Anti-echinococcal effect of verapamil involving the regulation of the calcium/calmodulin-dependent protein kinase II response in vitro and in a murine infection model

Autor: Hai-Jun Gao, Xu-Dong Sun, Yan-Ping Luo, Hua-Sheng Pang, Xing-Ming Ma, Ting Zhang, Tao Jing, Wei Hu, Yu-Juan Shen, Jian-Ping Cao

Publikováno v: Parasites & Vectors, Vol 14, Iss 1, Pp 1-10 (2021)

Abstract Background Echinococcosis, which is caused by the larvae of cestodes of the genus Echinococcus, is a parasitic zoonosis that poses a serious threat to the health of humans and animals globally. Albendazole is the drug of choice for the treat

Externí odkaz: https://doaj.org/article/592c91dd38234f3abcc6a7553da55bb1

Potential Chemoprevention of Paeoniflorin in Colitis-Associated Colorectal Cancer by Network Pharmacology, Molecular Docking, and In Vivo Experiment

Autor: Xiao‐Li Si, Yan Wang, Bo‐Ni Song, Yan Zhang, Qing‐Xia Yang, Zhi Li, Yan‐Ping Luo, Yong‐Qiang Duan, Xing‐Ming Ma, Yan‐Ying Zhang

Publikováno v: Chemistrybiodiversity. 19(8)

Chronic inflammation plays a positive role in the development and progression of colitis-associated colorectal cancer (CAC). Medicinal plants and their extracts with anti-inflammatory and immunoregulatory properties may be an effective treatment and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36acdceadbb468b5890ef071d41e601
https://pubmed.ncbi.nlm.nih.gov/35841592

Anti-echinococcal effect of verapamil involving regulating calcium/calmodulin-dependent protein kinase Ⅱ response in vitro and in a murine infection model

Autor: Hai-Jun Gao, Xu-Dong Sun, Yan-Ping Luo, Hua-Sheng Pang, Xing-Ming Ma, Ting Zhang, Tao Jing, Wei Hu, Yu-Juan Shen, Jian-Ping Cao

Background: Echinococcosis caused by the larval stage of cestode of the genus Echinococcus is a parasitic zoonosis, imposing serious threat on the health of humans and animals globally. Albendazole is the drug of choice for treatment of echinococcosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0f565e02d6a4f8e46acbc21b4c278dc8
https://doi.org/10.21203/rs.3.rs-107151/v1

Semisynthesis, an Anti-Inflammatory Effect of Derivatives of 1β-Hydroxy Alantolactone from Inula britannica

Autor: Ping Xiang, Jiang-Jiang Tang, Jian-Ping Zhang, Xin Liu, Xing-Ming Ma, Lin Chen

Publikováno v: Molecules; Volume 22; Issue 11; Pages: 1835
Molecules, Vol 22, Iss 11, p 1835 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry

1β-hydroxy alantolactone, a sesquiterpene lactone mainly isolated from Inula genus plants, exhibits potent anti-inflammatory and anticancer activities. In this work, 1β-hydroxy alantolactone was isolated and five derivatives were prepared through d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e828f4c946517d2320cd5f032ca10a

Numerical Simulation of Distribution of Discharged Gas Fire Extinguishing Agent in High Velocity Flow Field

Autor: Jun Qin, Di Di Li, Yu Chong Han, Jia Jia Fu, Xing Ming Ma, Yu Nong Li, Lan Ming Zhao

Publikováno v: Advanced Materials Research. :1786-1791

This paper studied the concentration distribution of gas extinguishing agent numerically in high velocity flow field. Civil aircraft power plant compartment has been a difficult area for its high velocity flow field formed after fire happens. Focusin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e0bc66f81383bf82d660b9183e881702
https://doi.org/10.4028/www.scientific.net/amr.718-720.1786