Zobrazeno 1 - 10
of 182
pro vyhledávání: '"XinRan Ma"'
Autor:
Liang Dong, Zhi Cao, Meixia Chen, Yang Liu, Xinran Ma, Yuting Lu, Yan Zhang, Kaichao Feng, Yang Zhang, Zhenzhen Meng, Qingming Yang, Yao Wang, Zhiqiang Wu, Weidong Han
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Glycosphingolipids (GSLs) are abundantly expressed in cancer cells. The effects of GSL-targeted immunotherapies are not fully understood. Here, we show that the inhibition of GSL synthesis with the UDP-glucose ceramide glucosyltransferase in
Externí odkaz:
https://doaj.org/article/f1f59b5fd14c41e1be35dc4dca134cea
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-7 (2024)
Abstract Vibrio spp. are major pathogens responsible for mortality and disease in various marine aquaculture organisms. Effective disease control and genetic breeding strategies rely heavily on understanding host vibriosis resistance mechanisms. The
Externí odkaz:
https://doaj.org/article/34b37b7e19024802bc5801fdeb9f5c9e
Autor:
Wenjuan Wu, Hongxia Jia, Song Chen, Xinran Ma, Shuai Zhou, Lingxiao Qiu, Xinhui Wu, Ping Li, Heying Chu, Guojun Zhang
Publikováno v:
Molecular Medicine, Vol 30, Iss 1, Pp 1-13 (2024)
Abstract Background 8-Oxoguanine DNA glycosylase (OGG1), a well-known DNA repair enzyme, has been demonstrated to promote lung fibrosis, while the specific regulatory mechanism of OGG1 during pulmonary fibrosis remains unclarified. Methods A bleomyci
Externí odkaz:
https://doaj.org/article/2fd6ead026ca4ccb9170ab0f0ca8314c
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundParkinson’s disease (PD) is a common neurodegenerative disorder that affects motor and non-motor functions, significantly reducing patients’ quality of life. No effective drug-based treatments are known to solve this problem. Non-drug t
Externí odkaz:
https://doaj.org/article/984297755cd84006b83e17f74c896e10
Autor:
Yi Zhang, Liwei Chen, Ye Xuan, Lina Zhang, Wen Tian, Yangyang Zhu, Jinghui Wang, Xinyu Wang, Jin Qiu, Jian Yu, Mengyang Tang, Zhen He, Hong Zhang, Si Chen, Yun Shen, Siyi Wang, Rong Zhang, Lingyan Xu, Xinran Ma, Yunfei Liao, Cheng Hu
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113900- (2024)
Summary: Iron overload is closely associated with metabolic dysfunction. However, the role of iron in the hypothalamus remains unclear. Here, we find that hypothalamic iron levels are increased, particularly in agouti-related peptide (AgRP)-expressin
Externí odkaz:
https://doaj.org/article/113970000ab24969ac0cd5665c0aa046
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/89d8ad13dfd347f9a8adc294803f4123
Autor:
Xinming Xu, Jin Qiu, Xiaoya Li, Juntong Chen, Yue Li, Xinmei Huang, Shufei Zang, Xinran Ma, Jun Liu
Publikováno v:
Nutrition & Metabolism, Vol 20, Iss 1, Pp 1-14 (2023)
Abstract Background Non-alcoholic steatohepatitis (NASH) is a major contributor to liver cirrhosis and hepatocellular carcinoma. There remains no effective pharmacological therapy. The hepatic lipid metabolism and fatty acid β-oxidation are regulate
Externí odkaz:
https://doaj.org/article/d117a15677b845239cfbf4574ec9d708
Autor:
Guoqiang Li, Lijun Zhu, Mingwei Guo, Dongmei Wang, Meiyao Meng, Yinzhao Zhong, Zhijian Zhang, Yi Lin, Caizhi Liu, Jiawen Wang, Yahui Zhang, Yining Gao, Yuxiang Cao, Zhirui Xia, Jin Qiu, Yu Li, Shuang Liu, Haibing Chen, Wenyue Liu, Yu Han, Minghua Zheng, Xinran Ma, Lingyan Xu
Publikováno v:
JHEP Reports, Vol 5, Iss 12, Pp 100906- (2023)
Background & Aims: Liver regeneration is vital for the recovery of liver function after injury, yet the underlying mechanism remains to be elucidated. Forkhead box protein A3 (FOXA3), a member of the forkhead box family, plays important roles in endo
Externí odkaz:
https://doaj.org/article/610a395a4a944b73beda4066a3ff902c
Autor:
Mingwei Guo, Jing Yao, Jin Li, Jun Zhang, Dongmei Wang, Hui Zuo, Yi Zhang, Bo Xu, Yinzhao Zhong, Fei Shen, Jian Lu, Shuzhe Ding, Cheng Hu, Lingyan Xu, Junjie Xiao, Xinran Ma
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 1, Pp 391-405 (2023)
Abstract Background Age‐associated sarcopenia is characterized of progressed loss of skeletal muscle power, mass, and function, which affects human physical activity and life quality. Besides, accompanied with sarcopenia, aged population also faces
Externí odkaz:
https://doaj.org/article/f1801bc1fcbb47b0914afdf6951006ad
Autor:
Lynne L. Johnson, Yared Tekabe, Tina Zelonina, Xinran Ma, Geping Zhang, Monica Goldklang, Jeanine D’Armiento
Publikováno v:
Respiratory Research, Vol 24, Iss 1, Pp 1-9 (2023)
Abstract Background Receptor for Advanced Glycated Endproducts (RAGE) plays a major role in the inflammatory response to infectious and toxin induced acute lung injury. We tested the hypothesis that a RAGE blocking antibody when administered after th
Externí odkaz:
https://doaj.org/article/9e56016543cd44bcb29de07ea132b0bf