SIK2 represses AKT/GSK3β/β‐catenin signaling and suppresses gastric cancer by inhibiting autophagic degradation of protein phosphatases

Autor: Xiao‐man Dai, Yan‐hui Zhang, Xiao‐han Lin, Xiao‐xing Huang, Yi Zhang, Chao‐rong Xue, Wan‐nan Chen, Jian‐xin Ye, Xin‐jian Lin, Xu Lin

Publikováno v: Molecular Oncology, Vol 15, Iss 1, Pp 228-245 (2021)

Salt‐inducible kinase 2 (SIK2) is an important regulator in various intracellular signaling pathways related to apoptosis, tumorigenesis and metastasis. However, the involvement of SIK2 in gastric tumorigenesis and the functional linkage with gastr

Externí odkaz: https://doaj.org/article/84cccf9185df4da18df326a8046eee95

Hepatitis B Virus X Protein Increases 8-Oxo-7,8-Dihydro-2ʹ-Deoxyguanosine (8-Oxodg) Level via Repressing MTH1/ MTH2 Expression in Hepatocytes

Autor: Yan-Ting Lin, Wei Liu, Yun He, Yun-Li Wu, Wan-Nan Chen, Xin-Jian Lin, Xu Lin

Publikováno v: Cellular Physiology and Biochemistry, Vol 51, Iss 1, Pp 80-96 (2018)

Background/Aims: Chronic hepatitis B virus (HBV) infection markedly increases the risk of development of hepatocellular carcinoma (HCC). Among the seven viral proteins that HBV encodes, HBV X protein (HBx) appears to have the most oncogenic potential

Externí odkaz: https://doaj.org/article/1e18f70732374f5e92e189a21f9b8d6a

Pharmacogenomics signature: A novel strategy on the individual differences in drug response

Autor: Xin-Jian Lin, Ji-Ye Yin, Xiang-Guang Meng, Zhijun Huang, Xiang Chen, Guoping Yang, Hong-Hao Zhou, Chengxian Guo, Xiaoxue Xie, Lihua Huang, Jingao Li, Jichu Wu

Publikováno v: Cancer Letters. 420:190-194

Patients exhibit a wide heterogeneity in their responses to a drug treatment due to variations in the molecular determinants underlying this heterogeneity. Pharmacogenomics approaches can be used to integrate information on drug responsiveness with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c95e3241e11f3a9cab237698a265b83b
https://doi.org/10.1016/j.canlet.2018.02.012

Effect of chemical fertilization and green manure on the abundance and community structure of ammonia oxidizers in a paddy soil

Autor: Jichen Chen, Xin-Jian Lin, Yu Fang, Ming-Kuang Wang, Zhi-Lei Yan, Fei Wang

Publikováno v: Chilean Journal of Agricultural Research, Vol 75, Iss 4, Pp 488-496 (2015)
Chilean journal of agricultural research v.75 n.4 2015
SciELO Chile
CONICYT Chile
instacron:CONICYT
Chilean journal of agricultural research, Volume: 75, Issue: 4, Pages: 488-496, Published: DEC 2015

Ammonia oxidization is a critical step in the soil N cycle and can be affected by the fertilization regimes. Chinese milk-vetch (Astragalus sinicus L., MV) is a major green manure of rice (Oryza sativa L.) fields in southern China, which is recommend

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6392df3118adc4beaf1c201e58c0dc2
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392015000500015&lng=en&tlng=en

Effects of fertilization regimes on tea yields, soil fertility, and soil microbial diversity

Autor: Li-Min Wang, Xin-Jian Lin, Shan-Lian Qiu, Dong-Feng Huang

Publikováno v: Chilean Journal of Agricultural Research, Vol 74, Iss 3, Pp 333-339 (2014)
Chilean journal of agricultural research, Volume: 74, Issue: 3, Pages: 333-339, Published: SEP 2014
Chilean journal of agricultural research v.74 n.3 2014
SciELO Chile
CONICYT Chile
instacron:CONICYT

Fertilization is an important agricultural practice for increasing crop yields and influencing soil properties. A field experiment was conducted in the period of 2006-2011 in southeastern China, to investigate the effects of fertilization regimes on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b7c042b8bab8ea56d567d414ebe92f2
http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0718-58392014000300012&lng=en&tlng=en