherapy. Previously, we constructed an open-access database, i.e., dbPepNeo, providing a systematic resource for human t
Externí odkaz:
https://doaj.org/article/4a40ee39a88d409cb4e41496a57250ae
Autor:
Xingxing Jian, Yinghong Zhu, Jian Ouyang, Yihui Wang, Qian Lei, Jiliang Xia, Yongjun Guan, Jingyu Zhang, Jiaojiao Guo, Yanjuan He, Jinuo Wang, Jian Li, Jingchao Lin, Mingming Su, Guancheng Li, Minghua Wu, Lugui Qiu, Juanjuan Xiang, Lu Xie, Wei Jia, Wen Zhou
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-21 (2020)
Abstract Background Gut microbiome alterations are closely related to human health and linked to a variety of diseases. Although great efforts have been made to understand the risk factors for multiple myeloma (MM), little is known about the role of
Externí odkaz:
https://doaj.org/article/15421d00eee148178222fc528492688c