Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Xing-gui Chen"'
Autor:
Dan He, Xiao-qin Zhao, Xing-gui Chen, Yi Fang, Satyakam Singh, Tanaji T Talele, Hui-juan Qiu, Yong-ju Liang, Xiao-kun Wang, Guo-qing Zhang, Zhe-sheng Chen, Li-wu Fu
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54181 (2013)
ATP-binding-cassette family membrane proteins play an important role in multidrug resistance. In this study, we investigated BIRB796, an orally active inhibitor of p38 mitogen-activated protein kinase, reversed MDR induced by ABCB1, ABCG2 and ABCC1.
Externí odkaz:
https://doaj.org/article/3c26397f57974182b21481b99906be2e
Autor:
Guang-quan Li, Xing-gui Chen, Xing-ping Wu, Jing-dun Xie, Yong-ju Liang, Xiao-qin Zhao, Wei-qiang Chen, Li-wu Fu
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48994 (2012)
Dicycloplatin, a new supramolecular platinum-based antitumor drug, has been approved by the State Food and Administration (SFDA) of China. In this study, we investigated the anticancer activity of dicycloplatin in cancer cells and signaling pathways
Externí odkaz:
https://doaj.org/article/796b04108c9e4f5d953bf9806586dc13
Autor:
Hua Wang, Bi-bo Fu, Zhi-jun Wuxiao, Ya-jun Li, Li Huang, Jie Ma, Zhi-min Zhai, Jing Guo, Yuan-bin Wu, Zhen-shu Xu, Jia Feng, Sheng-sheng Zhou, Ting-ting Chen, Xing-gui Chen, Guo-wei Li, Ting-zhi Liu, Hai-bin Huang, Run-hui Zheng, Yong-hua Li, Hong-fang Tao, Fu-ming Zi, Fan Wu, Juan Wang, Hui Zeng, Cai-bo Fu, Robert Peter Gale, Zhong-jun Xia, Yang Liang
Publikováno v:
Leukemia. 36:2724-2728
Saracatinib (AZD0530) is a potent modulator of ABCB1-mediated multidrug resistancein vitroandin vivo
Autor:
Tanaji T. Talele, Satyakam Singh, Hong-May Sim, Ke Jun Liu, Xiao Dong Su, Li Wu Fu, Fang Wang, Jing Dun Xie, Yong Ju Liang, Xing Gui Chen, Suresh V. Ambudkar, Hai Ying Wu, Jie Hua He, Kamlesh Sodani, Zhe-Sheng Chen
Publikováno v:
International Journal of Cancer. 132:224-235
Saracatinib, a highly selective, dual Src/Abl kinase inhibitor, is currently in a Phase II clinical trial for the treatment of ovarian cancer. In our study, we investigated the effect of saracatinib on the reversal of multidrug resistance (MDR) induc
Autor:
Xing Ping Wu, Chao Cheng, Shu Peng Chen, Yong Ju Liang, Fang Wang, Zhenguo Liu, Li Wu Fu, Yan Jun Mi, Kenneth K.W. To, Xing Gui Chen
Publikováno v:
Molecular Medicine. 18:887-898
Stemlike cells have been isolated by their ability to efflux Hoechst 33342 dye and are called the side population (SP). We evaluated the effect of axitinib on targeting cancer stemlike cells and enhancing the efficacy of chemotherapeutical agents. We
Autor:
Tong Yu Lin, Cheng Cheng Guo, Xing Gui Chen, Rui Qing Cai, Ying Tian, He Huang, Chao Yong Liang, Ben Yan Zou, Yao Ling Gong
Publikováno v:
Chinese Journal of Cancer
Angioimmunoblastic T-cell lymphoma (AITL) is a rare, distinct subtype of peripheral T-cell lymphoma, possessing an aggressive course and poor prognosis with no standard therapy. Twelve patients who have failed at least two initial CHOP or CHOP-like r
Publikováno v:
Asian Pacific journal of cancer prevention : APJCP. 15(14)
Background: Agrocybe aegerita Lectin (AAL) has been identified to have high affinity for sulfated and α2-3- linked sialic acid glycoconjugates, especially the sulfated and sialyl TF (Thomsen-Friedenreich) disaccharide. This study was conducted to in
Autor:
Hui Juan Qiu, Satyakam Singh, Xiao Kun Wang, Guo qing Zhang, Li Wu Fu, Tanaji T. Talele, Yong Ju Liang, Zhe-Sheng Chen, Xiao Qin Zhao, Xing Gui Chen, Dan He, Yi Fang
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 1, p e54181 (2013)
PLoS ONE, Vol 8, Iss 1, p e54181 (2013)
ATP-binding-cassette family membrane proteins play an important role in multidrug resistance. In this study, we investigated BIRB796, an orally active inhibitor of p38 mitogen-activated protein kinase, reversed MDR induced by ABCB1, ABCG2 and ABCC1.
Autor:
Xu Zhang, Suresh V. Ambudkar, Xiao Qin Zhao, Satyakam Singh, Yue-Li Sun, Zhe-Sheng Chen, Yong Ju Liang, Xing Gui Chen, Tanaji T. Talele, Hong-May Sim, Jing Dun Xie, Li Wu Fu
Neratinib, an irreversible inhibitor of epidermal growth factor receptor and human epidermal receptor 2, is in phase III clinical trials for patients with human epidermal receptor 2-positive, locally advanced or metastatic breast cancer. The objectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6134afa32c8dce45a1b74623d427e622
https://europepmc.org/articles/PMC3382829/
https://europepmc.org/articles/PMC3382829/
Autor:
Yong Ju Liang, Fo Tian Zhong, Chao Cheng, Jun Jiang Chen, Zhe-Sheng Chen, Jing Dun Xie, Fang Wang, Li Wu Fu, Zhenguo Liu, Li Kun Chen, Xing Gui Chen, Xiao Qin Zhao, Satyakam Singh, Hui Zhang, Tanaji T. Talele
Publikováno v:
Molecular pharmaceutics. 9(7)
Imidazopyridine CCT129202 is an inhibitor of Aurora kinase activity and displays a favorable antineoplastic effect in preclinical studies. Here, we investigated the enhanced effect of CCT129202 on the cytotoxicity of chemotherapeutic drugs in multidr