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pro vyhledávání: '"Xing, Jianhua"'
Autor:
Kwon, Jungeun Sarah, Everetts, Nicholas J., Wang, Xia, Wang, Weikang, Della Croce, Kimiko, Xing, Jianhua, Yao, Guang
Quiescence is a non-proliferative cellular state that is critical to tissue repair and regeneration. Although often described as the G0 phase, quiescence is not a single homogeneous state. As cells remain quiescent for longer durations, they move pro
Externí odkaz:
http://hdl.handle.net/10150/625987
http://arizona.openrepository.com/arizona/handle/10150/625987
http://arizona.openrepository.com/arizona/handle/10150/625987
Autor:
Xing, Jianhua
Cells with the same genome can exist in different phenotypes. and can change between distinct phenotypes when subject to specific stimuli and microenvironments. Some examples include cell differentiation during development, reprogramming for induced
Externí odkaz:
http://arxiv.org/abs/2203.14964
Phenotype transition takes place in many biological processes such as differentiation, and understanding how a cell reprograms its global gene expression profile is a problem of rate theories. A cell phenotype transition accompanies with switching of
Externí odkaz:
http://arxiv.org/abs/2107.03581
Epithelial-Mesenchymal Transition (EMT), and the corresponding reverse process, Mesenchymal-Epithelial Transition (MET), are dynamic and reversible cellular programs orchestrated by many changes at biochemical and morphological levels. A recent surge
Externí odkaz:
http://arxiv.org/abs/1907.11174
Autor:
Igoshin, Oleg, Chen, Jing, Xing, Jianhua, Liu, Jian, Elston, Timothy C., Grabe, Michael, Kim, Kenneth S., Nirody, Jasmine, Rangamani, Padmini, Sun, Sean, Wang, Hongyun, Wolgemuth, Charles
Over the past 50 years, the use of mathematical models, derived from physical reasoning, to describe molecular and cellular systems has evolved from an art of the few to a cornerstone of biological inquiry. George Oster stood out as a pioneer of this
Externí odkaz:
http://arxiv.org/abs/1902.07787
Many cellular responses to surrounding cues require temporally concerted transcriptional regulation of multiple genes. In prokaryotic cells, a single-input-module motif with one transcription factor regulating multiple target genes can generate coord
Externí odkaz:
http://arxiv.org/abs/1901.06321
Autor:
Xing, Jianhua, Tian, Xiao-Jun
The transition between epithelial and mesenchymal (EMT) is a fundamental cellular process that plays critical roles in development, cancer metastasis, and tissue wound healing. EMT is not a binary process but involves multiple partial EMT states that
Externí odkaz:
http://arxiv.org/abs/1901.06239
Autor:
Tian, Xiao-Jun, Zhou, Dong, Fu, Haiyan, Zhang, Rong, Wang, Xiaojie, Huang, Sui, Liu, Youhua, Xing, Jianhua
Tissue fibrosis compromises organ function and occurs as a potential long-term outcome in response to acute tissue injuries. Currently, lack of mechanistic understanding prevents effective prevention and treatment of the progression from acute injury
Externí odkaz:
http://arxiv.org/abs/1810.03687
Autor:
Wang, Weikang, Taft, David A., Chen, Yi-Jiun, Zhang, Jingyu, Wallace, Callen T., Xu, Min, Watkins, Simon C., Xing, Jianhua
Publikováno v:
Computers in Biology and Medicine 108(2019) 133-141
Single cell segmentation is critical and challenging in live cell imaging data analysis. Traditional image processing methods and tools require time-consuming and labor-intensive efforts of manually fine-tuning parameters. Slight variations of image
Externí odkaz:
http://arxiv.org/abs/1803.10829
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