Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Xin ying Yang"'
Autor:
Li‐Min Wang, Pingyuan Wang, Xiao‐Min Chen, Hui Yang, Shan‐Shan Song, Zilan Song, Li Jia, Hua‐Dong Chen, Xu‐Bin Bao, Ne Guo, Xia‐Juan Huan, Yong Xi, Yan‐Yan Shen, Xin‐Ying Yang, Yi Su, Yi‐Ming Sun, Ying‐Lei Gao, Yi Chen, Jian Ding, Jing‐Yu Lang, Ze‐Hong Miao, Ao Zhang, Jin‐Xue He
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp 1-24 (2023)
Abstract Poly‐ADP‐ribose polymerase (PARP) inhibitors (PARPi) have shown great promise for treating BRCA‐deficient tumors. However, over 40% of BRCA‐deficient patients fail to respond to PARPi. Here, we report that thioparib, a next‐generat
Externí odkaz:
https://doaj.org/article/24325773452c46108ba801e5debd9f21
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
We initially described two children who developed Guillain-Barré syndrome (GBS) complicated by rhabdomyolysis (RML), and reviewed five adult patients from the literature. Through analysis of the clinical features, laboratory examination, treatment a
Externí odkaz:
https://doaj.org/article/e9cc9d179b594f6ea0852154e653dfa3
Autor:
Wei-xing Feng, Xin-ying Yang, Jiu-wei Li, Shuai Gong, Yun Wu, Wei-hua Zhang, Tong-li Han, Xiu-wei Zhuo, Chang-hong Ding, Fang Fang
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Familial hemophagocytic lymphohistiocytosis Type 2 (FHL2) associated central nervous system (CNS) involvement is less understood in children, especially when considering neurologic manifestations as part of the initial presentation. We conducted a re
Externí odkaz:
https://doaj.org/article/153472e95f5442f58d9c49ed59a09a40
Autor:
Lei Lei, Ying Xiong, Jia Chen, Jin-Bo Yang, Yi Wang, Xin-Ying Yang, Catherine C.Y. Chang, Bao-Liang Song, Ta-Yuan Chang, Bo-Liang Li
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 6, Pp 1057-1067 (2009)
High levels of the inflammatory cytokine tumor necrosis factor-α (TNF-α) are present in atherosclerotic lesions. TNF-α regulates expression of multiple genes involved in various stages of atherosclerosis, and it exhibits proatherosclerotic and ant
Externí odkaz:
https://doaj.org/article/d70dc162e2d24be39bd11630c59b3876
Autor:
Zhi-Wei Gao, Yi Chen, Bo Yuan, Yan Yan Shen, Chuan Huizi Chen, Yiming Sun, Ao Zhang, Hua-Dong Chen, Shi Yan Guo, Na Ye, Xia Juan Huan, Ze-Hong Miao, Shan Shan Song, Xin ying Yang, Jian Ding, Yi Su, Zilan Song, Yu-Ting Wang, Jin-Xue He, Yong Gan, Ying-Qing Wang, Xiao-Yan Chen
Publikováno v:
Cancer Letters. 386:47-56
Poly(ADP-ribose)polymerase (PARP)1/2 inhibitors have been proved to be clinically effective anticancer drugs. Here we report a new PARP1/2 inhibitor, simmiparib, displaying apparently improved preclinical anticancer activities relative to the first a
Autor:
Bao-Liang, Song, Can-Hua, Wang, Xiao-Min, Yao, Li, Yang, Wen-Jing, Zhang, Zhen-Zhen, Wang, Xiao-Nan, Zhao, Jin-Bo, Yang, Wei, Qi, Xin-Ying, Yang, Kenji, Inoue, Zhi-Xin, Lin, Hui-Zhan, Zhang, Tatsuhiko, Kodama, Catherine C Y, Chang, Yin-Kun, Liu, Ta-Yuan, Chang, Bo-Liang, Li
Publikováno v:
Biochemical Journal. 477:4811-4811
Humans express two ACAT (acyl-CoA:cholesterol acyltransferase) genes, ACAT1 and ACAT2. ACAT1 is ubiquitously expressed, whereas ACAT2 is primarily expressed in intestinal mucosa and plays an important role in intestinal cholesterol absorption. To inv
Publikováno v:
Antiviral Therapy. 20:583-590
Cytokines are crucial factors in the non-cytolytic antiviral process to inhibit HBV gene expression and replication. Interleukin (IL)-21 has been suggested to play an important role in HBV infection, but it remains unknown whether IL-21 can inhibit H
Autor:
Xiao Wei Hou, Li Bing Liu, Peng Fei Yang, Xin Ying Yang, Xu Zhang, Li Yang, Si Xiang Zhang, Wei Zhou
Publikováno v:
Applied Mechanics and Materials. :698-704
Odor pollution means a distinctive gas that is offensively unpleasant and harmful for the living conditions, not only disturbing social activities but also being harm for human. For the character of odor pollution, a kind of odor detecting system bas
Publikováno v:
Advanced Materials Research. :446-451
A kind of online or portable online odor detector is needed for continuously monitoring the concentration and tracing the source of the odor which is one of the atmosphere pollution. Combining gas chromatograph (GC) and micro-fluidic chip technology,
Publikováno v:
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology. 28(1)
Background/aims In patients with cirrhosis ascites, mean arterial pressure (MAP) is a credible sign of circulatory dysfunction. There are no studies on the relationship between MAP and long-term prognosis in hepatitis B virus (HBV)-related liver cirr