Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Xin-bo Zhou"'
Autor:
Zheng-Wei Zhang, Chun-Sheng Gao, Heng Zhang, Jian Yang, Ya-Ping Wang, Li-Bin Pan, Hang Yu, Chi-Yu He, Hai-Bin Luo, Zhen-Xiong Zhao, Xin-Bo Zhou, Yu-Li Wang, Jie Fu, Pei Han, Yu-Hui Dong, Gang Wang, Song Li, Yan Wang, Jian-Dong Jiang, Wu Zhong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 8, Pp 3298-3312 (2022)
Morinda officinalis oligosaccharides (MOO) are an oral drug approved in China for the treatment of depression in China. However, MOO is hardly absorbed so that their anti-depressant mechanism has not been elucidated. Here, we show that oral MOO acted
Externí odkaz:
https://doaj.org/article/550caaf00dce49ea8a24e4a2f2b15517
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Analgesics and sedative hypnotics in clinical use often give rise to significant side effects, particularly respiratory depression. For emergency use, specific antagonists are currently administered to counteract respiratory depression. However, anta
Externí odkaz:
https://doaj.org/article/7a75f344444545f4b90ab49215d2992f
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 71, Iss 8, Pp 883-885 (2015)
Vortioxetine, C18H22N2S, (1), systematic name 1-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazine, a new drug used to treat patients with major depressive disorder, has been crystallized as the free base and its methanol monosolvate, C18H22N2S·CH3O
Externí odkaz:
https://doaj.org/article/7588343e311a4166bbf5ce1fb3ed449d
Autor:
Feng Liu, Ning Jiang, Zhi-yong Xiao, Jun-ping Cheng, Yi-zhou Mei, Pan Zheng, Li Wang, Xiao-rui Zhang, Xin-bo Zhou, Wen-xia Zhou, Yong-xiang Zhang
Publikováno v:
PeerJ, Vol 4, p e1890 (2016)
Early studies with first-generation poly (ADP-ribose) polymerase (PARP) inhibitors have already indicated some therapeutic potential for sulfur mustard (SM) injuries. The available novel and more potential PARP inhibitors, which are undergoing clinic
Externí odkaz:
https://doaj.org/article/5f99986d0beb46d8b372397a02c75890
Publikováno v:
Molecules, Vol 21, Iss 4, p 488 (2016)
Ampakine compounds have been shown to reverse opiate-induced respiratory depression by activation of amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) glutamate receptors. However, their pharmacological exploitations are hindered by low blood
Externí odkaz:
https://doaj.org/article/003a87595a3c4d6d992d4b204968e758
Publikováno v:
World Journal of Clinical Cases. 10:7130-7137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::511b22344c9767ac7f3583023b99ab64
https://doi.org/10.12998/wjcc.v10.i20.7130
https://doi.org/10.12998/wjcc.v10.i20.7130
Autor:
Jun‐Nian Zhou, Biao Zhang, Hai‐Yang Wang, Dong‐Xing Wang, Ming‐Ming Zhang, Min Zhang, Xiao‐Kui Wang, Shi‐Yong Fan, Ying‐Chen Xu, Quan Zeng, Ya‐Li Jia, Jia‐Fei Xi, Xue Nan, Li‐Juan He, Xin‐Bo Zhou, Song Li, Wu Zhong, Wen Yue, Xue‐Tao Pei
Publikováno v:
Advanced science (Weinheim, Baden-Wurttemberg, Germany). 9(22)
Cancer stem cells (CSCs) are reported to play essential roles in chemoresistance and metastasis. Pathways regulating CSC self-renewal and proliferation, such as Hedgehog, Notch, Wnt/β-catenin, TGF-β, and Myc, may be potential therapeutic targets. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3db90b608eb3ef8907f5414cb0799e1f
https://pubmed.ncbi.nlm.nih.gov/35652264
https://pubmed.ncbi.nlm.nih.gov/35652264
Publikováno v:
Acta Crystallographica Section C Structural Chemistry. 75:545-553
Ivabradine hydrochloride (IVA-HCl) (systematic name: {[3,4-dimethoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-yl]methyl}[3-(7,8-dimethoxy-2-oxo-2,3,4,5-tetrahydro-1H-3-benzazepin-3-yl)propyl]methylazanium), is a novel medication used for the symptomatic ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cd95830179db79c1a8178e895a18ffe
https://doi.org/10.1107/s2053229619004819
https://doi.org/10.1107/s2053229619004819
Publikováno v:
Powder Diffraction. 32:78-85
Linezolid (LZD) is one of the first commercially available synthetic oxazolidinone antibiotics and is widely used for the treatment of multidrug-resistant Gram-positive bacterial infection. LZD was found to have five polymorphic forms. The most stabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38e753cb04af1976775ccb1eac9499c
https://doi.org/10.1017/s0885715617000069
https://doi.org/10.1017/s0885715617000069
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Frontiers in Pharmacology
Frontiers in Pharmacology
Analgesics and sedative hypnotics in clinical use often give rise to significant side effects, particularly respiratory depression. For emergency use, specific antagonists are currently administered to counteract respiratory depression. However, anta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50af862e7b93226520f5ad74b2ac7dd5
https://doi.org/10.3389/fphar.2019.00105
https://doi.org/10.3389/fphar.2019.00105