Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xingxian Gu"'
Autor:
Jianguang Zhou, Xingxian Gu, Shuping Yao, Jiong Ye, Peng Fu, Siqian Liu, Darija Dedic, Fabrice Gallou
Publikováno v:
Helvetica Chimica Acta. 106
Autor:
Yongbo Zhang, Xingmin Zhang, Jibin Zhao, Yingtao Tian, Xigui Jiang, Xingxian Gu, Xufan Wang, Mingxing Guan
Publikováno v:
Organic Process Research & Development. 25:1375-1382
Autor:
Alexandre Grand-Guillaume Perrenoud, Julien Haber, Florian Andreas Rampf, Van Tong Luu, Roger Humair, Wietfeld Bernhard, Michael Kibiger, Thomas Ruch, Lukas Padeste, Tao Hong, Pascal Beney, Yao Yang, Anikó Udvarhelyi, Leo A. Hardegger, Eric Sidler, Andreas Kaegi, Xingxian Gu, Dominique Bixel, Christian Fleury, Feng Gao, Thierry Schlama, Florian Kleinbeck
Publikováno v:
Organic Process Research & Development. 24:1763-1771
A process using an engineered phenylalanine ammonia lyase (PAL) enzyme was developed as part of an alternative route to a key intermediate of olodanrigan (EMA401). In the first part of this report,...
Autor:
Wietfeld Bernhard, Florian Kleinbeck, Jingjing Wu, Liqun Zhao, Francesco Venturoni, Weichun Liu, Xiangguang Tian, Gai Yu, Paolo Filipponi, Thomas Ruch, Nikola Kovacic, Bertrand Guelat, Philippe Piechon, Guanghua Jia, Xi Luo, Junjie Sun, Feng Gao, Xin Gu, Jianghua Zhang, Hai Dong, Thierry Schlama, Nadine Derrien, Thomas Allmendinger, Xiaoquan Lu, Bo Yu, Hongwei Yang, Huijuan Gu, Xuesong Zhang, Huaimin Wang, Yunzhong Li, Pascale Hoehn, Like Chen, Yingtao Tian, Su Xu, Luca Hermann, Berthold Schenkel, Shengqing Ye, Yan Wang, Xingxian Gu, Xufan Wang, Meng Chang, Min Zhongcheng, Jibin Zhao
Publikováno v:
The Journal of organic chemistry. 85(11)
LCZ696 is a novel treatment for patients suffering from heart failure that combines the two active pharmaceutical ingredients sacubitril and valsartan in a single chemical compound. While valsartan is an established drug substance, a new manufacturin
Autor:
Christopher J. Douglas, Zhuoran Zhang, Christopher J. Cramer, Lafe J. Purvis, Xingxian Gu, Soumen Ghosh
Publikováno v:
The Journal of Organic Chemistry. 83:1828-1841
Electron-deficient asymmetrically substituted diarylindenotetracenes were prepared via a series of Friedel-Crafts acylations, aryl-aryl cross-couplings, and an intramolecular oxidative cyclization to form the indene ring. Single-crystal X-ray experim
Autor:
Vijayalaxmi Gupta, Ernst Schönbrunn, Carolyn N. Kingsley, Joseph S. Tash, Xingxian Gu, Erick J. Carlson, Jon E. Hawkinson, Gunda I. Georg, Yan Yang, Jin-Yi Zhu
Publikováno v:
Chemmedchem
Analogues of N‐butyl‐1‐deoxynojirimycin (NB‐DNJ) were prepared and assayed for inhibition of ceramide‐specific glucosyltransferase (CGT), non‐lysosomal β‐glucosidase 2 (GBA2) and the lysosomal β‐glucosidase 1 (GBA1). Compounds 5 a
Autor:
Mingxing Guan, Yingtao Tian, Jibin Zhao, Xingxian Gu, Xigui Jiang, Xufan Wang, Yongbo Zhang, Xingmin Zhang
Publikováno v:
Organic Process Research & Development; 6/18/2021, Vol. 25 Issue 6, p1375-1382, 8p
Autor:
Xingxian Gu, Gunda I. Georg
Publikováno v:
Tetrahedron Letters. 56(43):5874-5877
Reactions of N-alkyl-2,3-dihydro-4-pyridones and 4-(pyrrolidin-1-yl)furan-2(5H)-one with aldehydes and triethylsilane in a one-flask procedure provided C5 and C3 alkylated derivatives, respectively. Mannich-type reactions with formaldehyde and carbam
Autor:
Xingxian Gu, Gunda I. Georg
Publikováno v:
ChemInform. 47
Reactions of N-alkyl-2,3-dihydro-4-pyridones and 4-(pyrrolidin-1-yl)furan-2(5H)-one with aldehydes and triethylsilane in a one-flask procedure provided C5 and C3 alkylated derivatives, respectively. Mannich-type reactions with formaldehyde and carbam
Autor:
Xingxian Gu, Gunda I. Georg
Publikováno v:
ChemInform. 45
Lithium perchlorate and acetic anhydride were the key additives for the multi-component reaction between 3-aminocyclohex-2-enones, formaldehyde, and malonates yielding adducts that were annulated under acidic conditions to afford bicyclic 2,5-dioxooc