Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Xin-xiang Yan"'
Autor:
Hong-xu Pan, Yu-wen Zhao, Jun-pu Mei, Zheng-huan Fang, Yige Wang, Xun Zhou, Yang-jie Zhou, Rui Zhang, Kai-lin Zhang, Li Jiang, Qian Zeng, Yan He, Zheng Wang, Zhen-hua Liu, Qian Xu, Qi-ying Sun, Yang Yang, Ya-cen Hu, Ya-se Chen, Juan Du, Li-fang Lei, Hai-nan Zhang, Chun-yu Wang, Xin-xiang Yan, Lu Shen, Hong Jiang, Jie-qiong Tan, Jin-chen Li, Bei-sha Tang, Ji-feng Guo
Publikováno v:
Translational Neurodegeneration, Vol 9, Iss 1, Pp 1-12 (2020)
Abstract Background Common and rare variants of guanosine triphosphate cyclohydrolase 1 (GCH1) gene may play important roles in Parkinson’s disease (PD). However, there is a lack of comprehensive analysis of GCH1 genotypes, especially in non-coding
Externí odkaz:
https://doaj.org/article/e37c50f7cbe541038d65d3dfff802d0e
Autor:
Kun Xu, Xiao-xia Zhou, Run-cheng He, Zhou Zhou, Zhen-hua Liu, Qian Xu, Qi-ying Sun, Xin-xiang Yan, Xin-yin Wu, Ji-feng Guo, Bei-sha Tang
Publikováno v:
Frontiers in Neurology, Vol 12 (2021)
Objectives: Although risk factors for freezing of gait (FOG) have been reported, there are still few prediction models based on cohorts that predict FOG. This 1-year longitudinal study was aimed to identify the clinical measurements closely linked wi
Externí odkaz:
https://doaj.org/article/c5641e2b1a214107b0ee75c7c076b847
Autor:
Yu-wen Zhao, Hong-xu Pan, Zhenhua Liu, Yige Wang, Qian Zeng, Zheng-huan Fang, Teng-fei Luo, Kun Xu, Zheng Wang, Xun Zhou, Runcheng He, Bin Li, Guihu Zhao, Qian Xu, Qi-ying Sun, Xin-xiang Yan, Jie-qiong Tan, Jin-chen Li, Ji-feng Guo, Bei-sha Tang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Background: Recent years have witnessed an increasing number of studies indicating an essential role of the lysosomal dysfunction in Parkinson’s disease (PD) at the genetic, biochemical, and cellular pathway levels. In this study, we investigated t
Externí odkaz:
https://doaj.org/article/e91aa4c6c749496789aa5c4675283a09
Autor:
Ji-feng Guo, Ling-yan Yao, Qi-ying Sun, Yi-ting Cui, Yang Yang, Qian Xu, Xin-xiang Yan, Bei-sha Tang
Publikováno v:
Translational Neurodegeneration, Vol 6, Iss 1, Pp 1-9 (2017)
Abstract Background PINK1 (PTEN-induced putative kinase 1) gene is the causal gene for recessive familial type 6 of Parkinson’s disease (PARK6), which is an early-onset autosomal recessive inherited neurodegenerative disease. PINK1 has been reporte
Externí odkaz:
https://doaj.org/article/a5eba3fc88174dd1b47c0fcd8e54620c
Autor:
Ya-qin Xiang, Qian Xu, Qi-ying Sun, Zhi-qin Wang, Yun Tian, Liang-juan Fang, Yang Yang, Jie-qiong Tan, Xin-xiang Yan, Bei-sha Tang, Ji-feng Guo
Publikováno v:
Frontiers in Neurology, Vol 10 (2019)
Objective: To explore the clinical features and correlates of excessive daytime sleepiness (EDS) in a Chinese population of Parkinson's disease (PD) patients.Methods: Patients with clinically established or clinically probable PD were recruited. Clin
Externí odkaz:
https://doaj.org/article/052262e2dcb245b2b211671868ef7fb9
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 13, Iss 7, Pp 587-595 (2013)
Background DJ⁃1 gene is a causative gene which contributes to the onset of autosomal recessive early-onset parkinsonism (AREP). Many research suggest that DJ-1 protein may change expression of certain genes through regulate its transcriptional acti
Externí odkaz:
https://doaj.org/article/3bfde9523d5e4c2fbdcd21dec7e8f1d7
Autor:
Yuan Zhang, Qi-ying Sun, Yu-wen Zhao, Li Shu, Ji-feng Guo, Qian Xu, Xin-xiang Yan, Bei-sha Tang
Publikováno v:
Parkinson's Disease, Vol 2015 (2015)
GBA has been identified as a genetic risk factor for PD. Whether the clinical manifestations of PD patients with or without GBA mutations are different has still not reached a consensus. We firstly detected the GBA mutation L444P in 1147 Chinese PD p
Externí odkaz:
https://doaj.org/article/086ff24b086e4388898a951604ba17c9
Autor:
Zhan-fang Sun, Yu-han Zhang, Ji-feng Guo, Qi-ying Sun, Jun-pu Mei, Han-lin Zhou, Li-ping Guan, Jin-yong Tian, Zheng-mao Hu, Jia-da Li, Kun Xia, Xin-xiang Yan, Bei-sha Tang
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106388 (2014)
Dopa-responsive dystonia, a rare disorder typically presenting in early childhood with lower limb dystonia and gait abnormality, responds well to levodopa. However, it is often misdiagnosed with the wide spectrum of phenotypes. By exome sequencing, w
Externí odkaz:
https://doaj.org/article/5a3845f214574d7989c12c8fb6c74c8f
Autor:
Yan Qin, Runcheng He, Juan Chen, Xiaoxia Zhou, Xun Zhou, Zhenhua Liu, Qian Xu, Ji-Feng Guo, Xin-Xiang Yan, Nana Jiang, Weihua Liao, Toshiaki Taoka, Dongcui Wang, Beisha Tang
Publikováno v:
Journal of Neurology. 270:2649-2658
Autor:
Li-zhi Li, Yu-wen Zhao, Hong-xu Pan, Ya-qin Xiang, Yi-ge Wang, Qian Xu, Xin-xiang Yan, Jie-qiong Tan, Jin-chen Li, Bei-sha Tang, Ji-feng Guo
Publikováno v:
Journal of Human Genetics. 67:687-690