Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Xingxin Pan"'
Autor:
Meghan Collins, Ruggiero Gorgoglione, Valeria Impedovo, Xingxin Pan, Sathyaseelan Chakkarai, S. Stephen Yi, Alessia Lodi, Stefano Tiziani
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
Background and aimsAberrations in the immunoglobulin heavy chain (IgH) locus are associated with poor prognosis in pediatric precursor B-cell acute lymphoblastic leukemia (BCP-ALL) patients. The primary objective of this pilot study is to enhance our
Externí odkaz:
https://doaj.org/article/3be38ee58bba47608984c83aa621a49e
Autor:
Xingxin Pan, Jun Yun, Zeynep H. Coban Akdemir, Xiaoqian Jiang, Erxi Wu, Jason H. Huang, Nidhi Sahni, S. Stephen Yi
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 1533-1542 (2023)
Discovering effective therapies is difficult for neurological and developmental disorders in that disease progression is often associated with a complex and interactive mechanism. Over the past few decades, few drugs have been identified for treating
Externí odkaz:
https://doaj.org/article/20a864aabc5f4043b0ac3a7f59d4f919
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 3511-3521 (2022)
Effective and precise classification of glioma patients for their disease risks is critical to improving early diagnosis and patient survival. In the recent past, a significant amount of multi-omics data derived from cancer patients has emerged. Howe
Externí odkaz:
https://doaj.org/article/e31fa03c2a8d43c1ac702b2f9c856c22
Autor:
Chuang Zhang, Suolin Li, Chi Sun, Lin Liu, Yanbin Fang, Xiaofeng Yang, Xingxin Pan, Ben Zhang
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 24, Iss 12, Pp 1717-1725 (2021)
Objective(s): Vitexin, a natural flavonoid, is commonly found in many foods and traditional herbal medicines and has clear health benefits. However, the role of vitexin in cholestasis is presently unclear. This study investigated whether vitexin miti
Externí odkaz:
https://doaj.org/article/ac7b47b6d3964d5d95d609731140fd6c
Autor:
Xudong Liu, Zihui Zhao, Wufei Dai, Kuo Liao, Qi Sun, Dongjiang Chen, Xingxin Pan, Lishuang Feng, Ying Ding, Shiyou Wei
Publikováno v:
Cancers, Vol 15, Iss 17, p 4308 (2023)
Recurrent glioblastoma (rGBM) is a highly aggressive form of brain cancer that poses a significant challenge for treatment in neuro-oncology, and the survival status of patients after relapse usually means rapid deterioration, thus becoming the leadi
Externí odkaz:
https://doaj.org/article/6c1b6292746a4627931fae0576c7cb1b
Autor:
Alessia Lodi, Renu Pandey, Jennifer Chiou, Ayon Bhattacharya, Shiliang Huang, Xingxin Pan, Brandon Burgman, S. Stephen Yi, Stefano Tiziani, Andrew J. Brenner
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Glioblastomas (GBM) are the most common and aggressive form of primary malignant brain tumor in the adult population, and, despite modern therapies, patients often develop recurrent disease, and the disease remains incurable with median survival belo
Externí odkaz:
https://doaj.org/article/8d649ef526fa419aa6476b5269c3dcc0
Publikováno v:
Genes, Vol 10, Iss 10, p 778 (2019)
For cancer diagnosis, many DNA methylation markers have been identified. However, few studies have tried to identify DNA methylation markers to diagnose diverse cancer types simultaneously, i.e., pan-cancers. In this study, we tried to identify DNA m
Externí odkaz:
https://doaj.org/article/32e4ee1ca07e4722a37751b1dcd24d75
Publikováno v:
Genes, Vol 10, Iss 10, p 807 (2019)
Whole-genome bisulfite sequencing generates a comprehensive profiling of the gene methylation levels, but is limited by a high cost. Recent studies have partitioned the genes into landmark genes and target genes and suggested that the landmark gene e
Externí odkaz:
https://doaj.org/article/6015008e962249c58ced40e7762f2ab0
Autor:
Qing Kong, Shiyu Xia, Xingxin Pan, Kaixiong Ye, Zhouyihan Li, Haoyan Li, Xiaoqiang Tang, Nidhi Sahni, S. Stephen Yi, Xing Liu, Hao Wu, Michael B. Elowitz, Judy Lieberman, Zhibin Zhang
Publikováno v:
Science Immunology. 8
Granzyme A from killer lymphocytes cleaves gasdermin B (GSDMB) and triggers pyroptosis in targeted human tumor cells, eliciting antitumor immunity. However, GSDMB has a controversial role in pyroptosis and has been linked to both anti- and protumor f
Autor:
Xingxin Pan, Zeynep H Coban Akdemir, Ruixuan Gao, Xiaoqian Jiang, Gloria M Sheynkman, Erxi Wu, Jason H Huang, Nidhi Sahni, S Stephen Yi
Publikováno v:
Briefings in Bioinformatics. 24
Alzheimer’s disease (AD) is one of the most challenging neurodegenerative diseases because of its complicated and progressive mechanisms, and multiple risk factors. Increasing research evidence demonstrates that genetics may be a key factor respons