Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xin-Yue Cheng"'
Publikováno v:
Molecules, Vol 17, Iss 12, Pp 14565-14572 (2012)
Cadmium (Cd) is a heavy metal that poses a hazard to animal health due to its toxicity. Selenium (Se) is an important nutritional trace element. However, the potential protective effects of Se against Cd-induced toxicity remain to be elucidated. To i
Externí odkaz:
https://doaj.org/article/d94a045b430049468ceb7f363646df0a
Autor:
Qi-Xing Huang, Xin-Yue Cheng, Zhen-Chuan Mao, Yun-Sheng Wang, Li-Lin Zhao, Xia Yan, Virginia R Ferris, Ru-Mei Xu, Bing-Yan Xie
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13271 (2010)
BACKGROUND: MicroRNAs (miRNAs) are considered to be very important in regulating the growth, development, behavior and stress response in animals and plants in post-transcriptional gene regulation. Pinewood nematode, Bursaphelenchus xylophilus, is an
Externí odkaz:
https://doaj.org/article/dedc259a26924c088199d5c56280ad40
Publikováno v:
Acta Mathematica Sinica, English Series. 38:1612-1620
Autor:
Sheng Tang, Dan-Qing Song, Xin Zhang, Xin-Yue Cheng, Jian-Dong Jiang, Zong-Gen Peng, Wen-Jing Li, Ying-Hong Li
Publikováno v:
Chinese Chemical Letters. 27:1052-1057
A new series of 12-benzyl matrinic amide/ethanamide derivatives were synthesized from matrinine ( 1 ) and evaluated for their anti-HCV activity, taking compound 2 as the lead. SAR revealed that the introduction of a suitable substituent at the N ′-
Autor:
Dan-Qing Song, Hui-Qiang Wang, Lan-Ying Kong, Xin Zhang, Jian-Dong Jiang, Xin-Yue Cheng, Yu-Huan Li, Sheng Tang, Ying-Hong Li
Publikováno v:
Future Medicinal Chemistry. 8:495-508
Materials & methods: Fifty-one novel 12N-substituted matrinic acid derivatives were synthesized and evaluated for their anti-coxsackievirus B3 activities. Results: Structure–activity relationship studies revealed that the 11-side chain could be det
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(5)
12-N-Benzenesulfonyl-11-matrinic acid derivatives are a new class of anti-CVB3 compounds, but the mechanism of action is still unknown. Therein, two kinds of molecule probes were designed and constructed in this study, including matrinic amines that
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(4)
12-N-m-Cyanobenzenesulfonyl matrinic butyl methyl ether is a potent anti-coxsackievirus B3(CVB3) agent bearing a novel structure skeleton. Taking this compound as a lead, totally 15 novel target compounds have been synthesized and evaluated for t
Autor:
Feng Su, Ying-Hong Li, Xin-Yue Cheng, Chong-Wen Bi, Sheng Tang, Jian-Dong Jiang, Yu-Huan Li, Shenggang Wang, Lan-Ying Kong, Dan-Qing Song
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:3690-3693
A novel series of N-benzenesulfonyl matrinic amine/amide and matrinic methyl ether analogues were designed, synthesized and evaluated for their in vitro anti-coxsackievirus B3 (CVB3) activities. The structure-activity relationship (SAR) studies revea
Autor:
Ying-Hong Li, Xin-Yue Cheng, Lan-Ying Kong, Linlin Ma, Xin Zhang, Jian-Dong Jiang, Yu-Huan Li, Li-Mei Gao, Sheng Tang, Dan-Qing Song
Publikováno v:
ACS Medicinal Chemistry Letters. 6:183-186
Novel N-benzenesulfonyl sophocarpinic acid/ester and sophocarpinol derivatives were synthesized and evaluated for their antienteroviral activities against coxsackievirus type B3 (CVB3) from sophocarpine (1), a natural medicine isolated from Chinese h
Autor:
Dan-Qing Song, Sheng Tang, Jin-Qiu Yin, Yu-Huan Li, Ying-Hong Li, Zhan-Dong Liu, Yan-Xiang Wang, Xin-Yue Cheng
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 14(8)
Background Influenza is still a serious threat to human health with significant morbidity and mortality, so it is desirable to develop novel anti-flu drug agents with novel structures. Objective The main purpose of this research was to explore broad-