Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Xinghao Yu"'
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background To study the shared genetic structure between autoimmune diseases and B-cell acute lymphoblastic leukemia (B-ALL) and identify the shared risk loci and genes and genetic mechanisms involved. Methods Based on large-scale genome-wid
Externí odkaz:
https://doaj.org/article/b856788dcd1e48d496e1f445a3c6e119
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionClinical observations have found that prolonged use of analgesics increases the incidence of infection. However, the direct causal relationship between prescription analgesic use (PAU) and risk of infection (ROI) remains unclear.MethodsTh
Externí odkaz:
https://doaj.org/article/2f9aed33f93c498a8345507faa00ad04
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Genomics involving tens of thousands of genes is a complex system determining phenotype. An interesting and vital issue is how to integrate highly sparse genetic genomics data with a mass of minor effects into a prediction model for improving predict
Externí odkaz:
https://doaj.org/article/a42f04278ef54d54a867570957cc43d3
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
The correlation between autophagy defects and oral squamous cell carcinoma (OSCC) has been previously studied, but only based on a limited number of autophagy-related genes in cell lines or animal models. The aim of the present study was to analyze d
Externí odkaz:
https://doaj.org/article/71711f269a7047679aa829b4d01213c8
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
BackgroundPrevious cancer prognostic prediction models often consider only the most important transcriptomic expressions, and their power is limited. It is unknown whether prediction power can be further improved when additional transcriptomic inform
Externí odkaz:
https://doaj.org/article/f14612c9044e46c49626cd7fc95a3570
Autor:
Ting Wang, Zaixiang Tang, Xinghao Yu, Yixing Gao, Fengjun Guan, Chengzong Li, Shuiping Huang, Junnian Zheng, Ping Zeng
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
ObjectivePrior studies have shown that there is an inverse association between birth weight and stroke in adulthood; however, whether such association is causal remains yet known and those studies cannot distinguish between the direct fetal effect an
Externí odkaz:
https://doaj.org/article/03106cfca3f642dd8f75805559121637
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Purpose: Inverse association between premorbid body mass index (BMI) and amyotrophic lateral sclerosis (ALS) was implied in observational studies; however, whether this association is causal remains largely unknown.Materials and Methods: We first con
Externí odkaz:
https://doaj.org/article/fca6dde094704442989b37568432d1e5
Autor:
Lin Zhang, Changfu Hao, Juan Li, Yaqian Qu, Lei Bao, Yiping Li, Zhongzheng Yue, Miao Zhang, Xinghao Yu, Huiting Chen, Jianhui Zhang, Di Wang, Wu Yao
Publikováno v:
Tumor Biology, Vol 39 (2017)
The incidence of disease relating to nanoparticle exposure has been rising rapidly in recent years, for which there is no effective treatment. Macrophage is suggested to play a crucial role in the development of pulmonary disease. To investigate the
Externí odkaz:
https://doaj.org/article/c766b8167f774a77a561e96fec8e1037
Publikováno v:
Osteoarthritis and Cartilage. 29:1741-1750
Summary Objective There is considerable evidence for relationship between gut microbiota and osteoarthritis (OA), but no studies have investigated their causal relationship. Method This study utilized large-scale genome-wide association studies (GWAS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58232904615e77f50dc08d89c0a21633
https://doi.org/10.1016/j.joca.2021.08.003
https://doi.org/10.1016/j.joca.2021.08.003
Publikováno v:
Human Molecular Genetics. 31:604-613
Observational studies provide evidence that metabolites may be involved in the development of autoimmune diseases (ADs), but whether it is causal is still unknown. Based on the large-scale genome-wide association studies (GWAS) summary statistics, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026501af00c0423aa13c904e51609522
https://doi.org/10.1093/hmg/ddab273
https://doi.org/10.1093/hmg/ddab273