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Akademický článek

Nogo-B mediates endothelial oxidative stress and inflammation to promote coronary atherosclerosis in pressure-overloaded mouse hearts

Autor: Yu Zhang, Jing-Jing Li, Rui Xu, Xin-Pei Wang, Xin-Yi Zhao, Yuan Fang, Yu-Peng Chen, Shan Ma, Xiao-Hui Di, Wei Wu, Gang She, Zheng-Da Pang, Yi-Dong Wang, Xing Zhang, Wenjun Xie, Xiu-Ling Deng, Xiao-Jun Du, Yi Zhang

Publikováno v: Redox Biology, Vol 68, Iss , Pp 102944- (2023)

Aims: Endothelial dysfunction plays a pivotal role in atherosclerosis, but the detailed mechanism remains incomplete understood. Nogo-B is an endoplasmic reticulum (ER)-localized protein mediating ER-mitochondrial morphology. We previously showed end

Externí odkaz: https://doaj.org/article/66907925c4c1495da7a001e602e430cf

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Akademický článek

AGEs-RAGE-KCa3.1 pathway mediates palmitic acid-induced migration of PBMCs from patients with type 2 diabetes

Autor: Yi Zhang, Xiao-Zhen Ma, Xin-Yi Zhao, Jing-Jing Li, Shan Ma, Zheng-Da Pang, Jing Xu, Xiao-Jun Du, Xiu-Ling Deng, Jun-Hong Wang

Publikováno v: Heliyon, Vol 9, Iss 4, Pp e14823- (2023)

Type 2 diabetes mellitus (T2DM) is characterized by chronic low-grade systemic inflammation. Tissue infiltration by monocyte migration contributes to the pathogenesis of vascular complications in T2DM. We studied the role of intermediate-conductance

Externí odkaz: https://doaj.org/article/fa0d579649c7403cbc02094a04ce163a

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Akademický článek

Application and progress of palliative therapy in advanced gastric carcinomas

Autor: Xiao-fan Luo, Ye-hao Luo, Xin-yi Zhao, Xue-ting Lin, Wen-ling Li, Jie Jie, Di Wu, Gang Fang, Yu-zhou Pang, An Huang

Publikováno v: Frontiers in Oncology, Vol 13 (2023)

Gastric carcinomas have high morbidity and mortality. It produces no noticeable symptoms in the early stage while causing complex complications in its advanced stage, making treatment difficult. Palliative therapy aims to relieve the symptoms of canc

Externí odkaz: https://doaj.org/article/74029cd18dc4471b86a1a64424fc0e1f

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Akademický článek

Arsenic contamination caused by roxarsone transformation with spatiotemporal variation of microbial community structure in a column experiment

Autor: Ya-ci Liu, Zhao-ji Zhang, Xin-yi Zhao, Meng-tuo Wen, Sheng-wei Cao, Ya-song Li

Publikováno v: Journal of Groundwater Science and Engineering, Vol 9, Iss 4, Pp 304-316 (2021)

Arsenic contamination from roxarsone in livestock manure is common, and livestock manure continuously accumulates in the open environment. Evaluations of the environmental processes of As mobilization and transformation are critical for predicting th

Externí odkaz: https://doaj.org/article/3a266e9abf504f2990dc041391e68075

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Akademický článek

Spectroscopic Studies of Delafloxacin Meglumine

Autor: Xin-yi ZHAO, Dong HAN, Hong-jun LUO, Wen-bin SHEN, Gong-jun YANG

Publikováno v: Chinese Journal of Magnetic Resonance, Vol 38, Iss 2, Pp 268-276 (2021)

The structure of delafloxacin meglumine was analyzed by infrared absorption (IR), ultraviolet absorption (UV), nuclear magnetic resonance (1H NMR, 13C NMR, DEPT, 1H-1H COSY, 1H-13C HSQC and 1H-13C HMBC) spectroscopy, mass spectrometry and elemental a

Externí odkaz: https://doaj.org/article/1e54ab16061d4d5691fb3875ed8ba40f

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Akademický článek

Risks of specific congenital anomalies in offspring of women with diabetes: A systematic review and meta-analysis of population-based studies including over 80 million births

Autor: Tie-Ning Zhang, Xin-Mei Huang, Xin-Yi Zhao, Wei Wang, Ri Wen, Shan-Yan Gao

Publikováno v: PLoS Medicine, Vol 19, Iss 2 (2022)

Background Pre-gestational diabetes mellitus (PGDM) has been known to be a risk factor for congenital heart defects (CHDs) for decades. However, the associations between maternal PGDM and gestational diabetes mellitus (GDM) and the risk of specific t

Externí odkaz: https://doaj.org/article/50eab0db322340ae91c337f92784027e

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Akademický článek

Hippocampal PPARα Plays a Role in the Pharmacological Mechanism of Vortioxetine, a Multimodal-Acting Antidepressant

Autor: Yuan Wang, Jiang-Hong Gu, Ling Liu, Yue Liu, Wen-Qian Tang, Chun-Hui Ji, Wei Guan, Xin-Yi Zhao, Ying-Fang Sun, Da-Wei Xu, Bo Jiang

Publikováno v: Frontiers in Pharmacology, Vol 12 (2021)

As a well-known multimodal-acting antidepressant, vortioxetine is thought to aim at several serotonin (5-HT) receptors and the 5-HT transporter. However, recently more and more proteins besides 5-HT are being reported to participate in the antidepres

Externí odkaz: https://doaj.org/article/dc065ff7d8b646a39507e9e5dcd391dd

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Endothelial K Ca 3.1 and K Ca 2.3 Mediate S1P (Sphingosine-1-Phosphate)–Dependent Vasodilation and Blood Pressure Homeostasis

Autor: Jing-Jing Li, Xin-Yi Zhao, Yan Wang, Rui Xu, Xiao-Hui Di, Yu Zhang, Hongyan Yang, Meng-Zhuan Han, Ru-Yue Bai, Lin Xie, Zheng-Da Pang, Xing Zhang, Jianbao Zhang, Xiao-Jun Du, Xiu-Ling Deng, Yi Zhang, Wenjun Xie

Publikováno v: Arteriosclerosis, Thrombosis, and Vascular Biology. 43:726-738

Background: S1P (sphingosine-1-phosphate) has been reported to possess vasodilatory properties, but the underlying pathways are largely unknown. Methods: Isolated mouse mesenteric artery and endothelial cell models were used to determine S1P-induced

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e564d019528c61183af463a4a48677b8
https://doi.org/10.1161/atvbaha.122.318820

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