Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Xing-Xing Shi"'
Autor:
Ming-Shu Wang, Yi Gong, Lin-Sheng Zhuo, Xing-Xing Shi, Yan-Guang Tian, Chang-Kang Huang, Wei Huang, Guang-Fu Yang
Publikováno v:
Research, Vol 2022 (2022)
Conventional methods of drug design require compromise in the form of side effects to achieve sufficient efficacy because targeting drugs to specific organs remains challenging. Thus, new strategies to design organ-specific drugs that induce little t
Externí odkaz:
https://doaj.org/article/a99869e467ef46019b063c9cd2797b38
Autor:
Xing-Xing Shi, Bai-Shuang Yin, Peng Yang, Hao Chen, Xin Li, Li-Xue Su, Hong-Gang Fan, Hong-Bin Wang
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153169 (2016)
Xylazine is a potent analgesic extensively used in veterinary and animal experimentation. Evidence exists that the analgesic effect can be inhibited using adenosine 5'-monophosphate activated protein kinase (AMPK) inhibitors. Considering this idea, t
Externí odkaz:
https://doaj.org/article/75dc87118afe4bfaa6b01b429b469296
Publikováno v:
Trends in Biochemical Sciences. 48:539-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea589177859b26abce26ddceec558049
https://doi.org/10.1016/j.tibs.2023.01.008
https://doi.org/10.1016/j.tibs.2023.01.008
Autor:
Jia-Xu Nan, Jin Dong, Jun-Qiao Cao, Guang-Yi Huang, Xing-Xing Shi, Xue-Fang Wei, Qiong Chen, Hong-Yan Lin, Guang-Fu Yang
Publikováno v:
Journal of Agricultural and Food Chemistry. 71:5783-5795
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ee275d5fd21076193d3c69ffc120a3c
https://doi.org/10.1021/acs.jafc.2c08448
https://doi.org/10.1021/acs.jafc.2c08448
Autor:
Xing-Xing Shi, Zhi-Zheng Wang, Xin-Lin Sun, Yu-Liang Wang, Huan-Xiang Liu, Fan Wang, Ge-Fei Hao, Guang-Fu Yang
Publikováno v:
Green Chemistry. 25:2170-2219
This review aims to introduce the rich applications of chemical toxicological data for environmental risk assessment and green chemical design by illustrating referable examples or cases. Further, we present a comprehensive toxicology databank.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b961232c09c090bc4eaac0f18ee139dd
https://doi.org/10.1039/d2gc03973g
https://doi.org/10.1039/d2gc03973g
Autor:
Xing-Xing Shi, Fan Wang, Zhi-Zheng Wang, Guang-Yi Huang, Min Li, Jesus Simal-Gandara, Ge-Fei Hao, Guang-Fu Yang
Publikováno v:
Critical Reviews in Food Science and Nutrition. :1-16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eaf238b1498f99d4d60838d5ddd9f989
https://doi.org/10.1080/10408398.2022.2152423
https://doi.org/10.1080/10408398.2022.2152423
ACFIS 2.0: an improved web-server for fragment-based drug discovery via a dynamic screening strategy
Publikováno v:
Nucleic Acids Research.
Drug discovery, which plays a vital role in maintaining human health, is a persistent challenge. Fragment-based drug discovery (FBDD) is one of the strategies for the discovery of novel candidate compounds. Computational tools in FBDD could help to i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c1d32471a2603ad467e267c4b5f995
https://doi.org/10.1093/nar/gkad348
https://doi.org/10.1093/nar/gkad348
Publikováno v:
Briefings in bioinformatics. 23(4)
Protein kinases play crucial roles in many cellular signaling processes, making them become important targets for drug discovery. But drug resistance mediated by mutation puts a barrier to the therapeutic effect of kinase inhibitors. Fragment-based d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8015e59cf919dcc0ebfa138bf2aba2bd
https://pubmed.ncbi.nlm.nih.gov/35649390
https://pubmed.ncbi.nlm.nih.gov/35649390
Autor:
Fan Wang, Chen-Yang Jia, Ge-Fei Hao, Jing-Fang Yang, Guang-Fu Yang, Xing-Xing Shi, Meng-Yao Wang
Publikováno v:
Science Bulletin. 65:1184-1191
The impact of pesticides on insect pollinators has caused worldwide concern. Both global bee decline and stopping the use of pesticides may have serious consequences for food security. Automated and accurate prediction of chemical poisoning of honey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80235b451245a5f0d74c0f478934ae4f
https://doi.org/10.1016/j.scib.2020.04.006
https://doi.org/10.1016/j.scib.2020.04.006
Publikováno v:
Journal of Chemical Education. 97:427-436
Fragment-based drug design (FBDD) is a promising methodology to find quality drug leads. It is important in the curriculum of a drug design course due to its impact on drug discovery. However, teaching FBDD and its use by students remain challenging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a7f81379bd08860fcb5ed2977bb434d
https://doi.org/10.1021/acs.jchemed.9b00198
https://doi.org/10.1021/acs.jchemed.9b00198