Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Xingte Chen"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundHepatocellular carcinoma (HCC) poses a significant global health challenge due to its poor prognosis and limited therapeutic modalities. Anoikis and ErbB signaling pathways are pivotal in cancer cell proliferation and metastasis, but their
Externí odkaz:
https://doaj.org/article/5dd664616cdd47f4888570c106d88afd
Autor:
Yaqi Zhong, Xingte Chen, Shiji Wu, Huipeng Fang, Liang Hong, Lingdong Shao, Lei Wang, Junxin Wu
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundRadiotherapy (RT) is a critical component of treatment for locally advanced rectal cancer (LARC), though patient response varies significantly. The variability in treatment outcomes is partly due to the resistance conferred by cancer stem c
Externí odkaz:
https://doaj.org/article/90843e0c817348cebab9de67267f8439
Autor:
Lei Wang, Han Zhou, Qingjing Chen, Zhiwen Lin, Chenwei Jiang, Xingte Chen, Mingdong Chen, Libin Liu, Lingdong Shao, Xiaolong Liu, Jianji Pan, Jingcheng Wu, Jibin Song, Junxin Wu, Da Zhang
Publikováno v:
Advanced Science, Vol 11, Iss 7, Pp n/a-n/a (2024)
Abstract Hypoxia‐associated radioresistance in rectal cancer (RC) has severely hampered the response to radioimmunotherapy (iRT), necessitating innovative strategies to enhance RC radiosensitivity and improve iRT efficacy. Here, a catalytic radiose
Externí odkaz:
https://doaj.org/article/bde182803de1489bbb554434e6a66a42
Autor:
Lei Wang, Kai Wang, Jinluan Li, Junxin Wu, Libin Liu, Da Zhang, Jianji Pan, Han Zhou, Zhiwen Lin, Chenwei Jiang, Xingte Chen, Lingdong Shao
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Preoperative radiation therapy (preRT) is a fundamental aspect of neoadjuvant treatment for rectal cancer (RC), but the response to this treatment remains unsatisfactory. The combination of radiation therapy (RT) and immunotherapy (iRT) pr
Externí odkaz:
https://doaj.org/article/1548aebb1fb74763b5c983dd478e3e7b
Autor:
Lei Wang, Xingte Chen, Hejun Zhang, Liang Hong, Jianchao Wang, Lingdong Shao, Gang Chen, Junxin Wu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundTransient receptor potential channels (TRPC) play critical regulatory functions in cancer occurrence and progression. However, knowledge on its role in colorectal cancer (CRC) is limited. In addition, neoadjuvant treatment and immune checkp
Externí odkaz:
https://doaj.org/article/d7f1862f28c2456d975c5be76a999b00
Autor:
Xingte Chen, Lei Wang, Liang Hong, Zhixiong Su, Xiaohong Zhong, Han Zhou, Xueqing Zhang, Junxin Wu, Lingdong Shao
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Background: Aging is a well-studied concept, but no studies have comprehensively analyzed the association between aging-related genes (AGs) and hepatocellular carcinoma (HCC) prognosis.Methods: Gene candidates were selected from differentially expres
Externí odkaz:
https://doaj.org/article/a0b7d1ee1a284a3689d0e87108727f6b
Publikováno v:
Hepatobiliary Surg Nutr
BACKGROUND: Hepatocellular carcinoma (HCC) is one of the most common causes of cancer worldwide. Although many studies have focused on oncogene characteristics, the genomic landscape of Chinese HCC patients has not been fully clarified. METHODS: A to
Autor:
Junxin Wu, Gang Chen, Zhixiong Su, Lei Wang, Xingte Chen, Xiaohong Zhong, Di Wang, Jianchao Wang, Lingdong Shao
Publikováno v:
Combinatorial chemistryhigh throughput screening. 25(12)
Background: Tumorigenesis, metastasis, and treatment response of hepatocellular carcinoma (HCC) are regulated by unfolded protein responses (UPR) signaling pathways, including IRE1a, PERK, and ATF6, but little is known about UPR related genes with HC
Publikováno v:
International Immunopharmacology. 109:108866
Chromatin organization is associated with tumorigenesis; however, information on its role in hepatocellular carcinoma (HCC) is limited. Moreover, although immune checkpoint inhibitors (ICIs) have proven effective against HCC, the optimal index remain
Publikováno v:
SSRN Electronic Journal.