Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Xin-xin Hu"'
Autor:
Na Zhao, Ying-Ying Li, Jia-Man Xu, Mu-Yao Yang, Yun-Zhe Li, Thomas Chuen Lam, Lei Zhou, Qi-Hu Tong, Jun-Tao Zhang, Sheng-Zhan Wang, Xin-Xin Hu, Yu-Fei Wu, Qin-Kang Lu, Ting-Yuan Lang
Publikováno v:
International Journal of Ophthalmology, Vol 17, Iss 11, Pp 1995-2006 (2024)
AIM: To investigate the proliferation regulatory effect of cone-rod homeobox (CRX) in retinal pigment epithelium (RPE) and retinoblastoma (RB) cells to explore the potential application and side effect (oncogenic potential) of CRX-based gene therapy
Externí odkaz:
https://doaj.org/article/2a0dadeeaf38484497f341a584f155c7
Autor:
Wei-hong Chen, Shao-rong Chen, Xin-xin Hu, Qiao-yi Huang, Jia-ming Chen, Shu Lin, Qi-yang Shi
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22902- (2023)
Background: Intrauterine adhesion (IUA) results from serious complications of intrauterine surgery or infection and mostly remains incurable. Small extracellular vesicles (sEVs) derived from mesenchymal stem cells (MSCs) have emerged as a potential n
Externí odkaz:
https://doaj.org/article/827d8e01093c49df9a23e8acd8f05a12
Autor:
Wei Ou, Ning Li, Bao-Xiao Wang, Teng-Fei Zhu, Zhi-Lin Shen, Tao Wang, Wu-Guang Chang, Zeng-Hao Chang, Xin-Xin Hu, Yue Pu, Lie-Ming Ding, Si-Yu Wang
Publikováno v:
EClinicalMedicine, Vol 57, Iss , Pp 101839- (2023)
Summary: Background: This phase 2 trial aimed to compare adjuvant icotinib with observation in patients with epidermal growth factor receptor (EGFR) mutation-positive resected stage IB non-small cell lung cancer (NSCLC). Methods: We performed a rando
Externí odkaz:
https://doaj.org/article/9e562c6ce44244e7aa3c95ec663fc131
Autor:
Xin-Xin Hu, Zhu-Bo Wang, Pengfei Zhang, Guang-Jie Chen, Yan-Lei Zhang, Gang Li, Xu-Bo Zou, Tiancai Zhang, Hong X. Tang, Chun-Hua Dong, Guang-Can Guo, Chang-Ling Zou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Optical nonreciprocity through magneto-optical effects requires bulky apparatuses and strong magnetic fields, while magnetic-free approaches are difficult to implement. Here, the authors use optically-induced magnetisation in an atomic ensemble to ge
Externí odkaz:
https://doaj.org/article/5dc898a5a4be43c2887858ac23bf6761
Autor:
Sen He, Hong-Tong Chen, Rui Zhao, Xin-Xin Hu, Tong-Ying Nie, Xin-Yi Yang, Cong-Ran Li, Xi Lu, Xiu-Kun Wang, Xue Li, Yun Lu, Guo-Qing Li, Jing Pang, Xue-Fu You
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228797 (2020)
(E)-N,N-dimethyl-4-oxo-4-(4-(pyridin-4-yl)phenyl)but-2-enamide hydrochloride (IMB-YH-4py5-2H) is a novel Protein Kinase B (PknB) inhibitor with potent activity against Mycobacterium tuberculosis strains. In the present study, a sensitive and specific
Externí odkaz:
https://doaj.org/article/f88179852fef4b1f89c1248e782d5140
Autor:
Rui Zhao, Qing Wang, Xin-Xin Hu, Tong-Ying Nie, Xin-Yi Yang, Cong-Ran Li, Xi Lu, Xiukun Wang, Jian-Dong Jiang, Jing Pang, Xue-Fu You
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0217573 (2019)
Pharmacological efficacy is based on the drug concentration in target tissues, which usually cannot be represented by the plasma concentration. The purpose of this study was to compare the pharmacokinetic characteristics of gemifloxacin in plasma and
Externí odkaz:
https://doaj.org/article/6118eb304a9b4b41a8899fd54334fc70
Autor:
Yuan-Shuai Yang, Wei Wei, Xin-Xin Hu, Sheng Tang, Jing Pang, Xue-Fu You, Tian-Yun Fan, Yan-Xiang Wang, Dan-Qing Song
Publikováno v:
Molecules, Vol 24, Iss 5, p 984 (2019)
Twenty-five new derivatives of 8-hydroxycycloberberine (1) were synthesized and evaluated for their activities against Gram-positive bacteria, taking 1 as the lead. Part of them displayed satisfactory antibacterial activities against methicillin-susc
Externí odkaz:
https://doaj.org/article/404eb427fe1f4bf78764ded5459bdc75
Autor:
Hai-Gen Fu, Zhi-Wen Li, Xin-Xin Hu, Shu-Yi Si, Xue-Fu You, Sheng Tang, Yan-Xiang Wang, Dan-Qing Song
Publikováno v:
Molecules, Vol 24, Iss 3, p 548 (2019)
Nineteen new quinoline derivatives were prepared via the Mannich reaction and evaluated for their antibacterial activities against both Gram-positive (G+) and Gram-negative (G−) bacteria, taking compound 1 as the lead. Among the target compounds, q
Externí odkaz:
https://doaj.org/article/a238814f0cd74419b1fda50ae29cd583
Autor:
Wei Shi, Si Wei, Xin-Xin Hu, Guan-Jiu Hu, Cu-Lan Chen, Xin-Ru Wang, John P Giesy, Hong-Xia Yu
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e73883 (2013)
Some synthetic chemicals, which have been shown to disrupt thyroid hormone (TH) function, have been detected in surface waters and people have the potential to be exposed through water-drinking. Here, the presence of thyroid-active chemicals and thei
Externí odkaz:
https://doaj.org/article/d3336d34a48443aea52ca09e48ff7c48
Autor:
Xiu-Kun Wang, Jie Yu, Chun-Yang Xie, Xin-Xin Hu, Tong-Ying Nie, Xue Li, Peng-He Wang, Guo-Qing Li, Hong Yuan, Xin-Yi Yang, Cong-Ran Li, Xue-Fu You
Publikováno v:
Journal of Antimicrobial Chemotherapy.
Objectives Contezolid acefosamil is a novel O-acyl phosphoramidate prodrug of contezolid. In the current study, we aimed to systemically evaluate the efficacy of contezolid acefosamil against infections caused by multiple Gram-positive pathogens, and