Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Xindao Zhang"'
Publikováno v:
Dose-Response, Vol 18 (2020)
S-Allyl cysteine (SAC), an organic compound and a natural constituent of Allium sativum , commonly known as garlic have been consumed in routine foods are known to possess various biological activities. Nevertheless, scientific evidence on the protec
Externí odkaz:
https://doaj.org/article/ebe9b0de1423497db4d4fc727acdacb1
Autor:
Liqun Chen, Alexander E. Aleshin, Gulimiran Alitongbieke, Yuqi Zhou, Xindao Zhang, Xiaohong Ye, Mengjie Hu, Gaoang Ren, Ziwen Chen, Yue Ma, Duo Zhang, Shuai Liu, Weiwei Gao, Lijun Cai, Lingjuan Wu, Zhiping Zeng, Fuquan Jiang, Jie Liu, Hu Zhou, Gregory Cadwell, Robert C. Liddington, Ying Su, Xiao-kun Zhang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
The transcription factor retinoid X receptor-alpha (RXRα) can also form homotetramers. Here the authors show that the anti-cancer agent K-80003 selectively inhibits the nongenomic action of N-terminally-cleaved RXRα in tumour cells by stabilizing i
Externí odkaz:
https://doaj.org/article/71d7bb2769b44bccb25ef396c7774a55
Autor:
Xiao-kun Zhang, Ying Su, Hu Zhou, Zhiping Zeng, Jie Liu, Meichun Gao, Dingyu Xu, Xindao Zhang, Liqun Chen, Zongxi Li, Shangjie Guo, Dan Xu, Meimei Yin, Ziwen Chen, Xiaotong Li, Zebin Xia, Gulimiran Alitongbieke, Xuhuang Tu, Xihua Cao, Xiaohui Chen
The Supplementary Methods show the Synthesis of DIM-C-pPhCF3+MeSO3- (BI1071); Figure S1 shows BI1071 induces apoptosis in different cancer cell lines; Fig. S2 shows BI1071 induces apoptosis in different breast cancer cell lines; Fig. S3 shows BI1071
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27184c0d2a83f59e3dbd0d6b2558ccf7
https://doi.org/10.1158/1535-7163.22504632.v1
https://doi.org/10.1158/1535-7163.22504632.v1
Autor:
Xiao-kun Zhang, Ying Su, Hu Zhou, Zhiping Zeng, Jie Liu, Meichun Gao, Dingyu Xu, Xindao Zhang, Liqun Chen, Zongxi Li, Shangjie Guo, Dan Xu, Meimei Yin, Ziwen Chen, Xiaotong Li, Zebin Xia, Gulimiran Alitongbieke, Xuhuang Tu, Xihua Cao, Xiaohui Chen
Nur77 (also called TR3 or NGFI-B), an orphan member of the nuclear receptor superfamily, induces apoptosis by translocating to mitochondria where it interacts with Bcl-2 to convert Bcl-2 from an antiapoptotic to a pro-apoptotic molecule. Nur77 posttr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a75517b87627ee1fd0766ac2d27be05
https://doi.org/10.1158/1535-7163.c.6537813.v1
https://doi.org/10.1158/1535-7163.c.6537813.v1
Autor:
Xiaohui Chen, Xuhuang Tu, Xindao Zhang, Bing Cao, Weirong Liu, Jie Zhang, Yongzhen Xia, Guoliang Bao, Dingyu Xu, Xiaokun Zhang, Zhiping Zeng, Ying Su
Publikováno v:
Bioorganic chemistry. 129
Nur77, an orphan nuclear receptor, is implicated in regulating diverse cellular biological processes including apoptosis and inflammation. We previously identified BI1071 (DIM-C-pPhCFsub3/subsup+/supMeSOsub3/subsup-/sup), an oxidized methanesulfonate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e029061446690c6755efc4fc79c8808
https://pubmed.ncbi.nlm.nih.gov/36179441
https://pubmed.ncbi.nlm.nih.gov/36179441
Autor:
Meimei Yin, Meichun Gao, Hu Zhou, Dan Xu, Zhiping Zeng, Ying Su, Shangjie Guo, Zebin Xia, Gulimiran Alitongbieke, Xiaotong Li, Xindao Zhang, Dingyu Xu, Xiaohui Chen, Xuhuang Tu, Xiao-kun Zhang, Zongxi Li, Ziwen Chen, Xihua Cao, Liqun Chen, Jie Liu
Publikováno v:
Mol Cancer Ther
Nur77 (also called TR3 or NGFI-B), an orphan member of the nuclear receptor superfamily, induces apoptosis by translocating to mitochondria where it interacts with Bcl-2 to convert Bcl-2 from an antiapoptotic to a pro-apoptotic molecule. Nur77 posttr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a3ed04c7087605bbb82e0bfb3bce16c
https://doi.org/10.1158/1535-7163.mct-18-0918
https://doi.org/10.1158/1535-7163.mct-18-0918
Publikováno v:
Dose-Response, Vol 18 (2020)
Dose-Response
Dose-Response
S-Allyl cysteine (SAC), an organic compound and a natural constituent of Allium sativum, commonly known as garlic have been consumed in routine foods are known to possess various biological activities. Nevertheless, scientific evidence on the protect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8632482365580c662bb432b6e32aea
https://doaj.org/article/ebe9b0de1423497db4d4fc727acdacb1
https://doaj.org/article/ebe9b0de1423497db4d4fc727acdacb1
Publikováno v:
Journal of Materials Science. 51:9296-9305
Hollow urchin-like NiCo2O4 microspheres were facilely synthesized by a simple hydrothermal approach combined with subsequent annealing process. The three-dimensional architectures with hollow structure are formed by the mechanism of the nanowires sel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0aed2fd051b85661e34b6f520a102874
https://doi.org/10.1007/s10853-016-0176-1
https://doi.org/10.1007/s10853-016-0176-1
Autor:
Xiu-Ming Li, Jian-Ming Li, Yuan-Yuan Zhao, Hua Wu, Xindao Zhang, Jing-Ru Wang, Yan-Bing Guo, Xiao-kun Zhang, Fuquan Jiang, Wen-Juan Gan, Xing-Xing Lu, Xiao-Shun He, Yao Liu
Publikováno v:
The Journal of Pathology. 238:457-469
Nur77, an immediate-early response gene, participates in a wide range of biological functions. Its human homologue, NUR77, is known by several names and has the HGNC-approved gene symbol NR4A1. However, the role of Nur77 in inflammatory bowel disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7f18d5032d7d68e900eb4e44d03bc5f7
https://doi.org/10.1002/path.4670
https://doi.org/10.1002/path.4670
Autor:
Jie Liu, Ying Su, Xinlei Shi, Yiming Xu, Yunxia Zhou, Xiao-kun Zhang, Lijun Cai, Minjun Meng, Fuquan Jiang, Hu Zhou, Yang Xu, Jing Wang, Gulimiran Alitongbieke, Xindao Zhang, Anshi Ren, Guanghui Wang, Zhiping Zeng, Lei Xie, Quan Cheng Chen
Publikováno v:
British Journal of Pharmacology. 173:344-356
Background and Purpose The orphan nuclear receptor Nur77 is implicated in the survival and apoptosis of cancer cells. The purpose of this study was to determine whether and how Nur77 serves to mediate the effect of the inflammatory cytokine TNF-α in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::858d5853a5bb4263d788345d253b4670
https://doi.org/10.1111/bph.13375
https://doi.org/10.1111/bph.13375