Zobrazeno 1 - 10
of 573
pro vyhledávání: '"Xin LUAN"'
Autor:
Xiaokun Zhang, Ye Wu, Jiayi Lin, Shengxin Lu, Xinchen Lu, Aoyu Cheng, Hongzhuan Chen, Weidong Zhang, Xin Luan
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 9, Pp 3818-3833 (2024)
Immunotherapies hold immense potential for achieving durable potency and long-term survival opportunities in cancer therapy. As vital biological mediators, peptides with high tissue penetration and superior selectivity offer significant promise for e
Externí odkaz:
https://doaj.org/article/4e96d6cb0559410681783ee1a600fbe2
Autor:
Saisai Tian, Mengting Luo, Xuyang Liao, Lijun Zhang, Jienan Zhang, Jinbo Zhang, Yanan Li, Jiangjiang Qin, Xin Luan, Weidong Zhang
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1897-1911 (2024)
Background: In recent years, mRNA-based vaccines with promising safety and functional characteristics have gained significant momentum in cancer immunotherapy. However, stable immunological molecular subtypes of lung adenocarcinoma (LUAD) and novel t
Externí odkaz:
https://doaj.org/article/0ad4602514df465891a6afa0af766a53
Autor:
Yaowei Ding, Yuxin Chen, Jialu Sun, Yijun Shi, Guoge Li, Xin Luan, Siqi Wang, Xiaotong Li, Wencan Jiang, Lijuan Wang, Guojun Zhang
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 5, Pp 1184-1196 (2024)
Abstract Objective Neuromyelitis optica (NMO) was a serious autoimmune inflammatory condition affecting the central nervous system. Currently, there was a lack of diagnostic biomarkers for AQP4‐IgG‐negative NMO patients. Methods A comparative pro
Externí odkaz:
https://doaj.org/article/bea88004957146b98cf9ad4c66b8d5b2
Autor:
Huiting Bian, Xiaohui Liang, Dong Lu, Jiayi Lin, Xinchen Lu, Jinmei Jin, Lijun Zhang, Ye Wu, Hongzhuan Chen, Weidong Zhang, Xin Luan
Publikováno v:
Advanced Science, Vol 11, Iss 26, Pp n/a-n/a (2024)
Abstract The binding of peroxisome proliferator‐activated receptor γ (PPARγ) to the orphan nuclear receptor Nur77 facilitates the ubiquitination and degradation of Nur77, and leads to aberrant fatty acid uptake for breast cancer progression. Beca
Externí odkaz:
https://doaj.org/article/d8fca0a8e304490cb2ee8883c490cb53
Autor:
Haiyang Zhou, Yiwen Shen, Guangyong Zheng, Beibei Zhang, Anqi Wang, Jing Zhang, Hao Hu, Jiayi Lin, Sanhong Liu, Xin Luan, Weidong Zhang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Mucinous colorectal adenocarcinoma (MCA) is a distinct subtype of colorectal cancer (CRC) with the most aggressive pattern, but effective treatment of MCA remains a challenge due to its vague pathological characteristics. An in‐
Externí odkaz:
https://doaj.org/article/5c2a35749e57425598d7e28d4e314ec1
Autor:
Xiaoqing Guan, Yichao Wang, Wenkai Yu, Yong Wei, Yang Lu, Enyu Dai, Xiaowu Dong, Bing Zhao, Can Hu, Li Yuan, Xin Luan, Kai Miao, Bonan Chen, Xiang‐Dong Cheng, Weidong Zhang, Jiang‐Jiang Qin
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Gastric cancer (GC) presents a formidable global health challenge, and conventional therapies face efficacy limitations. Ubiquitin‐specific protease 7 (USP7) plays pivotal roles in GC development, immune response, and chemo‐resistance, m
Externí odkaz:
https://doaj.org/article/309f94baa7be42939e0ccca5ef7af44d
Autor:
Jingjing Wan, Zhen Zhang, Chennan Wu, Saisai Tian, Yibei Zang, Ge Jin, Qingyan Sun, Pin Wang, Xin Luan, Yili Yang, Xuelin Zhan, Lingyu Linda Ye, Dayue Darrel Duan, Xia Liu, Weidong Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Reversing ventricular remodeling represents a promising treatment for the post-myocardial infarction (MI) heart failure (HF). Here, we report a novel small molecule HHQ16, an optimized derivative of astragaloside IV, which effectively revers
Externí odkaz:
https://doaj.org/article/4078760bc68a4aa7898a80e215e21b05
Autor:
Zhengang Sun, Danzhu Zhu, Hong Zhao, Jia Liu, Peng He, Xin Luan, Huiqiang Hu, Xuanfen Zhang, Gang Wei, Yongming Xi
Publikováno v:
Journal of Nanobiotechnology, Vol 21, Iss 1, Pp 1-42 (2023)
Abstract Functional hydrogels show potential application in repairing spinal cord injury (SCI) due to their unique chemical, physical, and biological properties and functions. In this comprehensive review, we present recent advance in the material de
Externí odkaz:
https://doaj.org/article/5fde091192b44ae3a6688b7503bc6eaa
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/a4ac45a6537f438b882a39636f43be5b
Autor:
Lijuan Wang, Yaowei Ding, Jie Liu, Guanghui Zheng, Siwen Li, Wencan Jiang, Kelin Chen, Xin Luan, Yuxin Chen, Siqi Wang, Guojun Zhang
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundGuillain-Barre syndrome (GBS) is an immune-mediated inflammatory peripheral neuropathy. This study aimed to conduct a systematic analysis of the serum lipids profile in GBS.MethodsWe measured the serum lipids profile in 85 GBS patients and
Externí odkaz:
https://doaj.org/article/cc648830fba043e29637efc3cf9c17a3