Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Xinchi Jiang"'
Publikováno v:
Asian Journal of Pharmaceutical Sciences. Feb2024, Vol. 19 Issue 1, p1-17. 17p.
Autor:
Ting Huang, Ruyi Lin, Yuanqin Su, Hao Sun, Xixi Zheng, Jinsong Zhang, Xiaoyan Lu, Baiqin Zhao, Xinchi Jiang, Lingling Huang, Ni Li, Jing Shi, Xiaohui Fan, Donghang Xu, Tianyuan Zhang, Jianqing Gao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The use of exogenous mitochondria to replenish damaged mitochondria has been proposed as a strategy for the treatment of pulmonary fibrosis. However, the success of this strategy is partially restricted by the difficulty of supplying suffici
Externí odkaz:
https://doaj.org/article/423879c2cadb442f91cd65e219d67582
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 8, Pp 3215-3232 (2022)
The clinical translation of stem cells and their extracellular vesicles (EVs)-based therapy for central nervous system (CNS) diseases is booming. Nevertheless, the insufficient CNS delivery and retention together with the invasiveness of current admi
Externí odkaz:
https://doaj.org/article/fd5afb7b479944c5b12c186fb6539806
Peptide nano-blanket impedes fibroblasts activation and subsequent formation of pre-metastatic niche
Autor:
Yi Zhou, Peng Ke, Xiaoyan Bao, Honghui Wu, Yiyi Xia, Zhentao Zhang, Haiqing Zhong, Qi Dai, Linjie Wu, Tiantian Wang, Mengting Lin, Yaosheng Li, Xinchi Jiang, Qiyao Yang, Yiying Lu, Xincheng Zhong, Min Han, Jianqing Gao
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Primary tumors “spread the spark” by establishing a pre-metastatic niche. Here the authors develop an in-situ assembled peptide FR17 to serve as a “flame-retarding blanket” to extinguish the “fire” of the pre-metastatic microenvironment.
Externí odkaz:
https://doaj.org/article/3d8650ff2e364fc0b6121b19fcf14383
Autor:
Bo Zhao, Hangjuan Lin, Xinchi Jiang, Wanshu Li, Yuli Gao, Minghui Li, Yanan Yu, Ninggang Chen, Jianqing Gao
Publikováno v:
Theranostics; 2024, Vol. 14 Issue 12, p4598-4621, 24p
Publikováno v:
Cellular Physiology and Biochemistry, Vol 50, Iss 4, Pp 1255-1269 (2018)
Background/Aims: Genetic modification of mesenchymal stem cells (MSCs) is an essential requirement for their use as a delivery vehicle. To achieve higher transfection efficiency and better reproducibility than previously synthesized chitosan (100 kDa
Externí odkaz:
https://doaj.org/article/184a87060bae4f749f17194821033e80
Publikováno v:
Journal of Controlled Release. 350:107-121
Rheumatoid arthritis (RA) is a joint-related autoimmune disease that is difficult to cure. Most therapeutics act to alleviate the symptoms but not correct the causes of RA. Novel strategies that specifically target the causes are highly needed for RA
Autor:
Honghui Wu, Xinchi Jiang, Yaosheng Li, Yunfei Dong, Juanjuan Zheng, Lu Li, Ying Li, Jinqiang Wang, Xianming Lin, Xiangnan Zhang, Tianyuan Zhang, Zhen Gu, Jianqing Gao
Publikováno v:
Nano Today. 49:101800
Autor:
Ruyi Lin, Hao Sun, Jiafu Mu, Ting Huang, Dong-Hang Xu, Hongcui Cao, Jian-Qing Gao, Daishun Ling, Yuanqin Su, Honghui Wu, Xinchi Jiang, Ai Li, Xiaoyi Sun, Tian-Yuan Zhang
Publikováno v:
Theranostics
Background: Mesenchymal stem cells (MSCs) have been applied as a promising vehicle for tumour-targeted delivery of suicide genes in the herpes simplex virus thymidine kinase (HSV-tk)/ganciclovir (GCV) suicide gene therapy against malignant gliomas. T
Autor:
Ruyi Lin, Ni Li, Yasuhiko Tabata, Jian-Qing Gao, Qiong Bian, Tian-Yuan Zhang, Honghui Wu, Yuanqin Su, Xinchi Jiang, Ting Huang, Jinqiang Wang, Daishun Ling, Hongcui Cao, Ai Li, Zhen Gu
Publikováno v:
Science Advances
Description
Iron oxide nanoparticles could significantly promote the mitochondrial transfer from mesenchymal stem cells to the injured cells.
The transfer of mitochondria between cells has recently been revealed as a spontaneous way to prot
Iron oxide nanoparticles could significantly promote the mitochondrial transfer from mesenchymal stem cells to the injured cells.
The transfer of mitochondria between cells has recently been revealed as a spontaneous way to prot