Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Xin-Wei Dong"'
Autor:
Weixi Zhang, Shui-juan Zhang, Ruijie Chen, Xin-wei Dong, Zhe Wang, Xixi Lin, Wei Zhao, Jian Shen, Xiaolei Zeng, Yong-liang Jia
Publikováno v:
Toxicology Letters. 310:61-69
PM2.5 is the main particulate air pollutant that is capable of inducing airway injury. Previous studies have indicated that Rac1 is involved in cigarette smoke-induced lung inflammation and lipopolysaccharide-mediated pulmonary injury. However, the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30202febcd33046b43d53a464b66b06a
https://doi.org/10.1016/j.toxlet.2019.04.017
https://doi.org/10.1016/j.toxlet.2019.04.017
Publikováno v:
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
BACKGROUND Obestatin, primarily recognized as a peptide within the gastrointestinal system, has been shown to benefit the cardiovascular system. We designed this experiment to study the protective role and underlying mechanism of obestatin against is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95f69e4893713c70048f9b3d564e2985
http://europepmc.org/articles/PMC5426386
http://europepmc.org/articles/PMC5426386
Autor:
Qi Liu, Ya-nan Liu, Yong-liang Jia, Qiang-min Xie, Xin-wei Dong, Wei Zhao, Jun-xia Jiang, Ling-tian Ge, Yan Guan, Yun Sun
Publikováno v:
Toxicology Letters. 273:1-9
Pulmonary fibrosis is common in a variety of inflammatory lung diseases, such as interstitial pneumonia, chronic obstructive pulmonary disease, and silicosis. There is currently no effective clinical drug treatment. It has been reported that grape se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ce0699fe72368bbeed40181023bedc
https://doi.org/10.1016/j.toxlet.2017.03.012
https://doi.org/10.1016/j.toxlet.2017.03.012
Publikováno v:
European journal of pharmacology. 848
Various studies have shown that flavones have several pharmacological activities including anti-allergy activities. However, the bioavailability of oral flavones is very low, and whether inhaled administration can improve efficacy in respiratory dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bbb96666122ed489df7418f008c9f23
https://pubmed.ncbi.nlm.nih.gov/30707957
https://pubmed.ncbi.nlm.nih.gov/30707957
Autor:
Yong-liang Jia, Xin-wei Dong, Hui-juan Shen, Yan-hong Sun, Qiang-min Xie, Ling-tian Ge, Jun-xia Jiang, Yun Sun
Publikováno v:
European Journal of Pharmacology. 761:161-167
Inhaled corticosteroid (ICS) therapy in combination with long-acting β-adrenergic agonists (LABA) is the most important treatment for allergic asthma, although the mechanism still remains unclear. However, mast cells play a central role in the patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5127fc28f55bfd822aff0cd3c439db8
https://doi.org/10.1016/j.ejphar.2015.05.008
https://doi.org/10.1016/j.ejphar.2015.05.008
Publikováno v:
Prostaglandins, Leukotrienes and Essential Fatty Acids. 94:13-19
In response to endothelial cell activation, arachidonic acid can be converted by cytochrome P450 (CYP) epoxygenases to epoxyeicosatrienoic acids (EETs), which have potent vasodilator and anti-inflammatory properties. In this study, we investigated th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5816c8668d46f76fc8813e23157acec8
https://doi.org/10.1016/j.plefa.2014.10.006
https://doi.org/10.1016/j.plefa.2014.10.006
Autor:
Yan Guan, Huahao Shen, Hui-juan Shen, Qiang-min Xie, Lin-hui Zhang, Xin-wei Dong, Jun-xia Jiang, Bo Jiang
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 122
Objectives Cigarette smoke (CS) is a major risk factor for the development of lung cancer and chronic obstructive pulmonary disease (COPD). Epithelial-mesenchymal transition (EMT) is found in invasive or metastatic phenotypes in lung cancer and COPD.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39f010c01c6dcfa18915d3c6414219d
https://pubmed.ncbi.nlm.nih.gov/30032844
https://pubmed.ncbi.nlm.nih.gov/30032844
Publikováno v:
European journal of pharmacology. 824
Salvianolic acid B (SalB) is one of the main water-soluble composites from Chinese medicine Dansen (Radix miltiorrhiza). It is used for clinical treatment of various diseases including cardiovascular, lung, Liver, renal and cancers. However, the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9b6c4c44cb4ec921e039a2969af84b
https://pubmed.ncbi.nlm.nih.gov/29382534
https://pubmed.ncbi.nlm.nih.gov/29382534
Autor:
Jun-xia Jiang, ling-tian Ge, Jian Shen, Yan Guan, Qiang-min Xie, Yun Sun, Xin-wei Dong, Yong-liang Jia, Ya-chao Jin, Bo Jiang
Publikováno v:
Toxicology. 389
Bleomycin (BLM) has potent tumor cell-killing properties that have given it an important place in cancer chemotherapy, but pulmonary toxicity is its major adverse effect. Soluble epoxide hydrolase (sEH) inhibitors have been reported to have protectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eb990bed801e838aca7fc0dad4788e8
https://pubmed.ncbi.nlm.nih.gov/28694203
https://pubmed.ncbi.nlm.nih.gov/28694203
Autor:
Qiang-min Xie, Lin-hui Zhang, Jun-xia Jiang, Jian Shen, Xiao-Feng Yan, Fenfen Li, Ximei Wu, Yan-hong Sun, Xi-xi Lin, Shui-juan Zhang, Xin-wei Dong, Hui-juan Shen, Yong-liang Jia, Yan Guan
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1840:1838-1849
Background Epithelial–mesenchymal transition (EMT) is the major pathophysiological process in lung fibrosis observed in chronic obstructive pulmonary disease (COPD) and lung cancer. Smoking is a risk factor for developing EMT, yet the mechanism rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44354d33540ba39faf448420787c0f
https://doi.org/10.1016/j.bbagen.2014.01.033
https://doi.org/10.1016/j.bbagen.2014.01.033