Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Xin-Ran Zhu"'
Autor:
Sonja Mendritzki, Saskia Schmidt, Teresa Sczepan, Xin-Ran Zhu, Daniel Segelcke, Hermann Lübbert
Publikováno v:
Parkinson's Disease, Vol 2010 (2010)
Accumulation of α-synuclein is observed in neurodegenerative diseases like Parkinson's disease and Multiple System Atrophy. In previous studies with transgenic C57BL/6 mice overexpressing α-synuclein carrying the mutations A53T and A30P found in Pa
Externí odkaz:
https://doaj.org/article/a81c9e5f933641ccb5ed9fde9182fe38
Autor:
Max Rybarski, David Mrohs, Katharina Osenberg, Maren Hemmersbach, Katharina Pfeffel, Joy Steinkamp, David Schmidt, Karina Violou, Ruth Schäning, Katja Schmidtke, Verian Bader, Michael Andriske, Pauline Bohne, Melanie D. Mark, Konstanze F. Winklhofer, Hermann Lübbert, Xin‐Ran Zhu
Publikováno v:
European Journal of Neuroscience. 57:739-761
Autor:
null Max Rybarski, null David Mrohs, null Katharina Osenberg, null Maren Hemmersbach, null Katharina Pfeffel, null Joy Steinkamp, null David Schmidt, null Karina Violou, null Ruth Schäning, null Katja Schmidtke, null Verian Bader, null Michael Andriske, null Pauline Bohne, null Melanie D. Mark, null Konstanze F. Winklhofer, null Hermann Lübbert, null Xin‐Ran Zhu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e09d9f573345efaf8fe040d5fa2447f
https://doi.org/10.1111/ejn.15917/v2/response1
https://doi.org/10.1111/ejn.15917/v2/response1
Autor:
Hermann Lübbert, Takashi Momoi, Yoshihiro Mezaki, Eriko Fujita, Yuko Tanabe, Yukiko K. Hayashi, Haruki Senoo, Xin-Ran Zhu
Publikováno v:
Cell Biology International. 37:731-736
RA175/SynCAM1/Cadm1 (Cadm1), a member of the immunoglobulin superfamily, is a synaptic cell adhesion molecule that has a PDZ-binding motif at the C-terminal region. It promotes the formation of presynaptic terminals and induces functional synapses in
Autor:
Xin-Ran Zhu, Hermann Lübbert, Onur Güntürkün, Christine C. Stichel, Christina Herold, Lyutha Maskri, Verian Bader
Publikováno v:
European Journal of Neuroscience. 26:1902-1911
Mutations in the parkin gene are the major cause of early-onset familial Parkinson’s disease (PD). We previously reported the generation and analysis of a knockout mouse carrying a deletion of exon 3 in the parkin gene. F1 hybrid pa+ ⁄‐ mice we
Autor:
Hermann Lübbert, Bettina Linnartz, Xin-Ran Zhu, Christine C. Stichel, Saskia Schmidt, Verian Bader
Publikováno v:
Human Molecular Genetics. 16:2377-2393
Mutations in the gene encoding alpha-synuclein (asyn) causes autosomal-dominant, in the parkin gene autosomal-recessive forms of Parkinson's disease (PD). The pathophysiology of PD is poorly understood, even though published evidence suggests a role
Publikováno v:
Experimental Neurology. 204:525-540
Increasing evidence of a fundamental influence of cathepsins on inflammation has drawn interest in a thorough understanding of their role in physiological and pathological processes. Even though the number of identified cathepsins has more than doubl
Autor:
Bodo Schoenebeck, Xin-Ran Zhu, Verian Bader, Beate Schmitz, Christine C. Stichel, Hermann Lübbert
Publikováno v:
Molecular and Cellular Neuroscience. 30:249-264
Serum and glucocorticoid-regulated kinase 1 (sgk1) belongs to a family of serine/threonine kinases that is under acute transcriptional control by serum and glucocorticoids. An expanding set of receptors and cellular stress pathways has been shown to
Publikováno v:
Brain Research. 1041:102-111
Recessively inherited mutations in DJ-1 have recently been linked to familial forms of parkinsonism. However, the regional and cellular expression of DJ-1 is largely unknown. In the present study, we mapped the distribution of DJ-1 transcript and pro
Autor:
Sabrina Fritzen, Xin-Ran Zhu, M. Andriske, Lyutha Maskri, Peter Engels, Christoph Ullmer, Kati Kühn, Hermann Lübbert, Christine C. Stichel
Publikováno v:
Neurodegenerative Diseases. 1:255-265
Two missense mutations (A53T and A30P) in the gene encoding the presynaptic protein α-synuclein (asyn) are associated with rare, dominantly inherited forms of Parkinson’s disease (PD) and its accumulation in Lewy bodies and Lewy neurites. As an in