Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Xingguo Zhu"'
Autor:
Jian Feng, Yuanzhen Ren, Xilin Wang, Xiaojing Li, Xingguo Zhu, Baokai Zhang, Qi Zhao, Xiaochen Sun, Xinxin Tian, Hongyang Liu, Fan Dong, Xiu-Li Li, Linlin Qi, Bin Wei
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Previous studies have demonstrated an association between lymphatic vessels and diseases caused by bacterial infections. Listeria monocytogenes (LM) bacterial infection can affect multiple organs, including the intestine, brain, liver and spleen, whi
Externí odkaz:
https://doaj.org/article/b6062cc00c4e4f24b5ef0ec5f5ed6261
Autor:
Caixia Xi, Chithra Palani, Mayuko Takezaki, Huidong Shi, Anatolij Horuzsko, Betty S. Pace, Xingguo Zhu
Publikováno v:
Antioxidants, Vol 13, Iss 3, p 337 (2024)
Sickle cell disease (SCD) is a pathophysiological condition of chronic hemolysis, oxidative stress, and elevated inflammation. The transcription factor Nrf2 is a master regulator of oxidative stress. Here, we report that the FDA-approved oral agent s
Externí odkaz:
https://doaj.org/article/c1910e2fb1794767b5f95b3b50efbd6c
Autor:
Ashwin Ajith, Kenza Mamouni, Daniel D. Horuzsko, Abu Musa, Amiran K. Dzutsev, Jennifer R. Fang, Ahmed Chadli, Xingguo Zhu, Iryna Lebedyeva, Giorgio Trinchieri, Anatolij Horuzsko
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
The triggering receptor expressed on myeloid cell 1 (TREM1) plays a critical role in development of chronic inflammatory disorders and the inflamed tumor microenvironment (TME) associated with most solid tumors. We examined whether loss of TREM1 sign
Externí odkaz:
https://doaj.org/article/5bb71203ab174a6d97240f62410448ca
Autor:
Fang Zhang, Baokai Zhang, Huihua Ding, Xiangyue Li, Xilin Wang, Xiaomin Zhang, Qiaojie Liu, Qiuyun Feng, Mingshun Han, Longlong Chen, Linlin Qi, Dan Yang, Xiaojing Li, Xingguo Zhu, Qi Zhao, Jiaqian Qiu, Zhengjiang Zhu, Huiru Tang, Nan Shen, Hongyan Wang, Bin Wei
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Systemic lupus erythematosus (SLE) is a complex autoimmune disease with abnormal activation of the immune system. Recent attention is increasing about how aberrant lipid and cholesterol metabolism is linked together with type I interferon (I
Externí odkaz:
https://doaj.org/article/ab3d615e274a4b65a045a2e56d0ab463
Autor:
Linlin Qi, Xiaojing Li, Fang Zhang, Xingguo Zhu, Qi Zhao, Dan Yang, Shujie Hao, Tong Li, Xiangyue Li, Taikun Tian, Jian Feng, Xiaochen Sun, Xilin Wang, Shangyan Gao, Hanzhong Wang, Jing Ye, Shengbo Cao, Yulong He, Hongyan Wang, Bin Wei
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112489- (2023)
Summary: Upon recognizing danger signals produced by virally infected neurons, macrophages in the central nervous system (CNS) secrete multiple inflammatory cytokines to accelerate neuron apoptosis. The understanding is limited about which key effect
Externí odkaz:
https://doaj.org/article/9b699b87a8064568a34d1937e6ff50ef
Autor:
Yingying Gou, Dan Yang, Taikun Tian, Xingguo Zhu, Raorao Zhang, Jiaqi Ren, Dezhen Tu, Yi Luo, Yuqing Miao, Huan Zhao, Yu Wang, Bin Wei
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Hepatocellular carcinoma (HCC) is one of the most common digestive system cancers (DSCs) with a poor prognosis. Zinc‐regulated transporter (ZRT)/iron‐regulated transporter (IRT) like protein transporters (ZIPs) encode membrane transport proteins,
Externí odkaz:
https://doaj.org/article/bbff9c0c61454e0b96e19be87405039a
Publikováno v:
Epigenetics, Vol 12, Iss 3, Pp 226-237 (2017)
LTR retrotransposons are repetitive DNA elements comprising ∼10% of the human genome. They are silenced by hypermethylation of cytosines in CpG dinucleotides and are considered parasitic DNA serving no useful function for the host genome. However,
Externí odkaz:
https://doaj.org/article/7e034bc4ffc64ae28ea805f1f68cc5da
Autor:
Biaoru Li, Xingguo Zhu, Mir A. Hossain, Cameron R. Guy, Hongyan Xu, Jörg Bungert, Betty S. Pace
Publikováno v:
Haematologica, Vol 103, Iss 9 (2018)
Externí odkaz:
https://doaj.org/article/c8f66fcd67de43eca65d83bbd402cbbe
Autor:
Xingguo Zhu, Tianxiang Hu, Meng Hsuan Ho, Yongchao Wang, Miao Yu, Niren Patel, Wenhu Pi, Jeong-Hyeon Choi, Hongyan Xu, Vadivel Ganapathy, Ferdane Kutlar, Abdullah Kutlar, Dorothy Tuan
Publikováno v:
Haematologica, Vol 102, Iss 12 (2017)
Hydroxyurea (HU), the first of two drugs approved by the US Food and Drug Administration for treating patients with sickle cell disease (SCD), produces anti-sickling effect by re-activating fetal γ-globin gene to enhance production of fetal hemoglob
Externí odkaz:
https://doaj.org/article/53eaa618682545f998578fcfc3dd9fdc
NRF2 mediates γ-globin gene regulation and fetal hemoglobin induction in human erythroid progenitors
Publikováno v:
Haematologica, Vol 102, Iss 8 (2017)
Externí odkaz:
https://doaj.org/article/90e430f2b59e487dade47c6833a1c776