Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Xincan Li"'
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0251323 (2021)
The recent advances in gene chip technology have led to the identification of multiple metabolism-related genes that are closely associated with colorectal cancer (CRC). Nevertheless, none of these genes could accurately diagnose or predict CRC. The
Externí odkaz:
https://doaj.org/article/0c21b5c628eb4dfbb0905e5e599949de
Autor:
Shengwen Zhou, Xincan Li, Yunjiao Lüli, Xuan Li, Zuo H. Chen, Pengcheng Yuan, Zhu L. Yang, Guohong Li, Hong Luo
Publikováno v:
Journal of Fungi, Vol 7, Iss 3, p 204 (2021)
Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind. Thes
Externí odkaz:
https://doaj.org/article/6e8d43433cb1440895960920995d451b
Publikováno v:
Marine Drugs, Vol 18, Iss 4, p 180 (2020)
α-Conotoxin TxIB specifically blocked α6/α3β2β3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to α6/α3β2β3 nAChRs. However, as a peptide, TxIB may suffer from low stabil
Externí odkaz:
https://doaj.org/article/c75fa722c2c540b4b9c159199027d8df
Autor:
Sulan Luo, Peta J. Harvey, Yong Wu, Xiaopeng Zhu, Pan Xu, Xincan Li, David J. Craik, Quentin Kaas, Dongting Zhangsun
Publikováno v:
Journal of Medicinal Chemistry. 63:1564-1575
αO-conotoxin GeXIVA from Conus generalis is a potent antagonist of the α9α10 nAChR and analgesic in animal models of pain. This peptide has two disulfide bond cross-links, and the bead and ribbon isomers have similar inhibitory activity against α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b365d8093aba768b92cc6805bb12382
https://doi.org/10.1021/acs.jmedchem.9b01409
https://doi.org/10.1021/acs.jmedchem.9b01409
Autor:
Xincan Li
Publikováno v:
The 2021 International Conference on Machine Learning and Big Data Analytics for IoT Security and Privacy ISBN: 9783030895075
In the current era of deepening financial openness, with the development of big data in computer finance, the vigorous development of fintech has brought “technology spillover effect” and “competition effect” to the risks of banks. Computer b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee4f529a471a104d484d96efc72b5429
https://doi.org/10.1007/978-3-030-89508-2_57
https://doi.org/10.1007/978-3-030-89508-2_57
Autor:
Jiemei Jiang, Yuanyuan Tian, Xincan Li, Danrui Liu, Yong Wu, Sulan Luo, Ying Fu, Rui Li, Donting Zhangsun
Publikováno v:
Journal of Molecular Graphics and Modelling. 92:55-64
The α9α10 nicotinic acetylcholine receptor (nAChR) is an effective therapeutic target for neuropathic pain. α-Conotoxin RgIA and Vc1.1 are two well-known peptides blocking α9α10 nAChR potently and selectively, which have been extensively investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ecf8e32c9f2a679643d4bec3da25b83
https://doi.org/10.1016/j.jmgm.2019.06.020
https://doi.org/10.1016/j.jmgm.2019.06.020
Autor:
Zuo H. Chen, Yunjiao Lüli, Guo-Hong Li, Hong Luo, Pengcheng Yuan, Xuan Li, Zhu L. Yang, Xincan Li, Shengwen Zhou
Publikováno v:
Journal of Fungi, Vol 7, Iss 204, p 204 (2021)
Journal of Fungi
Volume 7
Issue 3
Journal of Fungi
Volume 7
Issue 3
Most species in the genus Amanita are ectomycorrhizal fungi comprising both edible and poisonous mushrooms. Some species produce potent cyclic peptide toxins, such as α-amanitin, which places them among the deadliest organisms known to mankind. Thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb983cc50d13bcb87000c1228fe9e4ee
https://www.mdpi.com/2309-608X/7/3/204
https://www.mdpi.com/2309-608X/7/3/204
Publikováno v:
Bioorganic chemistry. 112
Head-to-tail cyclization is an effective strategy to improve the biological stability of peptides. The α-conotoxin [S9A]TxID is a peptide that inhibits α3β4 nAChR with high activity and selectivity. Herein, we established a method for cyclizing an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60a0b7c3ed94010f0bf7cd6eb582e5d5
https://pubmed.ncbi.nlm.nih.gov/33823404
https://pubmed.ncbi.nlm.nih.gov/33823404
Publikováno v:
Marine Drugs
Volume 18
Issue 4
Marine Drugs, Vol 18, Iss 180, p 180 (2020)
Volume 18
Issue 4
Marine Drugs, Vol 18, Iss 180, p 180 (2020)
&alpha
Conotoxin TxIB specifically blocked &alpha
6/&alpha
3&beta
2&beta
3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to &alpha
3 nAChRs. However
Conotoxin TxIB specifically blocked &alpha
6/&alpha
3&beta
2&beta
3 acetylcholine receptors (nAChRs), and it could be a potential probe for studying addiction and other diseases related to &alpha
3 nAChRs. However
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fb0286571adf3f2fb7d53c17585ab74
Background: Most species in the genus Amanita are ectomycorrhizal fungi, and the cyclic peptide toxins that some species produce are notoriously deadly. In total, around 25 of these peptides were found in the fruiting bodies over the past 82 years, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c5c2df752b4c0c0296b636a1dd3366c
https://doi.org/10.21203/rs.2.23821/v1
https://doi.org/10.21203/rs.2.23821/v1