Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Xin'an Wu"'
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Immune checkpoint inhibitors combined chemotherapy (ICIC) are widely used for various types of lung cancer in the past decade. However, ICIC related adverse events (AEs) are more serious than immune-related adverse events (irAE) or cytoto
Externí odkaz:
https://doaj.org/article/c41e5384f392410fae64e0efda53b90e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 13, p 10839 (2023)
Renal fibrosis is relentlessly progressive and irreversible, and a life-threatening risk. With the continuous intake of a high-purine diet, hyperuricemia has become a health risk factor in addition to hyperglycemia, hypertension, and hyperlipidemia.
Externí odkaz:
https://doaj.org/article/b48176699a68436f840ed722fd8eac80
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2307 (2022)
Background: Organic anion transporter 1 (OAT1) and OAT3 have an overlapping spectrum of substrates such that one can exert a compensatory effect when the other is dysfunctional. As a result, the knockout of either OAT1 or OAT3 is not reflected in a c
Externí odkaz:
https://doaj.org/article/056a2a6f43ee4e43ba1c134667280413
Autor:
Refat, Moath, Thabit, Anes A.M., Maqboli, Abdul-Rahman, Siddick, Hesham, Al-Ghozee, Rafaʼa M., Thabet, Abdul-baqi A., Refat, Manar, Mohammed, Aiman Saleh A., Al-Sabati, Ahmed, Xin'an, Wu
Publikováno v:
In Clinical Complementary Medicine and Pharmacology December 2022 2(4)
Publikováno v:
Biological and Pharmaceutical Bulletin. 45:382-393
The organic cation transporter 2 (OCT2) belongs to the SLC22 family, while the multidrug and toxin extrusion 1 and 2-K (MATE1/MATE2-K) belong to the SLC47 family, are localized to the basolateral and apical membrane of human renal proximal tubular ep
Publikováno v:
Toxicology. 476
Anti-tuberculosis drugs-induced liver injury may be associated with the hepatic farnesoid X receptor (FXR). However, the relationship between isoniazid, rifampicin, pyrazinamide and ethambutol (HRZE) coadministration-induced liver injury and FXR has
Publikováno v:
Pharm Res
PURPOSE: The involvement of the intestinally expressed xenobiotic transporters P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP) have been implicated in rivaroxaban disposition based on in vitro studies, similar to what had previously
Autor:
Chen Shi, Zhaoming Ye, Zengwu Shao, Bifa Fan, Cibo Huang, Yuan Zhang, Xinying Kuang, Liyan Miao, Xin’an Wu, Rongsheng Zhao, Xiao Chen, Bikui Zhang, Rongsheng Tong, Xin Hu, Zhijian Fu, Jianhao Lin, Xiaomei Li, Tiezheng Sun, Guoqiang Liu, Haibin Dai, Cheng Guo, Bo Zhang, Ting Xu, Aidong Wen, Xiaocong Zuo, Jinmei Liu, Xu Chen, Huibo Li, Jing Wang, Min Luo, Tingting Fan, Yulan Qian, Xiu’mao Li, Wenjie Qiu, Xiaowen Lin, Yingchang Pang, Yunfei Hou, Difei Yao, Wen Kou, Bao Sun, Can Hu, Yanzhe Xia, Ming Zhao, Changyu Zhu, Qian Li, Yu Zhang
Publikováno v:
Journal of Clinical Medicine. 12:1544
(1) Background: Topical non-steroidal anti-inflammatory drugs (NSAIDs) are one of the primary drugs for treating musculoskeletal pain. However, there are currently no evidence-based recommendations about drug selection, drug administration, drug inte
Autor:
Jing Zhang, Jiuhong Wu, Suodi Zhai, Rongsheng Zhao, Yingchun Xu, Aidong Wen, Xianglin Zhang, Gaolin Liu, Na He, Zhiping Li, Rongsheng Tong, Wei Zhao, Zhigang Chen, Li Wang, Shan Su, Kehu Yang, Xin Hu, Wenting Zhang, Wei Zhou, Xiao Chen, Huizhi Zhang, Guanhua Du, Yang Yang, Daihong Guo, Ruichen Guo, Yalin Dong, Siyan Zhan, Yaolong Chen, Wei Lu, Xin'an Wu, Zhigang Zhao, Minggui Wang, Bikui Zhang, Bei He, Rui Wang, Fan Yang, Jieming Qu, Guang Du, Limei Zhao, Jie Zhang, Youning Liu, Jun Zhang, Zhikang Ye, Dakui Li, Yuan Lv, Huande Li, Xian-Tao Zeng, Chao Zhang, Libo Zhao, Zheng Jiao, Jian Gu, Liyan Miao, Tieying Sun, Yingyuan Zhang
Publikováno v:
Clinical Infectious Diseases. 71:S363-S371
BackgroundClinical practice guidelines or recommendations often require timely and regular updating as new evidence emerges, because this can alter the risk-benefit trade-off. The scientific process of developing and updating guidelines accompanied b
Publikováno v:
International Journal of Clinical Pharmacy. 42:1026-1035
Background Piperacillin/tazobactam, a semisynthetic antibiotic, is widely used to treat polymicrobial infections. Its hematologic adverse reactions are rare and the severity can be mild to life-threatening. To our knowledge, there has not been a publ