Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Xingbin Ai"'
Autor:
Gaurang M. Amonkar, Richard Wagner, Kamakshi Bankoti, Jessica E. Shui, Xingbin Ai, Paul H. Lerou
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101390- (2022)
Summary: Patient-specific airway basal stem cells (BSCs) can be derived from tracheal aspirate (TA) samples from intubated patients, thus providing an invaluable lung stem cell derivation method that bypasses the need for lung tissue. The primary cul
Externí odkaz:
https://doaj.org/article/b034a18d198e474e8fbf9b4e3455547d
Autor:
Jessica E. Shui, Wei Wang, Helu Liu, Anna Stepanova, Grace Liao, Jun Qian, Xingbin Ai, Vadim Ten, Jining Lu, Wellington V. Cardoso
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract The impact of prematurity on human development and neonatal diseases, such as bronchopulmonary dysplasia, has been widely reported. However, little is known about the effects of prematurity on the programs of stem cell self-renewal and diffe
Externí odkaz:
https://doaj.org/article/553bcca3e5344c2da2c372b094691afd
Autor:
Wei Wang, Xingbin Ai
Publikováno v:
STAR Protocols, Vol 2, Iss 3, Pp 100756- (2021)
Summary: Primary T-cell culture is an invaluable model for investigating mechanisms underlying T-cell differentiation and function in health and disease. However, different culture conditions are required for immature versus mature CD4+ T cells. Here
Externí odkaz:
https://doaj.org/article/11d48b1ae5b94743b76468bfc0cb2300
Autor:
Julia Hicks-Berthet, Boting Ning, Anthony Federico, Andrew Tilston-Lunel, Adeline Matschulat, Xingbin Ai, Marc E. Lenburg, Jennifer Beane, Stefano Monti, Xaralabos Varelas
Publikováno v:
Cell Reports, Vol 36, Iss 2, Pp 109347- (2021)
Summary: Proper lung function relies on the precise balance of specialized epithelial cells that coordinate to maintain homeostasis. Herein, we describe essential roles for the transcriptional regulators YAP/TAZ in maintaining lung epithelial homeost
Externí odkaz:
https://doaj.org/article/51d769715d5644f496c2be0ccf9745a0
Autor:
Hongmei Mou, Ying Yang, Molly A. Riehs, Juliana Barrios, Manjunatha Shivaraju, Adam L. Haber, Daniel T. Montoro, Kimberly Gilmore, Elisabeth A. Haas, Brankica Paunovic, Jayaraj Rajagopal, Sara O. Vargas, Robin L. Haynes, Alan Fine, Wellington V. Cardoso, Xingbin Ai
Publikováno v:
Cell Reports, Vol 35, Iss 3, Pp 109011- (2021)
Summary: Pulmonary neuroendocrine cells (PNECs) have crucial roles in airway physiology and immunity by producing bioactive amines and neuropeptides (NPs). A variety of human diseases exhibit PNEC hyperplasia. Given accumulated evidence that PNECs re
Externí odkaz:
https://doaj.org/article/7621fa35a8d64e0f93f6da88caccc9ac
Autor:
Robin A. Lu, Amir A. Zeki, Sumati Ram-Mohan, Nhan Nguyen, Yan Bai, Kenneth Chmiel, Stevan Pecic, Xingbin Ai, Ramaswamy Krishnan, Chandra C. Ghosh
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Despite maximal use of currently available therapies, a significant number of asthma patients continue to experience severe, and sometimes life-threatening bronchoconstriction. To fill this therapeutic gap, we examined a potential role for the 3-hydr
Externí odkaz:
https://doaj.org/article/fc50785afe1c4c898bc1d754981d5bae
Autor:
Benjamin Stump, Shikshya Shrestha, Anthony M Lamattina, Pierce H Louis, Woohyun Cho, Mark A Perrella, Xingbin Ai, Ivan O Rosas, Florence F Wagner, Carmen Priolo, Jonathan Astin, Souheil El-Chemaly
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0213831 (2019)
Lymphatic vessels play an important role in health and in disease. In this study, we evaluated the effects of GSK3-β inhibition on lung lymphatic endothelial cells in vitro. Pharmacological inhibition and silencing of GSK3-β resulted in increased l
Externí odkaz:
https://doaj.org/article/5bd9212dd63c4546b6cdf5e5cfdc3da1
Autor:
Jesus Paez-Cortez, Ramaswamy Krishnan, Anneliese Arno, Linh Aven, Sumati Ram-Mohan, Kruti R Patel, Jining Lu, Oliver D King, Xingbin Ai, Alan Fine
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74469 (2013)
Phenotypes of lung smooth muscle cells in health and disease are poorly characterized. This is due, in part, to a lack of methodologies that allow for the independent and direct isolation of bronchial smooth muscle cells (BSMCs) and vascular smooth m
Externí odkaz:
https://doaj.org/article/ea68fdf688894b4aad74ad2f17845ba0
Autor:
Bankoti, Kamakshi, Wei Wang, Amonkar, Gaurang M., Linjie Xiong, Shui, Jessica E., Caiqi Zhao, Van, Eric, Mwase, Chimwemwe, Jin-Ah Park, Hongmei Mou, Yinshan Fang, Jianwen Que, Yan Bai, Lerou, Paul H., Xingbin Ai
Publikováno v:
American Journal of Respiratory Cell & Molecular Biology; Jan2024, Vol. 70 Issue 1, p26-38, 13p
Autor:
Florentine Dylong, Jan Riedel, Gaurang M. Amonkar, Nicole Peukert, Paula Lieckfeldt, Katinka Sturm, Benedikt Höxter, Wai Hei Tse, Yuichiro Miyake, Steffi Mayer, Richard Keijzer, Martin Lacher, Xingbin Ai, Jan-Hendrik Gosemann, Richard Wagner
Background & ObjectiveAbnormal lung development is the main cause of morbidity and mortality in neonates with congenital diaphragmatic hernia (CDH), a common birth defect (1:2500) of largely unknown pathobiology. Recent studies discovered that inflam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f2c07983fc3d43d8d982e13c351cacf
https://doi.org/10.1101/2023.04.07.536002
https://doi.org/10.1101/2023.04.07.536002
