Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Xingliang Nie"'
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Sulfonyl fluorides are compounds with potential application in chemical biology and drug discovery, but their preparation can be challenging. Here, the authors present a type of bench-stable fluorosulfonyl radical reagents that enable radical fluoros
Externí odkaz:
https://doaj.org/article/32b1ae80f72a4c1faff125f694b0fc31
Publikováno v:
Organic Chemistry Frontiers. 9:4854-4860
SO2 radical insertion/fluorination via a photocatalytic redox strategy is developed, providing an efficient and reliable approach for the synthesis of alkylsulfonyl fluorides.
Autor:
Xingliang Nie, Saihu Liao
Publikováno v:
Synlett. 33:401-408
Sulfonyl fluorides have widespread applications in many fields. In particular, the increasing research interest on the study of sulfonyl fluorides in the context of chemical biology and drug discovery in the past decade has raised a high demand for n
Publikováno v:
Angewandte Chemie International Edition. 60:22035-22042
Sulfonyl fluorides have widespread applications in many important fields, including ligation chemistry, chemical biology, and drug discovery. Therefore, new methods to increase the synthetic efficiency and expand the available structures of sulfonyl
Autor:
Yong Chen, Jinshuai Song, Anandkumar Devaraj, Tianxiao Xu, Saihu Liao, Bolun Zhang, Xingliang Nie
Publikováno v:
Angewandte Chemie International Edition. 60:3956-3960
Sulfonyl fluorides have widespread applications in many fields. In particular, their unique biological activity has drawn considerable research interest in the context of chemical biology and drug discovery in the past years. Therefore, new and effic
Autor:
Peng Wang, Honghai Zhang, Mingqi Zhao, Shuangshuang Ji, Lu Lin, Na Yang, Xingliang Nie, Jinshuai Song, Saihu Liao
Publikováno v:
Angewandte Chemie (International ed. in English). 61(39)
Recently, radical fluorosulfonylation is emerging as an appealing approach for the synthesis of sulfonyl fluorides, which are highly in demand in various disciplines, particularly in chemical biology and drug discovery. Here, we report the first esta
Autor:
Xingliang Nie, Lin Huang, Zhang Yingyin, Saihu Liao, Qingyuan Feng, Dengfeng Chen, Qiuyue Wang, Yiheng Wang, Shenlin Huang
Publikováno v:
Angewandte Chemie (International ed. in English). 60(52)
Radical fluorosulfonylation is emerging as an appealing approach for the synthesis of sulfonyl fluorides, which have widespread applications in many fields, in particular in the context of chemical biology and drug development. Here, we report the fi
Publikováno v:
Organic letters. 22(9)
Thioesters and related thiols are critically important to biological systems and also widely employed in the synthesis of pharmaceutically important molecules and polymeric materials. However, known synthetic methods often suffer from the disadvantag
Publikováno v:
Tetrahedron Letters. 57:2331-2335
A straightforward, efficient, and highly diastereoselective method for the synthesis of 3,4-cyclopenta-1-tetralones has been realized via the copper-catalyzed coupling of 2-vinyl benzaldehydes with 3-alkenyl 2-bromocarbonyls. Subsequent reduction wit
Publikováno v:
Angewandte Chemie (International ed. in English). 56(7)
A palladium-catalyzed three-component reaction between fluoroalkyl bromides, arylboronic acids, and alkenyl aldehydes has been developed and provides facile access to 5-, 6-, or 7-difluoroalkylated ketones under very mild reaction conditions. The res