Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Xindan Xing"'
Autor:
Yihan Wang, Yujuan Liu, Junwei Fang, Xindan Xing, Hanying Wang, Xin Shi, Xinyi Liu, Tian Niu, Kun Liu
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-20 (2024)
Abstract Background Diabetes mellitus (DM) is a progressive disease that involves multiple organs due to increased blood glucose, and diabetic retinopathy (DR) is the main complication of DM in the eyes and causes irreversible vision loss. In the pat
Externí odkaz:
https://doaj.org/article/1a16abdf1a8d4b86be9c9f244232128b
Autor:
Xinyi Liu, Junwei Fang, Tian Niu, Xindan Xing, Xin Shi, Yu Xiao, Yuan Qu, Yan Jiang, Kangjia Lv, Tianyu Dou, Qian Zhu, Hancong Wan, Xiaoxin Liu, Hanying Wang, Kun Liu
Publikováno v:
Journal of Diabetes Research, Vol 2024 (2024)
Diabetic retinopathy (DR) is one of the most common complications of diabetes and induces severe visual impairment worldwide. Endothelial cell dysfunction plays an important role in the pathogenesis of DR. Here, we keep a watchful eye on α/β-hydrol
Externí odkaz:
https://doaj.org/article/5c0463e4dd7b44f6958d7fca2ef07a73
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction This study aims to determine whether high glucose condition and dynamic O-linked N-acetylglucosamine (O-GlcNAc) modification can promote the proliferation and migration of human retinal microvascular endothelial cells (HRMECs) and whethe
Externí odkaz:
https://doaj.org/article/31a637cdfb8b472497b0af2a97b4225b
Autor:
Xin Shi, Shaopin Zhu, Huiyi Jin, Junwei Fang, Xindan Xing, Yihan Wang, Hanying Wang, Chingyi Wang, Tian Niu, Kun Liu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Purpose: Adiponectin has been shown to exert potent anti-inflammatory activities in a range of systemic inflammatory diseases. This study aimed to investigate the potential therapeutic effects of KS23, a globular adiponectin-derived peptide, on endot
Externí odkaz:
https://doaj.org/article/2ce826702fcc4cff8566dabf3f3d9f5d
Autor:
Xindan Xing, Yan Jiang, Hanying Wang, Yuan Zhang, Tian Niu, Yuan Qu, Chingyi Wang, Haiyan Wang, Kun Liu
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 3, Pp n/a-n/a (2020)
Abstract Background The aim of this research was to investigate the retinal transcriptome changes in long‐term streptozotocin (STZ)‐induced rats' retinas using RNA sequencing (RNA‐seq), to explore the molecular mechanisms of diabetic retinopath
Externí odkaz:
https://doaj.org/article/434037486bcc4c869b75a914978b154c
Publikováno v:
Diabetes. 70:1185-1197
Diabetic retinopathy (DR) is the leading cause of acquired blindness in middle-aged people. The complex pathology of DR is difficult to dissect, given the convoluted cytoarchitecture of the retina. Here, we performed single-cell RNA sequencing (scRNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb30aaf2e3f247f16e2e736873f1358
https://doi.org/10.2337/db20-0839
https://doi.org/10.2337/db20-0839
Serum Ang-1/Ang-2 ratio may be a promising biomarker for evaluating severity of diabetic retinopathy
Autor:
Yihan Wang, Junwei Fang, Tian Niu, Xindan Xing, Hanying Wang, Xin Shi, Yujuan Liu, Xinyi Liu, Chong Chen, Kun Liu
Publikováno v:
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie.
To investigate the predictive role of serum angiopoietin-1 and angiopoietin-2 (Ang-1/Ang-2) in evaluating the severity of diabetic retinopathy (DR).A total of 101 outpatients with type 2 diabetes mellitus (T2DM) were recruited and were further divide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124b9ed09c31ea495b1129c95abc39c7
https://pubmed.ncbi.nlm.nih.gov/35838805
https://pubmed.ncbi.nlm.nih.gov/35838805
Publikováno v:
Archives of biochemistry and biophysics. 725
Diabetic retinopathy (DR) is the most common retinal microvascular disease caused by diabetes. Previous studies indicated that Pentraxin 3 (PTX3), an acute phase reactant, was closely related to the development of DR. But the exact effect of PTX3 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7289208a709cde6a8b0c27d7b6ed9f79
https://pubmed.ncbi.nlm.nih.gov/35577071
https://pubmed.ncbi.nlm.nih.gov/35577071
Publikováno v:
The FASEB Journal. 33:13346-13357
Endothelial glycocalyx plays a significant role in the development and progression of diabetic complications. Endomucin (EMCN) is an anti-inflammatory membrane glycoprotein that is mainly expressed in venous and capillary endothelial cells. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::450998ac21087fc8c42c5fbbf720175c
https://doi.org/10.1096/fj.201901161r
https://doi.org/10.1096/fj.201901161r
Publikováno v:
Biochemical and Biophysical Research Communications. 512:552-557
Purpose Angiogenesis is an essential part of the diabetes retinopathy (DR) process, and Zinc Finger RNA Binding Protein (ZFR) is important for vascularization to occur. However, the function and regulation of ZFR in DR development are not well unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3f83325d6dc6853bd40f97f09f69b46
https://doi.org/10.1016/j.bbrc.2019.03.135
https://doi.org/10.1016/j.bbrc.2019.03.135