Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Xin Ping Xue"'
Publikováno v:
Yao xue xue bao = Acta pharmaceutica Sinica. 51(5)
The study was conducted to evaluate the pharmacokinetics of midazolam (MDZ) under different oral dosages in rats, and determine the optimum oral dosage of MDZ, a CYP3 A probe substrate in vivo. Male Sprague-Dawley rats were given a single oral dosage
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6f1b92588ae592221044a3109587208c
https://pubmed.ncbi.nlm.nih.gov/29878735
https://pubmed.ncbi.nlm.nih.gov/29878735
Publikováno v:
Phytotherapy Research. 27:1255-1259
In our previous reports, Wuzhi tablet (an herbal preparation of ethanol extract of Wuweizi (Schisandra sphenanthera)) can significantly increase the blood concentration of tacrolimus and paclitaxel in rats by inhibiting the CYP3A-mediated metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f12e0629cc216c5f50454b3685da26
https://doi.org/10.1002/ptr.4849
https://doi.org/10.1002/ptr.4849
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 55:187-193
In order to simultaneously determine in vivo P-glycoprotein (P-gp) and Cytochrome P450 3A (CYP3A) activity, a new, rapid and sensitive liquid chromatography/tandem mass spectrometry (LC-MS/MS) method has been developed and fully validated to simultan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d1a58874ffaa1a50ff6b600c6fc887
https://doi.org/10.1016/j.jpba.2011.01.018
https://doi.org/10.1016/j.jpba.2011.01.018
Autor:
Xiao Ling Qin, Xiao Chen, Ying Wang, Xin Ping Xue, Jia Li Li, Xue Ding Wang, Guo Ping Zhong, Chang Xi Wang, Hui Yang, Min Huang, Hui Chang Bi
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 42(1)
We recently reported that Wuzhi tablet (WZ; Schisandra sphenanthera extract) can inhibit P-glycoprotein (P-gp)-mediated efflux and CYP3A-mediated metabolism of tacrolimus (FK506) and thus increase the blood concentrations of FK506. Major active ligna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::885a89eac2e1df96a5627721718b6d96
https://pubmed.ncbi.nlm.nih.gov/24195812
https://pubmed.ncbi.nlm.nih.gov/24195812
Autor:
Xiao-ling Qin, Xiao Chen, Guo-ping Zhong, Xiao-mei Fan, Ying Wang, Xin-ping Xue, Min Huang, Hui-chang Bi
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 21(5)
We recently reported that Wuzhi tablet (WZ), a preparation of the ethanol extract of Wuweizi (Schisandra sphenanthera), had significant effects on blood concentrations of Tacrolimus (FK506) in renal transplant recipients and rats. The active lignans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fdd3ab9f581188aa70f263f24704010
https://pubmed.ncbi.nlm.nih.gov/24462213
https://pubmed.ncbi.nlm.nih.gov/24462213
Autor:
Xin-ping, Xue, Xiao-ling, Qin, Chenshu, Xu, Guo-ping, Zhong, Ying, Wang, Min, Huang, Hui-chang, Bi
Publikováno v:
Phytotherapy research : PTR. 27(8)
In our previous reports, Wuzhi tablet (an herbal preparation of ethanol extract of Wuweizi (Schisandra sphenanthera)) can significantly increase the blood concentration of tacrolimus and paclitaxel in rats by inhibiting the CYP3A-mediated metabolism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a3b0b99f8f032f27003a28560c01d0da
https://pubmed.ncbi.nlm.nih.gov/22996305
https://pubmed.ncbi.nlm.nih.gov/22996305
Publikováno v:
Drug metabolism and pharmacokinetics. 26(4)
The constitutive androstane receptor (CAR) is an orphan nuclear receptor which has been shown to participate in the activation of human CYP3A4, which metabolizes more than 50% of clinically used drugs. We investigated the effects of an array of compo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dd007e7c37ddbe3cc9d0f0ea903917
https://pubmed.ncbi.nlm.nih.gov/21422673
https://pubmed.ncbi.nlm.nih.gov/21422673