Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Ximba P"'
Autor:
Kegomoditswe Malebo, Jeremy Woodward, Phindile Ximba, Qiniso Mkhize, Sanele Cingo, Thandeka Moyo-Gwete, Penny L. Moore, Anna-Lise Williamson, Rosamund Chapman
Publikováno v:
Vaccines, Vol 12, Iss 9, p 1063 (2024)
Despite treatment and other interventions, an effective prophylactic HIV vaccine is still an essential goal in the control of HIV. Inducing robust and long-lasting antibody responses is one of the main targets of an HIV vaccine. The delivery of HIV e
Externí odkaz:
https://doaj.org/article/f66ab97b60f14884ae590f25fd767ae5
Akademický článek
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Autor:
Emmanuel Margolin, Joel D. Allen, Matthew Verbeek, Michiel van Diepen, Phindile Ximba, Rosamund Chapman, Ann Meyers, Anna-Lise Williamson, Max Crispin, Edward Rybicki
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
There is an urgent need to establish large scale biopharmaceutical manufacturing capacity in Africa where the infrastructure for biologics production is severely limited. Molecular farming, whereby pharmaceuticals are produced in plants, offers a che
Externí odkaz:
https://doaj.org/article/e146390d518348fab42bc7c77ee9021a
Publikováno v:
Health SA Gesondheid: Journal of Interdisciplinary Health Sciences, Vol 26, Iss 0, Pp e1-e8 (2021)
Background: South African maternal and neonatal mortality rates remain unnecessarily high, which are considered avoidable through timeous identification, treatment and referral. An efficient referral process of high-risk pregnant women is dependent o
Externí odkaz:
https://doaj.org/article/b6e012d416d24f71a2511019fc17b241
Autor:
Phindile Ximba, Rosamund Chapman, Ann E. Meyers, Emmanuel Margolin, Michiel T. van Diepen, Anna-Lise Williamson, Edward P. Rybicki
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
HIV-1 envelope glycoprotein (Env) remains the most relevant target for the elicitation of functional antibodies to HIV by vaccination. However, soluble Env antigens often do not elicit the desired immune responses. Delivering subunit antigens on part
Externí odkaz:
https://doaj.org/article/d86c002d4a024480833e43e37108f00d
Autor:
Ros Chapman, Michiel van Diepen, Nicola Douglass, Shireen Galant, Mohamed Jaffer, Emmanuel Margolin, Phindile Ximba, Tandile Hermanus, Penny L. Moore, Anna-Lise Williamson
Publikováno v:
Vaccines, Vol 9, Iss 11, p 1281 (2021)
The modest protective effects of the RV144 HIV-1 vaccine trial have prompted the further exploration of improved poxvirus vector systems that can yield better immune responses and protection. In this study, a recombinant lumpy skin disease virus (LSD
Externí odkaz:
https://doaj.org/article/d074567c87694c7faae8bcca2f87c8b7
Autor:
Emmanuel Margolin, Rosamund Chapman, Ann E. Meyers, Michiel T. van Diepen, Phindile Ximba, Tandile Hermanus, Carol Crowther, Brandon Weber, Lynn Morris, Anna-Lise Williamson, Edward P. Rybicki
Publikováno v:
Frontiers in Plant Science, Vol 10 (2019)
The development of effective vaccines is urgently needed to curb the spread of human immunodeficiency virus type 1 (HIV-1). A major focal point of current HIV vaccine research is the production of soluble envelope (Env) glycoproteins which reproduce
Externí odkaz:
https://doaj.org/article/edbb4cb9f0f740bf9ebec41957f0a687
Autor:
Hussein K. Okoro, Olalekan S. Fatoki, Folahan A. Adekola, Bhekumusa J. Ximba, Reinette G. Snyman
Publikováno v:
Arabian Journal of Chemistry, Vol 9, Iss 1, Pp 95-104 (2016)
The spatio-temporal variation of two organotin compounds (OTCs) of tributyltin and triphenyltin in the seawater and sediment of Cape Town harbour was investigated. The organotin compounds were determined by GC-FPD following prior extraction with 0.02
Externí odkaz:
https://doaj.org/article/c05e7f965085464bbcf1686467165354
Autor:
Rosamund Chapman, Michiel van Diepen, Shireen Galant, Elizabeth Kruse, Emmanuel Margolin, Phindile Ximba, Tandile Hermanus, Penny Moore, Nicola Douglass, Anna-Lise Williamson, Edward Rybicki
Publikováno v:
Vaccines, Vol 8, Iss 1, p 54 (2020)
The HIV-1 envelope glycoprotein (Env) is present on the surface of the virion at a very low density compared to most other enveloped viruses. Substitution of various parts of the stalk domain of Env (gp41) with the corresponding elements from other v
Externí odkaz:
https://doaj.org/article/0cccae28b5a74ba797746701604ba33e
Autor:
Michiel T van Diepen, Rosamund Chapman, Penny L Moore, Emmanuel Margolin, Tandile Hermanus, Lynn Morris, Phindile Ximba, Edward P Rybicki, Anna-Lise Williamson
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0208310 (2018)
With the HIV-1 epidemic in southern Africa still rising, a prophylactic vaccine against the region's most prolific subtype (subtype C) would be a significant step forward. In this paper we report on the effect of 2 different adjuvants, AddaVax and Al
Externí odkaz:
https://doaj.org/article/83ac1399d9b04168a86ba7c1dfb269f3