Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Xindi, Qian"'
Publikováno v:
ACS Nano. 17:5354-5372
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d12db8644a6133dc49bacd5b4ddd6344
https://doi.org/10.1021/acsnano.2c08834
https://doi.org/10.1021/acsnano.2c08834
Bioinspired nanovehicle of furoxans-oxaliplatin improves tumoral distribution for chemo-radiotherapy
Autor:
Xindi, Qian, Yuqi, Wang, Honglei, Xie, Chen, Wang, Jie, Li, Ying, Lei, Huanzhen, Liu, Yao, Wu, Yaping, Li, Zhiwen, Zhang
Publikováno v:
Journal of Controlled Release. 353:447-461
The spatiotemporal distribution of therapeutic agents in tumors remains an essential challenge of radiation-mediated therapy. Herein, we rationally designed a macrophage microvesicle-inspired nanovehicle of nitric oxide donor-oxaliplatin (FO) conjuga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c2bbaf1c6e15d5903698fe596f1d82b
https://doi.org/10.1016/j.jconrel.2022.11.044
https://doi.org/10.1016/j.jconrel.2022.11.044
Autor:
Jiaoying Wang, Jie Li, Yao Wu, Xiaoxuan Xu, Xindi Qian, Ying Lei, Huanzhen Liu, Zhiwen Zhang, Yaping Li
Publikováno v:
Nano letters. 22(20)
Despite the promising benefits of immune checkpoint inhibitors (ICIs) in clinical cancer treatments, the therapeutic efficacy is largely restricted by low antitumor immunity and limited intratumor delivery in solid tumors. Herein, we designed a react
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::322b2c0dbb36b864dd135e20e5815c7e
https://pubmed.ncbi.nlm.nih.gov/36226914
https://pubmed.ncbi.nlm.nih.gov/36226914
Autor:
Guanru Wang, Yaru Xie, Xindi Qian, Xinyue Zhang, Yanqiang Shan, Minghui Zhang, Jie Li, Zhiwen Zhang, Yaping Li
Publikováno v:
Drug development and industrial pharmacy. 48(3)
The poor water solubility and inadequate oral bioavailability of gefitinib (Gef) remain a critical issue to achieve the therapeutic outcomes. Herein, we designed a poly(maleic anhydride-alt-1-octadecene) (PMA/C18) based lipid nanovehicle (PLN) to imp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f121f23d9ce6c1e787a42d0e87363b
https://pubmed.ncbi.nlm.nih.gov/35786162
https://pubmed.ncbi.nlm.nih.gov/35786162
Autor:
Xiang Gong, Jie Li, Xiaoxuan Xu, Yao Wu, Ying Lei, Huanzhen Liu, Xindi Qian, Yaping Li, Zhiwen Zhang
Publikováno v:
Biomaterials. 290
The efficacy of radiotherapy is greatly challenged by intense hypoxia, intricate stroma and suppressive immune microenvironments in tumors. Herein, we rationally designed a microvesicle-inspired oxygen-delivering polyfluorocarbon nanosystem loading D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2422c698ea20f6b184e4a22eefce19ae
https://pubmed.ncbi.nlm.nih.gov/36257260
https://pubmed.ncbi.nlm.nih.gov/36257260
Autor:
Xindi Qian, Yuqi Wang, Honglei Xie, Chen Wang, Jie Li, Ying Lei, Huanzhen Liu, Yao Wu, Yaping Li, Zhiwen Zhang
Publikováno v:
Journal of Controlled Release. 354:207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b74571957aee3af1c3ce2b472daec221
https://doi.org/10.1016/j.jconrel.2023.01.016
https://doi.org/10.1016/j.jconrel.2023.01.016
Autor:
Xindi Qian, Xiaoxuan Xu, Yao Wu, Jiaoying Wang, Jie Li, Shuo Chen, Jingyuan Wen, Yaping Li, Zhiwen Zhang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 346
The retention of therapeutic agents in solid tumors at sufficient concentration and duration is crucial for their antitumor effects. Given the important contribution of nanomedicines to oncology, we herein summarized two major strategies of nanomedic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8cd4b638a25eb7978c029b7b83622b6
https://pubmed.ncbi.nlm.nih.gov/35447297
https://pubmed.ncbi.nlm.nih.gov/35447297
Autor:
Xindi Qian, Guanru Wang, Jie Li, Xinyue Zhang, Minghui Zhang, Qingmin Yang, Zhiwen Zhang, Yaping Li
Publikováno v:
Journal of Drug Delivery Science and Technology. 75:103640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8356e640f34652b0f10322390e150311
https://doi.org/10.1016/j.jddst.2022.103640
https://doi.org/10.1016/j.jddst.2022.103640
Publikováno v:
Advanced Healthcare Materials. 11:2101428
The dense and heterogeneous physical network of the extracellular matrix (ECM) in tumors represents a formidable barrier that limits intratumor drug delivery and the therapeutic efficacy of many anticancer therapies. In this review, we summarize the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4802da8fb4e1661e1d685bec7995000
https://doi.org/10.1002/adhm.202101428
https://doi.org/10.1002/adhm.202101428