Single-cell sequencing reveals the heterogeneity of B cells and tertiary lymphoid structures in muscle-invasive bladder cancer

Autor: Hao Yuan, Xingning Mao, Yunkun Yan, Rong Huang, Qingyun Zhang, Yanyu Zeng, Mengying Bao, Yan Dai, Bo Fang, Junhao Mi, Yuli Xie, Xiang Wang, Haiying Zhang, Zengnan Mo, Rirong Yang

Publikováno v: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-17 (2024)

Abstract Background Muscle-invasive bladder cancer (MIBC) is a highly aggressive disease with a poor prognosis. B cells are crucial factors in tumor suppression, and tertiary lymphoid structures (TLSs) facilitate immune cell recruitment to the tumor

Externí odkaz: https://doaj.org/article/aecfb80697464b68a47ac73b14b8b5c7

A spatiotemporal steroidogenic regulatory network in human fetal adrenal glands and gonads

Autor: Yifu Wang, Bingqian Guo, Yajie Guo, Nana Qi, Yufang Lv, Yu Ye, Yan Huang, Xinyang Long, Hongfei Chen, Cheng Su, Liying Zhang, Qingyun Zhang, Minxi Li, Jinling Liao, Yunkun Yan, Xingning Mao, Yanyu Zeng, Jinghang Jiang, Zhongyuan Chen, Yi Guo, Shuai Gao, Jiwen Cheng, Yonghua Jiang, Zengnan Mo

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Human fetal adrenal glands produce substantial amounts of dehydroepiandrosterone (DHEA), which is one of the most important precursors of sex hormones. However, the underlying biological mechanism remains largely unknown. Herein, we sequenced human f

Externí odkaz: https://doaj.org/article/0e0510f9844748a39f0c254d7e1c2422

Association of UCP1 polymorphisms with type 2 diabetes mellitus and their interaction with physical activity and sedentary behavior

Autor: Haisheng Yang, Xingning Mao, Qiuyu Fan, Lianguang Xie, Haiying Zhang, Xiaolang Chen, Lulin Chen, Lulu Zhang, Yingnan Lv, Chunting Dong, Tianzhu Long, Rongqing Yang

Publikováno v: Gene. 739

Uncoupling protein 1 (UCP1) has been reported to be associated with type 2 diabetes mellitus (T2DM) in different populations, however, little is reported in Chinese population. The present study aimed to explore the association between some polymorph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b7aa937d275595499987159524d98d0
https://pubmed.ncbi.nlm.nih.gov/32088243

Single-cell sequencing reveals the heterogeneity of B cells and tertiary lymphoid structures in muscle-invasive bladder cancer.

Autor: Yuan, Hao^1,2 (AUTHOR), Mao, Xingning^1,3,4 (AUTHOR), Yan, Yunkun¹ (AUTHOR), Huang, Rong^1,2 (AUTHOR), Zhang, Qingyun⁵ (AUTHOR), Zeng, Yanyu¹ (AUTHOR), Bao, Mengying¹ (AUTHOR), Dai, Yan¹ (AUTHOR), Fang, Bo¹ (AUTHOR), Mi, Junhao¹ (AUTHOR), Xie, Yuli^1,2 (AUTHOR), Wang, Xiang^1,2 (AUTHOR), Zhang, Haiying^1,3,4,6 (AUTHOR) zhanghaiying@gxmu.edu.cn, Mo, Zengnan^1,7 (AUTHOR) mozengnan@gxmu.edu.cn, Yang, Rirong^1,2 (AUTHOR) yangrirong@sr.gxmu.edu.cn

Publikováno v: Journal of Translational Medicine. 1/12/2024, Vol. 22 Issue 1, p1-17. 17p.

Establishment of a risk score model for bladder urothelial carcinoma based on energy metabolism‐related genes and their relationships with immune infiltration.

Autor: Huang, Caihong, Li, Yexin, Ling, Qiang, Wei, Chunmeng, Fang, Bo, Mao, Xingning, Yang, Rirong, Zhang, LuLu, Huang, Shengzhu, Cheng, Jiwen, Liao, Naikai, Wang, Fubo, Mo, Linjian, Mo, Zengnan, Li, Longman

Publikováno v: FEBS Open Bio; Apr2023, Vol. 13 Issue 4, p736-750, 15p