Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Xingdang Liu"'
Publikováno v:
iRADIOLOGY, Vol 2, Iss 4, Pp 396-411 (2024)
Abstract Targeted alpha (α) therapy (TAT) is an emerging therapeutic strategy for cancer treatment. To evaluate the safety and efficacy of targeted α‐therapy, the biodistribution and internal radiation dose of α‐emitting radionuclides should b
Externí odkaz:
https://doaj.org/article/8e574c0327a246fbb68ba7bcc4de0e16
Autor:
Huiling Chen, Jingjing Lou, Meiyuan Dong, Xintao Liu, Shijie Yan, Song Wen, Ligang Zhou, Xingdang Liu, Xinlu Yuan
Publikováno v:
BMC Geriatrics, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Sarcopenia, an age-related disorder characterized by loss of skeletal muscle mass and function, is recently recognized as a complication in elderly patients with type 2 diabetes mellitus (T2DM). Skeletal muscles play a crucial rol
Externí odkaz:
https://doaj.org/article/cbb90de7e8b34852a5a392e3504f2c40
Autor:
Haijun Yang, Can Zhou, Guanyu Xu, Tingfang Wang, Biyue Zhu, Jingjing Lou, Xiao Li, Xingdang Liu, Jian Yang
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101325- (2024)
Abnormal accumulation amyloid-β (Aβ) is recognized as one of the crucial factors for the progression and pathology of AD, which has accelerated the development of new chemical agents or technology for early mapping and monitoring Aβ plagues. While
Externí odkaz:
https://doaj.org/article/a61645668fe04378b6683e935cd9dda3
Autor:
Han Wu, Zhe Lei, Yinghui Ou, Xin Shi, Qian Xu, Keqing Shi, Jing Ding, Qianhua Zhao, Xiuzhe Wang, Xiaolong Cai, Xueyuan Liu, Jingjing Lou, Xingdang Liu
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
ObjectiveThe aim was to study whether the computed tomography (CT) density and β-amyloid (Aβ) level of intraorbital optic nerve could assist in diagnosing mild cognitive impairment (MCI) and Alzheimer’s disease (AD).MethodsA total of sixty subjec
Externí odkaz:
https://doaj.org/article/1bd997ad5e124617a03d53589f72c2ac
Autor:
Yujing Zhou, Xingdang Liu
Publikováno v:
Biomarker Research, Vol 8, Iss 1, Pp 1-12 (2020)
Abstract Breast cancer, a malignant tumor originating from mammary epithelial tissue, is the most common cancer among women worldwide. Challenges facing the diagnosis and treatment of breast cancer necessitate the search for new mechanisms and drugs
Externí odkaz:
https://doaj.org/article/02b30b3601994ecd91570052d58a3815
Autor:
Shasha Xu, Shaoang Tu, Jinlong Gao, Jia Liu, Zhirui Guo, Jinming Zhang, Xingdang Liu, Jianhui Liang, Yiyun Huang, Mei Han
Publikováno v:
BMC Complementary and Alternative Medicine, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background Methamphetamine (METH) is a psychostimulant with high abuse liability that affects the monoamine neurotransmitter systems, particularly the dopamine system. Currently there are no effective medications for the treatment of METH ab
Externí odkaz:
https://doaj.org/article/8d569ae51c5d4143b9a009ccc1a2e02c
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 1, Pp 373-382 (2017)
Background/Aims: Circulating tumor cells (CTCs) are valuable in both basic research and clinical application for cancer management. In the current study, we evaluated the diagnostic value of CTCs in pancreatic ductal adenocarcinoma (PDAC). Methods: I
Externí odkaz:
https://doaj.org/article/6f8c18de34e14f25b9629e1d0aad84c2
Publikováno v:
Annals of Nuclear Medicine. 37:219-226
Autor:
Yujing Zhou, Peng Lei, Jiaxin Han, Zhiming Wang, Aiyan Ji, Yuyang Wu, Lingling Zheng, Xiaoqing Zhang, Chunrong Qu, Jian Min, Weiliang Zhu, Zhijian Xu, Xingdang Liu, Hao Chen, Zhen Cheng
Publikováno v:
Journal of Medicinal Chemistry. 66:1210-1220
Purpose: Estrogen receptors beta (ERβ) is an important ER subtype and plays crucial roles in many physiological and pathological disorders. Herein, we aim to develop a probe, 18F-PVBO, for in vivo ERβ targeted PET imaging with promising results.Met
Autor:
Lingling Zheng, Zhiming Wang, Xiaoqing Zhang, Yujing Zhou, Aiyan Ji, Hongyue Lou, Xingdang Liu, Hao Chen, Zhen Cheng
Publikováno v:
Journal of Medicinal Chemistry. 65:497-506
Mitochondria-targeting positron emission tomography (PET) and fluorescent dual-modal probes are rarely reported. As one of the most promising lipophilic cations, F16 and its derivatives (F16s) have never been used for myocardial imaging. In this work