Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Xing, Caiyi"'
Autor:
Jiang, Xueyang, Wang, Yang, Liu, Chang, Xing, Caiyi, Wang, Yingming, Lyu, Weiping, Wang, Saisai, Li, Qihang, Chen, Tingkai, Chen, Yao, Feng, Feng, Liu, Wenyuan, Sun, Haopeng
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 January 2021 30
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Shen, Yongqing, Zong, Yijun, Yang, Yanting, Wang, Yongli, Suo, Tingting, Sun, Jiachen, Zhang, Zetao, Liu, Wei, Li, Dongli, Gao, Rui, Xing, Caiyi
Publikováno v:
American Journal of Hospice & Palliative Medicine; Jun2023, Vol. 40 Issue 6, p644-651, 8p
Autor:
Weiping Lyu, Yao Chen, Xueyang Jiang, Feng Feng, Chang Liu, Yang Wang, Qihang Li, Saisai Wang, Haopeng Sun, Wenyuan Liu, Xing Caiyi, Yingming Wang, Tingkai Chen
Publikováno v:
Bioorganic & Medicinal Chemistry. 30:115940
In the present work, a novel series of pyridinethiazole bearing benzylpiperidine hybrids were designed and synthesized as dual-target inhibitors of GSK-3β/AChE. Among them, GD29 was the most promising candidate, with an IC50 value of 0.3 μM for hAC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75456d9a135d93185558f1411ac0fe99
https://doi.org/10.1016/j.bmc.2020.115940
https://doi.org/10.1016/j.bmc.2020.115940
Autor:
Liu X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Wang K; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Wang L; School of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang , China., Kong L; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Hou S; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Wan Y; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Ma C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Chen J; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Xing X; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Xing C; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Jiang Q; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Zhao Q; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China., Cui B; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China., Huang Z; School of Pharmaceutical Sciences , Wenzhou Medical University , Wenzhou , Zhejiang , China., Li P; State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica , Chinese Academy of Medical Sciences and Peking Union Medical College , Beijing , China.; Diabetes Research Center of the Chinese Academy of Medical Sciences , Beijing , China.; CAMS Key Laboratory of Molecular Mechanism and Target Discovery of Metabolic Disorder and Tumorigenesis , Beijing , China.
Publikováno v:
Hepatology (Baltimore, Md.) [Hepatology] 2023 Aug 01; Vol. 78 (2), pp. 562-577. Date of Electronic Publication: 2022 Sep 12.