Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Xing-yan Luo"'
Autor:
Yang Liu, Chun-Fen Mo, Xing-Yan Luo, Hua Li, Hui-Jie Guo, Hai Sun, Song Hu, Li-Mei Li, Yan-Tang Wang, Shu-Xia Yang, Shan Chang, Qiang Zou
Publikováno v:
Journal of Innate Immunity, Pp 1-17 (2019)
Toll-like receptor 3 (TLR3) is a sensor of endogenous cell necrosis during the process of acute inflammation. Interleukin (IL)-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine and can negatively regulate the pathogenesis of inflammatio
Externí odkaz:
https://doaj.org/article/d0a10990697b4de189606eb38c758489
Autor:
Jin Liu, Ning Huang, Ning Li, Si-Nian Liu, Min-Hui Li, Hua Li, Xing-Yan Luo, Yan-Tang Wang, Li-Mei Li, Qiang Zou, Yang Liu, Tai Yang
Publikováno v:
Molecules, Vol 19, Iss 11, Pp 17173-17186 (2014)
In this study, a benzimidazole derivative named BMT-1 is revealed as a potential immunomodulatory agent. BMT-1 inhibits the activity of H+/K+-ATPases from anti-CD3/CD28 activated T cells. Furthermore, inhibition the H+/K+-ATPases by use of BMT-1 shou
Externí odkaz:
https://doaj.org/article/abef3ec2ad3a4feaa95ae0a5aa80cd4f
Background: Benzothiazole and its derivatives have been extensive studied due to their versatile biological properties and pharmaceutical applications. We recently found that the BMP326 (1-(1,3-benzothiazol-2-yl)-3-(2-methoxyphenyl)-1H-pyrazol-5-ol),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c62d4384cf49a6bf3131e4dd5aac43eb
https://doi.org/10.21203/rs.3.rs-1589186/v1
https://doi.org/10.21203/rs.3.rs-1589186/v1
Autor:
Chun-fen Mo, Jun Li, Shu-xia Yang, Hui-jie Guo, Yang Liu, Xing-yan Luo, Yan-tang Wang, Min-hui Li, Jing-yi Li, Qiang Zou
Publikováno v:
British Journal of Cancer
Background Hepatitis B virus (HBV) has a crucial role in the progression of hepatocellular carcinoma (HCC). Tumour cells must develop anoikis resistance in order to survive before metastasis. This study aimed to investigate the mechanism of IQGAP1 in
Autor:
Shan Chang, Hu Song, Qiang Zou, Hai Sun, Xing-Yan Luo, Yang Liu, Shu-Xia Yang, Chun-Fen Mo, Li-Mei Li, Hui-Jie Guo, Hua Li, Yantang Wang
Publikováno v:
Journal of Innate Immunity, Pp 1-17 (2019)
J Innate Immun
J Innate Immun
Toll-like receptor 3 (TLR3) is a sensor of endogenous cell necrosis during the process of acute inflammation. Interleukin (IL)-1 receptor antagonist (IL-1Ra) is an anti-inflammatory cytokine and can negatively regulate the pathogenesis of inflammatio
Autor:
Jing-Yi Li, Yang Liu, Qiang Zou, Chun-Fen Mo, Yantang Wang, Minhui Li, Hui-Jie Guo, Xing-Yan Luo, Shu-Xia Yang, Jun Li
Publikováno v:
Br J Cancer
Hepatitis B virus (HBV) has a crucial role in the progression of hepatocellular carcinoma (HCC). Tumour cells must develop anoikis resistance in order to survive before metastasis. This study aimed to investigate the mechanism of IQGAP1 in HBV-mediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca4a153132382c7ec366b2d97e7b0f8
https://europepmc.org/articles/PMC8367952/
https://europepmc.org/articles/PMC8367952/
Autor:
Zhao Shi, Jing Wang, Wen‑Jing Zhou, Xing‑Yan Luo, Jia‑Yi Zhang, Ting Zeng, Zi‑Hao Chen, Hong‑Yu Li, Hui‑Jie Guo, Chun‑Fen Mo, Jia‑Jie Li
Publikováno v:
Oncology Letters
Nicotinamide phosphoribosyltransferase (NAMPT) is a critical rate-limiting enzyme involved in NAD synthesis that has been shown to contribute to the progression of liver cancer. However, the potential role and mechanism of NAMPT in hepatitis B virus
Autor:
Qiang Zou, Xing-Yan Luo, Yang Liu, Yi Lai, Yantang Wang, Jing Xiong, Si-Yu Wang, Hui-Jie Guo, Chun-Fen Mo, Li-Mei Li, Shu-Xia Yang
Publikováno v:
Br J Pharmacol
Background and purpose Immunosuppressive drugs have shown great promise in treating autoimmune diseases in recent years. A series of novel oxazole derivatives were screened for their immunosuppressive activity. PO-322 [1H-indole-2,3-dione 3-(1,3-benz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c61e4e051ee2e5375e901335623581
https://europepmc.org/articles/PMC7060359/
https://europepmc.org/articles/PMC7060359/
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2020)
Frontiers in Pharmacology
Frontiers in Pharmacology
As a GSK-3β inhibitor reported by our group, K313 is a novel benzoxazole derivative and displays anti-inflammatory properties in RAW264.7 macrophages without cytotoxicity. The activity of GSK-3β affects the differentiation and maturation of bone ma
Autor:
Li-Mei Li, Min-Hui Li, Shu-Xia Yang, Ping Yang, Kun Zhang, Jin Liu, Xing-Yan Luo, Chong-Jie Zhang, Qiang Zou, Tai Yang, Yang Liu
Publikováno v:
International Journal of Oncology. 49:2127-2134
Benzothiazole derivatives are known for various biological activities, and their potency in cancer therapy have received considerable attention in recent years. However, the poor water solubility of most benzothiazole derivatives has limited their cl