Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xing-Zhong Xia"'
Autor:
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
There is an unmet need in severe asthma where approximately 40% of patients exhibit poor β-agonist responsiveness, suffer daily symptoms and show frequent exacerbations. Antagonists of the Ca2+-activated Cl− channel, TMEM16A, offers a new mechanis
Externí odkaz:
https://doaj.org/article/41d8cbf66f0741758aee1902a2f9ab21
Autor:
John M. Delaney, Xing-Zhong Xia, Nessa Hawkins, Meena Ramakrishnan, Gang Yu, Masayo Kornuc, Susan McCabe, Tom Boone, Lars Eyde Theill, Wan-rong Qiu, Giorgio Senaldi, Ildiko Sarosi, Jane Guo, Marina Stolina, Hailing Hsu, Michael J. Kelley, William J. Boyle
Publikováno v:
Nature Immunology. 1:252-256
We report that the tumor neurosis factor homolog APRIL (a proliferation-inducing ligand) stimulates in vitro proliferation of primary B and T cells and increases spleen weight due to accumulation of B cells in vivo. APRIL functions via binding to BCM
Autor:
Kent Miner, Irina Solovyev, Gwyneth Van, Ling Wang, Xing-Zhong Xia, Nessa Hawkins, Hailing Hsu, David L. Lacey, Ildiko Sarosi, David K. Chang, John K. Delaney, Larry Ross, Michael J. Kelley, Sanjay D. Khare, William J. Boyle, Susan McCabe
Publikováno v:
Proceedings of the National Academy of Sciences. 97:3370-3375
TALL-1/Blys/BAFF is a member of the tumor necrosis factor (TNF) ligand superfamily that is functionally involved in B cell proliferation. Here, we describe B cell hyperplasia and autoimmune lupus-like changes in transgenic mice expressing TALL-1 unde
Autor:
Irina Solovyev, John M. Delaney, Sanjay D. Khare, Shi-Yuan Meng, Anne Colombero, James J. S. Treanor, Susan McCabe, Robin Elliott, William J. Boyle, Gang Yu, Xing-Zhong Xia, Michael J. Kelley, Giorgio Senaldi, Judy Wang, Kent Miner, Frances Lee, Nessa Hawkins, Marina Stolina, Jane Guo, Lars Eyde Theill, Hailing Hsu, Tom Boone
Publikováno v:
The Journal of Experimental Medicine
We and others recently reported tumor necrosis factor (TNF) and apoptosis ligand–related leukocyte-expressed ligand 1 (TALL-1) as a novel member of the TNF ligand family that is functionally involved in B cell proliferation. Transgenic mice overexp
Autor:
Hailing Hsu, Gary Elliott, Michael Bass, Ildiko Sarosi, Emma Timms, Ling Wang, Michael J. Kelley, Casey Capparelli, David L. Lacey, Robin Elliott, Sheila Scully, Laura Chiu, Xing-Zhong Xia, Hong-Lin Tan, Grant Shimamoto, Irina Solovyev, Sean Morony, William J. Boyle, Anne Colombero, Colin R. Dunstan, Tabitha Black
Publikováno v:
Proceedings of the National Academy of Sciences. 96:3540-3545
A receptor that mediates osteoprotegerin ligand (OPGL)-induced osteoclast differentiation and activation has been identified via genomic analysis of a primary osteoclast precursor cell cDNA library and is identical to the tumor necrosis factor recept
Publikováno v:
Differentiation. 57:143-149
Prostatic acid phosphatase (PAcP) is a prostate epithelium-specific differentiation antigen. It has been demonstrated that human PAcP exhibits endogenous protein tyrosine phosphatase (PYP) activity, and that it represents the major PYP activity in no
Autor:
You Chen Chao, Renee Garcia-Arenas, Xing Zhong Xia, Michael M.C. Lai, Pravin C. Patel, Ming Fong Lin
Publikováno v:
Archives of biochemistry and biophysics. 300(1)
The expression and the secretion of human prostatic acid phosphatase (PAcP), a differentiation antigen which is the major acid phosphatase in prostate epithelial cells, are thought to be regulated by an androgen. We investigated this regulatory mecha