Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ximena L Raffo Iraolagoitia"'
Autor:
Pooyeh Farahmand, Katarina Gyuraszova, Claire Rooney, Ximena L. Raffo-Iraolagoitia, Geeshath Jayasekera, Ann Hedley, Emma Johnson, Tatyana Chernova, Gaurav Malviya, Holly Hall, Tiziana Monteverde, Kevin Blyth, Rodger Duffin, Leo M. Carlin, David Lewis, John Le Quesne, Marion MacFarlane, Daniel J. Murphy
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Hypothesis: Asbestos-driven inflammation contributes to malignant pleural mesothelioma beyond the acquisition of rate-limiting mutations.Methods: Genetically modified conditional allelic mice that were previously shown to develop mesothelioma in the
Externí odkaz:
https://doaj.org/article/22a89dde7a66402e9f39b70b94fa6332
Autor:
Jessica M. Sierra, Florencia Secchiari, Sol Y. Nuñez, Ximena L. Raffo Iraolagoitia, Andrea Ziblat, Adrián D. Friedrich, María V. Regge, M. Cecilia Santilli, Nicolás I. Torres, Mariana Gantov, Aldana Trotta, Carlos Ameri, Gonzalo Vitagliano, Hernando Ríos Pita, Luis Rico, Agustín Rovegno, Nicolás Richards, Carolina I. Domaica, Norberto W. Zwirner, Mercedes B. Fuertes
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Natural Killer (NK) cells play a key role in cancer immunosurveillance. However, NK cells from cancer patients display an altered phenotype and impaired effector functions. In addition, evidence of a regulatory role for NK cells is emerging in divers
Externí odkaz:
https://doaj.org/article/3d8fa6bbe2054f3f9321c991e500c96a
Autor:
Osvaldo L. Podhajcer, Andrea S. Llera, Norberto W. Zwirner, Vanesa Gottifredi, Elmer A. Fernández, Alicia I. Bravo, Edgardo Salvatierra, Ximena L. Raffo Iraolagoitia, Cecilia Rotondaro, Sabrina F. Mansilla, Raúl G. Spallanzani, Cristóbal Fresno, Lorena G. Benedetti, Leandro N. Güttlein
Understanding the mechanism of metastatic dissemination is crucial for the rational design of novel therapeutics. The secreted protein acidic and rich in cysteine (SPARC) is a matricellular glycoprotein which has been extensively associated with huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ad989bffe36d56ee72976b813207ab0e
https://doi.org/10.1158/1541-7786.c.6540114.v1
https://doi.org/10.1158/1541-7786.c.6540114.v1
Autor:
Osvaldo L. Podhajcer, Andrea S. Llera, Norberto W. Zwirner, Vanesa Gottifredi, Elmer A. Fernández, Alicia I. Bravo, Edgardo Salvatierra, Ximena L. Raffo Iraolagoitia, Cecilia Rotondaro, Sabrina F. Mansilla, Raúl G. Spallanzani, Cristóbal Fresno, Lorena G. Benedetti, Leandro N. Güttlein
This file contains legends of Supplementary Figures S1-S8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b9ad1d2cd2f80e53122f5a77a442beb
https://doi.org/10.1158/1541-7786.22512063.v1
https://doi.org/10.1158/1541-7786.22512063.v1
Autor:
Osvaldo L. Podhajcer, Andrea S. Llera, Norberto W. Zwirner, Vanesa Gottifredi, Elmer A. Fernández, Alicia I. Bravo, Edgardo Salvatierra, Ximena L. Raffo Iraolagoitia, Cecilia Rotondaro, Sabrina F. Mansilla, Raúl G. Spallanzani, Cristóbal Fresno, Lorena G. Benedetti, Leandro N. Güttlein
Figure S1. Association between SPARC expression and distant metastasis free survival (RFS) in breast cancer patients with different PAM50 subtypes. Figure S2. Downregulation of SPARC expression in 4T1 and LM3 murine breast cancer cell lines. Figure S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b68ce2c94b31dc5d1781f8e0d9ace39
https://doi.org/10.1158/1541-7786.22512057
https://doi.org/10.1158/1541-7786.22512057
Autor:
Osvaldo L. Podhajcer, Andrea S. Llera, Norberto W. Zwirner, Vanesa Gottifredi, Elmer A. Fernández, Alicia I. Bravo, Edgardo Salvatierra, Ximena L. Raffo Iraolagoitia, Cecilia Rotondaro, Sabrina F. Mansilla, Raúl G. Spallanzani, Cristóbal Fresno, Lorena G. Benedetti, Leandro N. Güttlein
