Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Xingming, Shi"'
Autor:
Yun Su, Xing Chen, Hongyan Zhou, Sean Shaw, Jie Chen, Carlos M. Isales, Jing Zhao, Xingming Shi
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive agents. However, their clinical usage is limited by severe multisystemic side effects. Glucocorticoid induced osteoporosis results in significant morbidity and mortality but the
Externí odkaz:
https://doaj.org/article/93b25f4035294b2d9375678db8f1351d
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The plasticity and proliferative capacity of stem cells decrease with aging, compromising their tissue regenerative potential and therapeutic applications. This decline is directly linked to mitochondrial dysfunction. Here, we present an eff
Externí odkaz:
https://doaj.org/article/6712ff8964f54ec9829463fbffb61606
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Uterine leiomyoma (UL), common benign tumors in women of child-bearing age, are believed to be caused mainly by Qi stagnation and blood stasis, according to a theory of traditional Chinese medicine. Curcumae Rhizoma and Sparganii Rhizoma (CRSR) is a
Externí odkaz:
https://doaj.org/article/010cea99dab844acb48b94a6d66dde5b
Autor:
Yewen Feng, Yumin Zhao, Yao Li, Teng Peng, Yu Kuang, Xingming Shi, Gang Wang, Fu Peng, Chenghao Yu
Publikováno v:
Frontiers in Public Health, Vol 9 (2021)
Background: The herbs Rhizoma Curcumae and Rhizoma Sparganii (RCRS) are often used in traditional Chinese medicine for the treatment of uterine leiomyoma (UL). The effectiveness of RCRS for the treatment of UL has been confirmed in our previous studi
Externí odkaz:
https://doaj.org/article/1722293d637e4c5db020b1334add95a4
Autor:
Kanglun Yu, Anuj K. Sharma, Carlos M. Isales, Rachel L. Roberts, Jessica L. Pierce, Debra L. Irsik, Reginald D. Benson, Meghan E. McGee-Lawrence, Helen Kaiser, Mark W. Hamrick, Wendy B. Bollag, Vivek Choudhary, Chase J. Wehrle, Maribeth H. Johnson, Husam Bensreti, Andrew Khayrullin, Jennifer S. Dorn, Colleen Davis, Xingming Shi
Publikováno v:
J Bone Miner Res
Hallmarks of aging-associated osteoporosis include bone loss, bone marrow adipose tissue (BMAT) expansion, and impaired osteoblast function. Endogenous glucocorticoid levels increase with age, and elevated glucocorticoid signaling, associated with ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc8b2e871d2949498ba00ffbee36e89
https://doi.org/10.1002/jbmr.4468
https://doi.org/10.1002/jbmr.4468
Publikováno v:
J Nutr
BACKGROUND: Bone marrow osteoblasts and adipocytes are derived from a common mesenchymal stem cell and have a reciprocal relationship. Peroxisome proliferator-activated receptor gamma (PPARγ), a regulator for adipocyte differentiation, may be a pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134d821124e618b7d144ccf986fcfbaf
https://doi.org/10.1093/jn/nxab173
https://doi.org/10.1093/jn/nxab173
Autor:
Guodong Pan, Meghan E McGee Lawrence, Jianru Xu, Hongyan Zhou, Yonggang Bao, Jay Cao, Mark W. Hamrick, Xingming Shi, Kehong Ding, Carlos M Isales, Raysa Rosario, Yun Su
Publikováno v:
J Gerontol A Biol Sci Med Sci
Bone loss in aging is linked with chronic low-grade inflammation and the accumulation of marrowfat in animals and humans. Peroxisome proliferator-activated receptor gamma (PPARγ), an adipogenic regulator, plays key roles in these biological processe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e7e1406e63ead59ae995257cf28af37
https://doi.org/10.1093/gerona/glaa049
https://doi.org/10.1093/gerona/glaa049
Autor:
Colleen Davis, Carlos M. Isales, Vivek Choudhary, Chase J. Wehrle, Jessica L. Pierce, Kanglun Yu, Maribeth H. Johnson, Jennifer S. Dorn, Reginald D. Benson, Andrew Khayrullin, Meghan E. McGee-Lawrence, Anuj K. Sharma, Xingming Shi, Wendy B. Bollag, Husam Bensreti, Rachel L. Roberts, Mark W. Hamrick, Helen Kaiser, Debra L. Irsik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::02f6b9725b6487bf217924bfe52fc5bd
https://doi.org/10.1002/jbmr.4468/v2/response1
https://doi.org/10.1002/jbmr.4468/v2/response1
Publikováno v:
Curr Dev Nutr
OBJECTIVES: Obesity is detrimental to bone health in humans and in high-fat diet-induced obese animals. Bone marrow osteoblasts and adipocytes are derived from a common mesenchymal stem cell and have a reciprocal relationship. Peroxisome proliferator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47c2a5660d1b7cc488c0d9bc723a2c10
https://europepmc.org/articles/PMC8180769/
https://europepmc.org/articles/PMC8180769/
Publikováno v:
Current Osteoporosis Reports. 17:438-445
The development of adiposity in the bone marrow, known as marrow adipose tissue (MAT), is often associated with musculoskeletal frailty. Glucocorticoids, which are a key component of the biological response to stress, affect both bone and MAT. These
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d81df6bfb5d83861354d69d65f16c3c8
https://doi.org/10.1007/s11914-019-00554-6
https://doi.org/10.1007/s11914-019-00554-6