Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xingguang Liang"'
Autor:
Juan Du, Junlei Zhang, Lin Wang, Xun Wang, Yaxing Zhao, Jiaoying Lu, Tingmin Fan, Meng Niu, Jie Zhang, Fei Cheng, Jun Li, Qi Zhu, Daoqiang Zhang, Hao Pei, Guang Li, Xingguang Liang, He Huang, Xiaocang Cao, Xinjuan Liu, Wei Shao, Jianpeng Sheng
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Ulcerative colitis is a chronic inflammatory bowel disorder with cellular heterogeneity. To understand the composition and spatial changes of the ulcerative colitis ecosystem, here we use imaging mass cytometry and single-cell RNA sequencing
Externí odkaz:
https://doaj.org/article/e3dcdf2b05c141f9b0e478721e87034b
Autor:
Jinghua Jin, Zhi Xu, Lina Zhang, Can Zhang, Xiaoduo Zhao, Yuxuan Mao, Haojian Zhang, Xingguang Liang, Juanli Wu, Ying Yang, Jing Zhang
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTPeripheral β-amyloid (Aβ), including those contained in the gut, may contribute to the formation of Aβ plaques in the brain, and gut microbiota appears to exert an impact on Alzheimer’s disease (AD) via the gut-brain axis, although detai
Externí odkaz:
https://doaj.org/article/8e37d52d89a84e2f8402b4d5b8d7f65d
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 20, Iss 11, Pp 1207-1212 (2017)
Objective(s): Arachidonic Acid/5-lipoxygenase (AA/5-LOX) pathway connects lipid metabolism and proinflammatory cytokine, which are both related to the development and progression of nonalcoholic fatty liver disease (NAFLD). Therefore, the present stu
Externí odkaz:
https://doaj.org/article/063f2e2745dc4ead9c813d7eaec89ac0
Autor:
Rongrong Tao, Meihua Liao, Yuxiang Wang, Huan Wang, Yuhang Tan, Siyao Qin, Wenjing Wei, Chunzhi Tang, Xingguang Liang, Yifeng Han, Xin Li
Publikováno v:
Analytical Chemistry. 94:1308-1317
Alterations in formaldehyde (FA) homeostasis are associated with the pathology of Alzheimer's disease (AD). In vivo tracking of FA flux is important for understanding the underlying molecular mechanisms, but is challenging due to the lack of sensitiv
Publikováno v:
Industrial & Engineering Chemistry Research. 60:14341-14353
Publikováno v:
The Journal of Toxicological Sciences. 46:273-282
Quantum dots (QDs) are new types of fluorescent nanomaterials which can be utilized as ideal agents for intracellular tracking, drug delivery, biomedical imaging and diagnosis. It is urgent to understand their potential toxicity and the interactions
Autor:
En Chen, Wenteng Chen, Yongping Yu, Jiaan Shao, Xingguang Liang, Yujie Huang, Feng Han, Mingzhu Huang
Publikováno v:
Chemical Communications. 55:7327-7330
Autofluorescing carboline-fluors were efficiently and rationally developed via a Pictet-Spengler involved one-pot multi-component reaction. The carboline-fluors demonstrate specific targeting towards the endoplasmic reticulum in living cells, and sup
Autor:
Mingzhu Huang, Yong Ren, Yujie Huang, Xiaozhuan Li, Xingguang Liang, Feng Han, Xin Li, Juan Cheng
Publikováno v:
Analytical chemistry. 92(1)
Interrogating metabolite crosstalk in live cells is important to understand the interplay between metabolic and signal transduction pathways but is challenging due to the lack of efficient analytical techniques. Here we report a sequentially activate
Autor:
Yifeng Han, Siyao Qin, Juan Cheng, Gang Wang, Xingguang Liang, Feng Han, Mingzhu Huang, Ling-Xiao Shao, Xin Li
Publikováno v:
Chemical Communications. 54:12010-12013
Using the conformational restraint strategy, we developed a hydrazonate-derived coumarin into a lysosome targeting probe for imaging native formaldehyde at the subcellular level. Using this probe, we observed the overproduction of formaldehyde in lys
Autor:
Xingguang Liang, Qing-Qing Fang, Dong-Sheng Hong, Wei-Qiang Tan, He Zhu, Zheng-Cai Wang, Ying Hu, Dong Lou, Qingwei Zhao
Publikováno v:
Journal of International Medical Research. 49:030006052199767
Objective To investigate if co-transfection of human bone morphogenetic protein 2 (BMP-2, BMP2) and human fibroblast growth factor 2 (FGF2, FGF2) via chitosan nanoparticles promotes osteogenesis in human adipose tissue-derived stem cells (ADSCs) in v