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pro vyhledávání: '"Xingfang J. Hong"'
Autor:
Maria L. Garcia, Frank Kayser, Peter J. Sinclair, Mary Jo Staruch, Andrew Kotliar, Nancy N. Tsou, William H. Parsons, Marty S. Springer, Gloria C. Koo, Kathleen M. Rupprecht, William A. Schmalhofer, Gregory J. Kaczorowski, Robert S. Slaughter, Joung L. Goulet, Kashmira Shah, Jianming Bao, Xingfang J. Hong, Frederick Wong, Shouwu Miao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 13:1161-1164
The voltage-gated potassium channel, Kv1.3, is present in human T-lymphocytes. Blockade of Kv1.3 results in T-cell depolarization, inhibition of T-cell activation, and attenuation of immune responses in vivo. A class of benzamide Kv1.3 channel inhibi