Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xinghui Si"'
Autor:
Haochen Yao, Sheng Ma, Juanjuan Huang, Xinghui Si, Ming Yang, Wantong Song, Guoyue Lv, Guoqing Wang
Publikováno v:
Advanced Science, Vol 11, Iss 44, Pp n/a-n/a (2024)
Abstract Reversing the hepatic inflammatory and immunosuppressive microenvironment caused by gut microbiota‐derived lipopolysaccharides (LPS), accumulating to the liver through the gut‐liver axis, is crucial for suppressing hepatocellular carcino
Externí odkaz:
https://doaj.org/article/77ed13ea08cb43fd86f4092c8206461e
Autor:
Xinghui Si, Guofeng Ji, Sheng Ma, Zichao Huang, Taiyuan Liu, Zhiyuan Shi, Yu Zhang, Jia Li, Wantong Song, Xuesi Chen
Publikováno v:
Advanced Science, Vol 11, Iss 38, Pp n/a-n/a (2024)
Abstract Local immunotherapy represents a promising solution for preventing tumor recurrence and metastasis post tumor surgical resection by eliminating residue tumor cells as well as eliciting tumor‐specific immune responses. Minimally invasive su
Externí odkaz:
https://doaj.org/article/8c53c6c75b1d4946a722d306c93ee26e
Autor:
Bo Yang, Zhaohui Tang, Xuedong Fang, Yajun Xu, Wantong Song, Xinghui Si, Guofeng Ji, Mingqiang Li, Leaf Huang, Xuesi Chen, Si Dong
Publikováno v:
Nano Letters. 21:6781-6791
Gut bacteria and their metabolites influence the immune microenvironment of liver through the gut-liver axis, thus representing emerging therapeutic targets for liver cancer therapy. However, directly manipulating gut microbiota or their metabolites
Autor:
Sheng Ma, Zhaohui Tang, Y.P. Xu, Yu Zhang, Xinghui Si, Wantong Song, Xuesi Chen, Jiayu Zhao, Zichao Huang
Publikováno v:
Nano Research. 15:1183-1192
Certain chemo drugs have been reported to potentially induce tumor-specific immune recognition by triggering immunogenic cell death (ICD), which provides a promising alternative way for cancer immunotherapy. However, the immunogenic effects of such t
Autor:
Xinghui Si, Guofeng Ji, Sheng Ma, Hongyu Chen, Zhiyuan Shi, Yu Zhang, Zhaohui Tang, Wantong Song, Xuesi Chen
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 353
Immunotherapy has been widely used in the treatment of advanced stage cancers with spreading metastases, while the fully activation of immune system often requires sustained and long-acting immune stimulation by immunotherapeutic agents. In previous
Publikováno v:
CCS Chemistry. 2:390-400
Tumor-promoting inflammation is accompanied by cancer initiation, progression, and metastasis. Cyclooxygenase-2 (COX-2) and its downstream product, prostaglandin E2 (PGE2), play critical roles in t...
Autor:
Wantong Song, Xinghui Si, Lushun Ma, Fangfang Chen, Sheng Ma, Xin Bao, Lili Ma, Leaf Huang, Haochen Yao, Chong Ma, Xuedong Fang, Guofeng Ji, Yalin Wang
Publikováno v:
Acta Pharmaceutica Sinica B. 10:2171-2182
Primary bile acids were reported to augment secretion of chemokine (C‒X‒C motif) ligand 16 (CXCL16) from liver sinusoidal endothelial cells (LSECs) and trigger natural killer T (NKT) cell-based immunotherapy for liver cancer. However, abundant ex
Autor:
Yudi Xu, Sheng Ma, Jiayu Zhao, Hongyu Chen, Xinghui Si, Zichao Huang, Zhentao Yu, Wantong Song, Zhaohui Tang, Xuesi Chen
Publikováno v:
Biomaterials. 284
Using nanotechnology for cancer vaccine design holds great promise because of the intrinsic feature of nanoparticles in being captured by antigen-presenting cells (APCs). However, there are still obstacles in current nanovaccine systems in achieving
Autor:
Zhaohui Tang, Y.P. Xu, Xuedong Fang, Xuesi Chen, Wantong Song, Guofeng Ji, Jiayu Zhao, Xinghui Si, Zhentao Yu, Haochen Yao, Si Dong
Publikováno v:
Biomaterials science. 9(20)
Cancer vaccines artificially stimulate the immune system against cancer and are considered the most promising treatment of cancer. However, the current progress in vaccine research against cancer is still limited and slow, partially due to the diffic
Publikováno v:
Science China Materials. 63:307-315
The key to improve the therapeutic efficacy for cancer treatment is to increase the delivery of drugs to tumors. For this purpose, tumor-microenvironment stimuli- responsive materials have great potential. Here, we prepared a new nanomedicine by bond