Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Xing-Xing Fan"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
With the COVID-19 pandemic, the importance of vaccines has been widely recognized and has led to increased research and development efforts. Vaccines also play a crucial role in cancer treatment by activating the immune system to target and destroy c
Externí odkaz:
https://doaj.org/article/fe4e7109b05b48239e1f4c597af4e6c4
Publikováno v:
Pharmacological Research, Vol 203, Iss , Pp 107174- (2024)
The emergence of immune checkpoint inhibitors (ICIs) has revolutionized the clinical treatment for tumor. However, the low response rate of ICIs remains the major obstacle for curing patients and effective approaches for patients with primary or seco
Externí odkaz:
https://doaj.org/article/ae46614f85c74f81ab4ed010af7a8dc4
Autor:
Elaine Lai-Han Leung, Run-Ze Li, Xing-Xing Fan, Lily Yan Wang, Yan Wang, Zebo Jiang, Jumin Huang, Hu-Dan Pan, Yue Fan, Hongmei Xu, Feng Wang, Haopeng Rui, Piu Wong, Hermi Sumatoh, Michael Fehlings, Alessandra Nardin, Paul Gavine, Longen Zhou, Yabing Cao, Liang Liu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-9 (2023)
Abstract Response to immunotherapy widely varies among cancer patients and identification of parameters associating with favourable outcome is of great interest. Here we show longitudinal monitoring of peripheral blood samples of non-small cell lung
Externí odkaz:
https://doaj.org/article/c845ab00de49468c83ac80f41f9fb0d6
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e23694- (2024)
The outcomes and prognosis of autoimmune diseases depend on early diagnosis and effective treatments. However, symptoms of early autoimmune diseases are often remarkably similar to many inflammatory diseases, leading to difficulty in precise diagnosi
Externí odkaz:
https://doaj.org/article/25ac06153f98440280a1ba33da527be6
Autor:
Yi-Han Zuo, Wei-Na Gao, Ya-Jia Xie, Sheng-Yong Yang, Jin-Tai Zhou, Hai-Hai Liang, Xing-Xing Fan
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-14 (2022)
Abstract Background The recruitment of a sufficient number of immune cells to induce an inflamed tumor microenvironment (TME) is a prerequisite for effective response to cancer immunotherapy. The immunological phenotypes in the TME of EGFR–mutated
Externí odkaz:
https://doaj.org/article/c43ceff5c9044977bfd37e4e9852961d
Autor:
Min Huang, Fang He, Dan Li, Ya-Jia Xie, Ze-Bo Jiang, Ju-Min Huang, Xiao-Ping Zhao, Ali Adnan Nasim, Jun-Hui Chen, Jin-Cai Hou, Xian-Ming Fan, Elaine Lai-Han Leung, Xing-Xing Fan
Publikováno v:
Cell Death and Disease, Vol 13, Iss 11, Pp 1-11 (2022)
Abstract A low response rate to immune checkpoint inhibitor (ICI) therapy has impeded its clinical use. As reported previously, an inflamed tumor microenvironment (TME) was directly correlated with patients’ response to immune checkpoint blockade (
Externí odkaz:
https://doaj.org/article/dbfbc594230341c78aed8c4fac9cd1f7
Autor:
Jun Cai PhD, Xing-Xing Fan PhD, Run-Ze Li PhD, Hong Lin PhD, Min Li PhD, Qi Song PhD, Chun Xie MS, Gregory Wong PhD, Sam Ting-Chung Liu PhD, Ya-Bing Cao PhD, Elaine Lai-Han Leung PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 22 (2023)
Objectives: Despite the development of various cancer treatment methods, chemotherapy remains the most common approach for treating cancer. The risk of tumors acquiring resistance to chemotherapy remains a significant hurdle to the successful treatme
Externí odkaz:
https://doaj.org/article/d5d95f761e3a42cf91bd5f45a1e7f2bb
Autor:
Juanhong Zhang, Jiaxin He, Jumin Huang, Xuefeng Li, Xiaoqing Fan, Wenbin Li, Guofan Wu, Chun Xie, Xing-Xing Fan, Junmin Zhang, Xiaojun Yao, Rong Wang, Elaine Lai-Han Leung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114610- (2023)
Background: Ginseng polysaccharide (GP) is one of the most abundant components in Panax ginseng. However, the absorption pathways and mechanisms of GPs have not been investigated systematically due to the challenges of their detection. Methods: The f
Externí odkaz:
https://doaj.org/article/40e8cb8d991f4856bc9dfd4f4455291e
Autor:
Cong Xu, Ze-Bo Jiang, Le Shao, Zi-Ming Zhao, Xing-Xing Fan, Xinbing Sui, Li-Li Yu, Xuan-Run Wang, Ruo-Nan Zhang, Wen-Jun Wang, Ya-Jia Xie, Yi-Zhong Zhang, Xiao-Wen Nie, Chun Xie, Ju-Min Huang, Jing Wang, Jue Wang, Elaine Lai-Han Leung, Qi-Biao Wu
Publikováno v:
Pharmacological Research, Vol 191, Iss , Pp 106739- (2023)
Nearly half of all Asian non-small cell lung cancer (NSCLC) patients harbour epidermal growth factor receptor (EGFR) mutations, and first-generation EGFR tyrosine kinase inhibitors (TKIs) are one of the first-line treatments that have improved the ou
Externí odkaz:
https://doaj.org/article/2d1e9702c6ab455085c9c03e552d064a
Autor:
Xiao-Ping Zhao, Xiao-Li Zheng, Min Huang, Ya-Jia Xie, Xiao-Wen Nie, Ali Adnan Nasim, Xiao-Jun Yao, Xing-Xing Fan
Publikováno v:
Heliyon, Vol 9, Iss 5, Pp e15812- (2023)
Although some important advances have been achieved in clinical and diagnosis in the past few years, the management of non-small cell lung cancer (NSCLC) is ultimately dissatisfactory due to the low overall cure and survival rates. Epidermal growth f
Externí odkaz:
https://doaj.org/article/16f80f5cb7ad4f08992f81f1163f76b7