Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xing Wen Gong"'
Autor:
L. Ravithej Singh, Yu-Lin Chen, Yuan-Yuan Xie, Wei Xia, Xing-Wen Gong, Robert C. Hider, Tao Zhou
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1562-1567 (2020)
In an attempt to synthesise new tyrosinase inhibitors, we designed and synthesised a series of chalcone-hydroxypyridinone hybrids as potential tyrosinase inhibitors adopting strategic modifications of kojic acid. All the newly synthesised compounds w
Externí odkaz:
https://doaj.org/article/1f54c5fec4ba449f9607c6974b604ecb
Autor:
Bo-Chen Chen, Zhi-Shan Ding, Jian-Sheng Dai, Ni-Pi Chen, Xing-Wen Gong, Lie-Feng Ma, Chao-Dong Qian
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The rapid rise of antibiotic resistance causes an urgent need for new antimicrobial agents with unique and different mechanisms of action. The respiratory chain is one such target involved in the redox balance and energy metabolism. As a natural quin
Externí odkaz:
https://doaj.org/article/1e3b7a0b26c4443ea48e4f494f331f71
Autor:
Nipi Chen, Xing-Wen Gong, Chao-Dong Qian, Zhishan Ding, Bo-Chen Chen, Jian-Sheng Dai, Lie-Feng Ma
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
The rapid rise of antibiotic resistance causes an urgent need for new antimicrobial agents with unique and different mechanisms of action. The respiratory chain is one such target involved in the redox balance and energy metabolism. As a natural quin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6c70050d6e507a9491a4039254e40d5
Publikováno v:
Protein Expression and Purification. 110:37-42
Penicillin-binding protein 3 (PBP3) of Pseudomonas aeruginosa is the primary target of β-lactams used to treat pseudomonas infections. Meanwhile, structure change and overproduction of PBP3 play important roles in the drug resistance of P. aeruginos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469f19be8168c0b006a5e3233dca9b42
https://doi.org/10.1016/j.pep.2014.12.004
https://doi.org/10.1016/j.pep.2014.12.004
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 22:2388-2392
The angiopoietin–Tie2 binding and related signal transduction pathways are crucial for vascular angiogenesis, blood vessel integrity and maturation. In this study, we preformed a virtual screening of small molecules targeting to Tie2. The binding s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8106e4fb18c8ea76eb08654df65e5656
https://doi.org/10.1016/j.bmcl.2012.02.036
https://doi.org/10.1016/j.bmcl.2012.02.036
Publikováno v:
Pharmacological Research. 65:372-378
Loperamide, an antidiarrhea drug, is a peripheral opiate agonist. Some other opiate agonists have been shown to promote cell apoptosis. In this research, we studied the apoptosis-inducing and cytotoxic activities of loperamide. MTT assay was used to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7090d3b21737e4f7922b2d33e30a666
https://doi.org/10.1016/j.phrs.2011.11.007
https://doi.org/10.1016/j.phrs.2011.11.007
Publikováno v:
Analytical Biochemistry. 354:157-158
modification (i.e., pegyla-tion) is an effective approach to enhancing pharmaceuticalprotein’s delivery (e.g., increasing stability and solubility,prolonging plasma half-life, decreasing toxicity, and antige-nicity) [1]. The protein determination
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0bb62ad0e68ab400c590b4dcbdf1de0
https://doi.org/10.1016/j.ab.2006.04.020
https://doi.org/10.1016/j.ab.2006.04.020