Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Xin-jie Guan"'
Autor:
Ashok Iyaswamy, Abhimanyu Thakur, Xin-Jie Guan, Senthilkumar Krishnamoorthi, Tsz Yan Fung, Kejia Lu, Isha Gaurav, Zhijun Yang, Cheng-Fu Su, Kwok-Fai Lau, Kui Zhang, Roy Chun-Laam Ng, Qizhou Lian, King-Ho Cheung, Keqiang Ye, Huanhuan Joyce Chen, Min Li
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-14 (2023)
Abstract Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by the predominant impairment of neurons in the hippocampus and the formation of amyloid plaques, hyperphosphorylated tau protein, and neurofibrillary tangles in the br
Externí odkaz:
https://doaj.org/article/6b764bb85ea2452a913aa80974bdc655
Autor:
Sravan Gopalkrishnashetty Sreenivasmurthy, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Rambabu N. Reddi, Ananth Kumar Kammala, Karthick Vasudevan, Sanjib Senapati, Zhou Zhu, Cheng-Fu Su, Jia Liu, Xin-Jie Guan, Ka-Kit Chua, King-Ho Cheung, Hubiao Chen, Hong-Jie Zhang, Yuan Zhang, Ju-Xian Song, Siva Sundara Kumar Durairajan, Min Li
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Emerging evidence from Alzheimer’s disease (AD) patients suggests that reducing tau pathology can restore cognitive and memory loss. To reduce tau pathology, it is critical to find brain-permeable tau-degrading small molecules that are safe and eff
Externí odkaz:
https://doaj.org/article/ad4864ffb5f248789897756ed41a5785
Autor:
Ashok Iyaswamy, Kejia Lu, Xin-Jie Guan, Yuxuan Kan, Chengfu Su, Jia Liu, Ravindran Jaganathan, Karthick Vasudevan, Jeyakumari Paul, Abhimanyu Thakur, Min Li
Publikováno v:
Biomedicines, Vol 11, Iss 7, p 2056 (2023)
Bacterial Extracellular Vesicles (BEVs) possess the capability of intracellular interactions with other cells, and, hence, can be utilized as an efficient cargo for worldwide delivery of therapeutic substances such as monoclonal antibodies, proteins,
Externí odkaz:
https://doaj.org/article/e0d8b1fd825748a1bfc2ed5f40939f67
Autor:
Tsz Yan Fung, Ashok Iyaswamy, Sravan G. Sreenivasmurthy, Senthilkumar Krishnamoorthi, Xin-Jie Guan, Zhou Zhu, Cheng-Fu Su, Jia Liu, Yuxuan Kan, Yuan Zhang, Hoi Leong Xavier Wong, Min Li
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 705 (2022)
Alzheimer’s disease (AD) is an age-associated neurodegenerative disease; it is the most common cause of senile dementia. Klotho, a single-pass transmembrane protein primarily generated in the brain and kidney, is active in a variety of metabolic pa
Externí odkaz:
https://doaj.org/article/1b1ee19d421e4d44841f952fcacca5b4
Autor:
Zhou Zhu, Liang-feng Liu, Cheng-fu Su, Jia Liu, Benjamin Chun-Kit Tong, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Sravan Gopalkrishnashetty Sreenivasmurthy, Xin-jie Guan, Yu-xuan Kan, Wen-jian Xie, Chen-liang Zhao, King-ho Cheung, Jia-hong Lu, Jie-qiong Tan, Hong-jie Zhang, Ju-xian Song, Min Li
Publikováno v:
Acta Pharmacologica Sinica. 43:2511-2526
Increasing evidence shows that autophagy impairment is involved in the pathogenesis and progression of neurodegenerative diseases including Parkinson's disease (PD). We previously identified a natural alkaloid named corynoxine B (Cory B) as a neurona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78fe304481ce9fb652f0dcbafd19d223
https://doi.org/10.1038/s41401-022-00871-0
https://doi.org/10.1038/s41401-022-00871-0
Autor:
Zi-Ying Wang, Ashok Iyaswamy, Xin-Jie Guan, Min Li, Zhou Zhu, Sravan Gopalkrishnashetty Sreenivasmurthy, Senthilkumar Krishnamoorthi, Huan Zhang, Cheng-Fu Su, King-Ho Cheung, Siva Sundara Kumar Durairajan, Ju-Xian Song, Jia Liu
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 91
Background Alzheimer's disease (AD) is the most common neurodegenerative disease. Deposition of amyloid β plaques (Aβ) and neurofibrillary tangles (NFTs) is the key pathological hallmark of AD. Accumulating evidence suggest that impairment of autop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a070de7efada7e6b4fdf8c6676981328
https://pubmed.ncbi.nlm.nih.gov/34332287
https://pubmed.ncbi.nlm.nih.gov/34332287
Autor:
Yu-Xuan Kan, Cheng-Fu Su, Zhou Zhu, Jia Liu, Xin-Jie Guan, Ashok Iyaswamy, King-Ho Cheung, Yuan Zhang, Ju-Xian Song, Min Li
Publikováno v:
Longhua Chinese Medicine. 5:3-3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a35b1beaf98f8d8feec86f7253ade06
https://doi.org/10.21037/lcm-21-50
https://doi.org/10.21037/lcm-21-50
Autor:
Sravan Gopalkrishnashetty Sreenivasmurthy, Ashok Iyaswamy, Senthilkumar Krishnamoorthi, Sanjib Senapati, Sandeep Malampati, Zhou Zhu, Cheng-Fu Su, Jia Liu, Xin-Jie Guan, Benjamin Chun-Kit Tong, King-Ho Cheung, Jie-Qiong Tan, Jia-Hong Lu, Siva Sundara Kumar Durairajan, Ju-Xian Song, Min Li
Publikováno v:
Phytomedicine. 96:153887
Collective evidences have indicated that intracellular accumulation of hyperphosphorylated tau forms neurofibrillary tangles in the brain, which impairs memory, cognition and affects social activities in Alzheimer's disease (AD).To investigate the ta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a523b076420ad37f4382b52960f5f0ca
https://doi.org/10.1016/j.phymed.2021.153887
https://doi.org/10.1016/j.phymed.2021.153887