Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Xilong Xiao"'
Publikováno v:
Frontiers in Veterinary Science, Vol 7 (2020)
Plant soot, as a novel feed additive, could not only improve digestive function but also adsorb mycotoxins and inhibit bacterial infections. The subchronic toxicity and prenatal developmental effects of plant soot were studied for the first time. Our
Externí odkaz:
https://doaj.org/article/2bcb698b4dd24a2bac4cf1a90c9078b5
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1010 (2020)
The precise pathogenic mechanism in Cu exposure-cause nephrotoxicity remains unclear. This study investigated the underlying molecular mechanism of copper sulfate (CuSO4)-induced nephrotoxicity. Mice were treated with CuSO4 at 50, 100, 200 mg/kg/day
Externí odkaz:
https://doaj.org/article/14b2fe721fe6489f9f30141d37bccb6f
Publikováno v:
Antioxidants, Vol 9, Iss 6, p 506 (2020)
The emergence of antimicrobial resistance in Gram-negative bacteria poses a huge health challenge. The therapeutic use of polymyxins (i.e., colistin and polymyxin B) is commonplace due to high efficacy and limiting treatment options for multidrug-res
Externí odkaz:
https://doaj.org/article/08d9f1bf58854056a7d5ab3b23a83947
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0176149 (2017)
A new compound granular premix of amoxicillin (20% w/w dry mass)/apramycin (5% w/w dry mass) was developed, and its pharmacokinetics and relative bioavailability were determined in pigs following oral administration following a cross-over study desig
Externí odkaz:
https://doaj.org/article/46ea0a0e8a1e4d8c9993d21d5c0f7899
Publikováno v:
Molecules, Vol 22, Iss 4, p 595 (2017)
Olaquindox, a feed additive, has drawn public attention due to its potential mutagenicity, genotoxicity, hepatoxicity and nephrotoxicity. The purpose of this study was to investigate the role of tuberous sclerosis complex (TSC2) pathways in olaquindo
Externí odkaz:
https://doaj.org/article/220fc5f57e2f47dd9f13a2be3dcf128e
Publikováno v:
Molecules, Vol 22, Iss 1, p 124 (2017)
Olaquindox, a quinoxaline 1,4-dioxide derivative, is widely used as a feed additive in many countries. The potential genotoxicity of olaquindox, hence, is of concern. However, the proper mechanism of toxicity was unclear. The aim of the present study
Externí odkaz:
https://doaj.org/article/3e48b47b9f5b41b689f572da493e6a70
Publikováno v:
Molecules, Vol 21, Iss 8, p 1061 (2016)
Furazolidone (FZD), a synthetic nitrofuran derivative, has been widely used as an antibacterial and antiprotozoal agent. Recently, the potential toxicity of FZD has raised concerns, but its mechanism is still unclear. This study aimed to investigate
Externí odkaz:
https://doaj.org/article/8b41a8543e33498488182d6a1890a76c
Publikováno v:
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)
Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-based Complementary and Alternative Medicine : eCAM
Fulvic acid (FA), a humic substance, has several nutraceutical properties, including anti-inflammation, antimicrobial, and immune regulation abilities. However, systematic safety assessment remains insufficient. In the present study, a battery of tox
Publikováno v:
Molecular Biology Reports. 46:1963-1972
Polymyxin is a critical antibiotic against the infection caused by multidrug-resistant gram-negative bacteria. Neurotoxicity is one of main dose-limiting factors. The present study aimed to investigate the underlying molecular mechanism on colistin i
Publikováno v:
Cell Death and Disease, Vol 9, Iss 12, Pp 1-13 (2018)
Cell Death & Disease
Cell Death & Disease
This is the first study to investigate the hepatoprotective effect of CQ on acute liver injury caused by carbon tetrachloride (CCl4) in a murine model and the underlying molecular mechanisms. Ninety-six mice were randomly divided into the control (n