Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Ximian Xiao"'
Autor:
Wanlin Li, Ximian Xiao, Yuchen Qi, Xiuhui Lin, Huiqun Hu, Minqi Shi, Min Zhou, Weinan Jiang, Longqiang Liu, Kang Chen, Kai Wang, Runhui Liu
Publikováno v:
Research, Vol 6 (2023)
Host defense peptides (HDPs) are one of the potentially promising agents for infection diseases due to their broad spectrum and low resistance rate, but their clinical applications are limited by proteolytic instability, high-cost, and complicated sy
Externí odkaz:
https://doaj.org/article/208e78d1d1334cb597257644ab1a7498
Autor:
Jiayang Xie, Min Zhou, Yuxin Qian, Zihao Cong, Sheng Chen, Wenjing Zhang, Weinan Jiang, Chengzhi Dai, Ning Shao, Zhemin Ji, Jingcheng Zou, Ximian Xiao, Longqiang Liu, Minzhang Chen, Jin Li, Runhui Liu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Antibiotic resistance is a major issue in medicine and new antimicrobials for treating resistant infection are needed. Here, the authors report on antibacterial peptoid polymers, prepared via NNCA ring-opening polymerization, demonstrating antibacter
Externí odkaz:
https://doaj.org/article/5156e8b924224ead908f29cd19d0cd20
Microbial Metabolite Inspired β‐Peptide Polymers Displaying Potent and Selective Antifungal Activity
Autor:
Donghui Zhang, Chao Shi, Zihao Cong, Qi Chen, Yufang Bi, Junyu Zhang, Kaiqian Ma, Shiqi Liu, Jiawei Gu, Minzhang Chen, Ziyi Lu, Haodong Zhang, Jiayang Xie, Ximian Xiao, Longqiang Liu, Weinan Jiang, Ning Shao, Sheng Chen, Min Zhou, Xiaoyan Shao, Yidong Dai, Maoquan Li, Lixin Zhang, Runhui Liu
Publikováno v:
Advanced Science, Vol 9, Iss 14, Pp n/a-n/a (2022)
Abstract Potent and selective antifungal agents are urgently needed due to the quick increase of serious invasive fungal infections and the limited antifungal drugs available. Microbial metabolites have been a rich source of antimicrobial agents and
Externí odkaz:
https://doaj.org/article/1c5e1b59e8d8420691ee26e01b87f3fa
Autor:
Min Zhou, Jingcheng Zou, Longqiang Liu, Ximian Xiao, Shuai Deng, Yueming Wu, Jiayang Xie, Zihao Cong, Zhemin Ji, Runhui Liu
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103124- (2021)
Summary: The fascinating functions of proteins and peptides in biological systems have attracted intense interest to explore their mimics using polymers, including polypeptides synthesized from polymerization. The folding, structures and functions of
Externí odkaz:
https://doaj.org/article/59d5667766c749e885201472c26b56ea
Autor:
Natascha Hartl, Friederike Adams, Gabriella Costabile, Lorenz Isert, Markus Döblinger, Ximian Xiao, Runhui Liu, Olivia M. Merkel
Publikováno v:
Nanomaterials, Vol 9, Iss 7, p 986 (2019)
Glioblastoma multiforme is a devastating disease that has attracted enormous attention due to poor prognosis and high recurrence. Small interfering RNA (siRNA) in principle offers a promising therapeutic approach by the downregulation of disease-rela
Externí odkaz:
https://doaj.org/article/ec049bb242f242cc8816e438f41925ca
Autor:
Min Zhou, Zhemin Ji, Ximian Xiao, Longqiang Liu, Ruxin Cui, Zhengjie Luo, Zihao Cong, Runhui Liu
Publikováno v:
Polymer Chemistry. 14:1064-1071
Controllable and facile 2-oxazolines polymerization was demonstrated using TMSOTf as the initiator, which will contribute to the functional study and application of poly(2-oxazoline)s with diversified structures.
Autor:
Ning Shao, Ling Yuan, Pengcheng Ma, Min Zhou, Ximian Xiao, Zihao Cong, Yueming Wu, Guohui Xiao, Jian Fei, Runhui Liu
Publikováno v:
Journal of the American Chemical Society. 144:7283-7294
Multidrug resistance to chemotherapeutic drugs is one of the major causes for the failure of cancer treatment. Therefore, there is an urgent need to develop anticancer agents that can combat multidrug-resistant cancers effectively and mitigate drug r
Autor:
Jingcheng Zou, Min Zhou, Zhemin Ji, Ximian Xiao, Yueming Wu, Ruxin Cui, Shuai Deng, Runhui Liu
Publikováno v:
Polymer Chemistry. 13:388-394
The living and controlled copolymerization of α-NCAs and α-NNTAs enables the facile synthesis of peptide/peptoid hybrid polymers with an alternating-like distribution of residues and adjustable proteolysis by varying the proportion of peptoid resid
Autor:
Minzhang Chen, Ximian Xiao, Jiayang Xie, Wenjing Zhang, Yuxin Qian, Weinan Jiang, Sheng Chen, Jingcheng Zou, Min Zhou, Zihao Cong, Jin Li, Zhemin Ji, Runhui Liu, Longqiang Liu, Chengzhi Dai, Ning Shao
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Nature Communications
Methicillin-Resistant Staphylococcus aureus (MRSA) induced infection calls for antibacterial agents that are not prone to antimicrobial resistance. We prepare protease-resistant peptoid polymers with variable C-terminal functional groups using a ring
Publikováno v:
Chembiochem : a European journal of chemical biology.
Peptide mimics, possessing excellent biocompatibility and protease stability, have attracted broad attention and research in the biomedical field. β-Peptides and β-peptoids, as two types of vital peptide mimics, have demonstrated great potential in