Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xing Q. Pan"'
Publikováno v:
Pharmaceutical Research. 20:417-422
Purpose. The expression of folate receptor (FR) is amplified in many types of human cancers. Previously, FR-targeted liposomal doxorubicin (f-L-DOX) has been shown to exhibit superior and selective cytotoxicity against FR(+) tumor cells in vitro comp
Publikováno v:
Blood. 100:594-602
Up-regulation of folate receptor (FR) type-β in acute myelogenous leukemia (AML) by all-trans retinoic acid (ATRA) and its restricted normal tissue distribution makes it a potential target for therapeutic intervention. The FR-β in peripheral blood
Autor:
Xing Q. Pan, Werner Tjarks, Supriya Shukla, Rolf F. Barth, Robert J. Lee, Masaru Sekido, Dianne M. Adams, Huaqing Wang
Publikováno v:
Bioconjugate Chemistry. 13:435-442
Boron neutron capture therapy (BNCT) depends on the selective delivery of a sufficient number of (10)B atoms to tumor cells to sustain a lethal (10)B(n,alpha)(7)Li reaction. Expression of FR frequently is amplified among human tumors. The goal of the
Publikováno v:
Anticancer research. 25(5)
It has long been known that the polycarbohydrates on the neoplastic cell surface are different from those on normal cells; differences which allow one to attack tumor cells selectively. Although the exact differences between tumor cells and normal ce
Autor:
Xing Q, Pan, Robert J, Lee
Publikováno v:
Anticancer research. 25(1A)
Folate receptor (FR) is selectively amplified among human tumors, including in 70% of myeloid leukemias. FR-targeted liposomal delivery is an attractive strategy for enhancing the therapeutic efficacy of anticancer agents against FR(+) tumors. In thi
Penetration into solid tumor tissue of fluorescent latex microspheres: a mimic of liposome particles
Publikováno v:
Anticancer research. 24(5A)
Using liposomes as a vehicle to transport anticancer drugs to cancer cells, to increase their effectiveness and decrease their toxicity, has been studied for many years. However, due to technical difficulties, the path of penetration for liposome par
Publikováno v:
Pharmaceutical research. 20(3)
The expression of folate receptor (FR) is amplified in many types of human cancers. Previously, FR-targeted liposomal doxorubicin (f-L-DOX) has been shown to exhibit superior and selective cytotoxicity against FR(+) tumor cells in vitro compared to n
Publikováno v:
Anticancer research. 22(3)
Folate receptor (FR) is amplified in a variety of human tumors. Folate-derived liposomes have been shown to selectively deliver entrapped agents into tumor cells via receptor-mediated endocytosis. In this preliminary study, the biodistribution of FR-