This file contains Supplementary Tables S1-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e2ba6b6c62fba63f7da6b9b1f257683
https://doi.org/10.1158/1541-7786.22512051.v1
https://doi.org/10.1158/1541-7786.22512051.v1
Autor:
Osvaldo L. Podhajcer, Andrea S. Llera, Norberto W. Zwirner, Vanesa Gottifredi, Elmer A. Fernández, Alicia I. Bravo, Edgardo Salvatierra, Ximena L. Raffo Iraolagoitia, Cecilia Rotondaro, Sabrina F. Mansilla, Raúl G. Spallanzani, Cristóbal Fresno, Lorena G. Benedetti, Leandro N. Güttlein
This file contains Supplementary Materials and Methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41132fb568d4ed675173a15583650764
https://doi.org/10.1158/1541-7786.22512054
https://doi.org/10.1158/1541-7786.22512054
Autor:
Jack Leslie, John B G Mackey, Thomas Jamieson, Erik Ramon-Gil, Thomas M Drake, Frédéric Fercoq, William Clark, Kathryn Gilroy, Ann Hedley, Colin Nixon, Saimir Luli, Maja Laszczewska, Roser Pinyol, Roger Esteban-Fabró, Catherine E Willoughby, Philipp K Haber, Carmen Andreu-Oller, Mohammad Rahbari, Chaofan Fan, Dominik Pfister, Shreya Raman, Niall Wilson, Miryam Müller, Amy Collins, Daniel Geh, Andrew Fuller, David McDonald, Gillian Hulme, Andrew Filby, Xabier Cortes-Lavaud, Noha-Ehssan Mohamed, Catriona A Ford, Ximena L Raffo Iraolagoitia, Amanda J McFarlane, Misti V McCain, Rachel A Ridgway, Edward W Roberts, Simon T Barry, Gerard J Graham, Mathias Heikenwälder, Helen L Reeves, Josep M Llovet, Leo M Carlin, Thomas G Bird, Owen J Sansom, Derek A Mann
Publikováno v:
Gut
Objective: Hepatocellular carcinoma (HCC) is increasingly associated with non-alcoholic steatohepatitis (NASH). HCC immunotherapy offers great promise; however, recent data suggests NASH-HCC may be less sensitive to conventional immune checkpoint inh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d39dffb99f8a95c763d022202ff9d93
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10500
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10500
Autor:
Thomas Jamieson, Ximena L. Raffo-Iraolagoitia, Sergio Lilla, Judith Secklehner, Thomas G. Bird, Daniel J. Murphy, John B. G. Mackey, Colin W. Steele, Gerard J. Graham, Amanda J. McFarlane, William T. Clarke, Leo M. Carlin, Juho Vuononvirta, Rene Jackstadt, Xabier Cortes-Lavaud, Sara Zanivan, Jim C. Norman, Frédéric Fercoq, Owen J. Sansom, Jennifer P. Morton, Katia De Filippo, Ann Hedley, Derek A. Mann, Kathryn Gilroy
Neutrophils have been implicated in poor outcomes in cancer and severe inflammation. We found that neutrophils expressing intermediate levels of Ly6G (Ly6GInt) were present in mouse cancer models and more abundant in those with high rates of spontane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a66015606ee0417065999bdd5a17324e
https://doi.org/10.1101/2021.07.21.453108
https://doi.org/10.1101/2021.07.21.453108
Autor:
Leo M. Carlin, Daniel J. Murphy, Katarina Gyuraszova, Rodger Duffin, Kevin G. Blyth, Tiziana Monteverde, Tatiana Chernova, Pooyeh Farahmand, John Le Quesne, David A. Lewis, Ximena L. Raffo-Iraolagoitia, Emma C. Johnson, Claire Rooney, Marion MacFarlane
HypothesisAsbestos-driven inflammation contributes to malignant pleural mesothelioma beyond the acquisition of rate-limiting mutations.MethodsGenetically modified conditional allelic mice that were previously shown to develop mesothelioma in the abse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f12818805160a08f3029da1f1f0d18be
https://doi.org/10.1101/2020.06.16.154815
https://doi.org/10.1101/2020.06.16.154815