Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Xin‐Ming Jia"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Dimerization of C-type lectin receptors (CLRs) or Toll-like receptors (TLRs) can alter their ligand binding ability, thereby modulating immune responses. However, the possibilities and roles of dimerization between CLRs and TLRs remain uncle
Externí odkaz:
https://doaj.org/article/3e3586129bdf42b7a20043ef68f2d1fb
Publikováno v:
mLife, Vol 2, Iss 2, Pp 159-177 (2023)
Abstract Candida albicans deploys a variety of mechanisms such as morphological switch and elicitor release to promote virulence. However, the intricate interactions between the fungus and the host remain poorly understood, and a comprehensive invent
Externí odkaz:
https://doaj.org/article/8ac92785ed5641e3918f6a92294c5c8d
Autor:
Yao Yu, Rong-Rong Wang, Nai-Jun Miao, Jia-Jie Tang, Yun-Wei Zhang, Xiang-Ran Lu, Pei-Yi Yan, Jing Wang, Xin-Ming Jia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
Programmed death ligand 1 (PD-L1) suppresses host immunity during infection and microbial sepsis. Here, the authors show that PD-L1 does this by regulating the secretion of CXCL1 and CXCL2 to control neutrophil mobilization during Candida albicans in
Externí odkaz:
https://doaj.org/article/d382e9639db74f2e97245ed5feb514b7
Autor:
Ya-Nan Li, Zhong-Wei Wang, Fan Li, Ling-Hong Zhou, Yan-Shan Jiang, Yao Yu, Hui-Hui Ma, Li-Ping Zhu, Jie-Ming Qu, Xin-Ming Jia
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Cryptococcus neoformans causes opportunistic infection and potentially lethal immunopathology but therapeutic options are limited. Here the authors implicate myeloid derived suppressor cells during C. neoformans infection and suggest targeting argina
Externí odkaz:
https://doaj.org/article/308f2887e63241268784b1d1221882bd
Publikováno v:
Clinical and Translational Medicine, Vol 12, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/f5148ca4823543bd8be4e0545b590440
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
BackgroundPseudomonas aeruginosa (PA) is one of the most common Gram-negative bacteria causing hospital-acquired pulmonary infection, with high drug resistance and mortality. Therefore, it is urgent to introduce new non-antibiotic treatment strategie
Externí odkaz:
https://doaj.org/article/811ab0c363b04e9fb1c9df3bd46d8da1
Publikováno v:
Protein & Cell, Vol 8, Iss 11, Pp 856-860 (2017)
Externí odkaz:
https://doaj.org/article/be49dbef02104b1d9f19dc0bf777f152
Autor:
Xiao-Li Luo, Jian-Xiong Li, Hua-Rong Huang, Jie-Lin Duan, Ruo-Xuan Dai, Ru-Jia Tao, Ling Yang, Jia-yun Hou, Xin-Ming Jia, Jin-Fu Xu
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The incidence of Aspergillus fumigatus infection and the rate of resistance to antifungal drugs have sharply increased in recent years. LL37 has been reported as a host defense peptide with broad-spectrum antibacterial activities. However, the role o
Externí odkaz:
https://doaj.org/article/5d693e24ae214c44aec47ac1bf92afc5
Autor:
Yaojun Tong, Mei Liu, Yu Zhang, Xueting Liu, Ren Huang, Fuhang Song, Huanqin Dai, Biao Ren, Nuo Sun, Gang Pei, Jiang Bian, Xin-Ming Jia, Guanghua Huang, Xuyu Zhou, Shaojie Li, Buchang Zhang, Takashi Fukuda, Hiroshi Tomoda, Satoshi Ōmura, Richard D. Cannon, Richard Calderone, Lixin Zhang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 1, Iss 3, Pp 158-168 (2016)
Multi-drug resistance of pathogenic microorganisms is becoming a serious threat, particularly to immunocompromised populations. The high mortality of systematic fungal infections necessitates novel antifungal drugs and therapies. Unfortunately, with
Externí odkaz:
https://doaj.org/article/df7f26563eeb45d38d53ce5fed0acdbc
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cryptococcus neoformans and Cryptococcus gattii cause life-threatening meningoencephalitis or lung diseases in immunocompetent individuals or immunocompromised ones. C. neoformans and C. gattii are subdivided into five serotypes based on their capsul
Externí odkaz:
https://doaj.org/article/87d1cdaeff164a8ab52707be3e42bd7a