Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Xijiao Ren"'
Autor:
Xijiao Ren, Rui Xue, Yan Luo, Shuang Wang, Xinyue Ge, Xuemei Yao, Liqi Li, Junxia Min, Menghuan Li, Zhong Luo, Fudi Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Radio-immunotherapy exploits the immunostimulatory features of ionizing radiation (IR) to enhance antitumor effects and offers emerging opportunities for treating invasive tumor indications such as melanoma. However, insufficient dose deposi
Externí odkaz:
https://doaj.org/article/da23f2046da746d584bd9a2a03b2c6bc
Autor:
Xijiao Ren, Zhuo Cheng, Jinming He, Xuemei Yao, Yingqi Liu, Kaiyong Cai, Menghuan Li, Yan Hu, Zhong Luo
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Immune-checkpoint inhibitors (ICI) are promising modalities for treating triple negative breast cancer (TNBC). However, hyperglycolysis, a hallmark of TNBC cells, may drive tumor-intrinsic PD-L1 glycosylation and boost regulatory T cell func
Externí odkaz:
https://doaj.org/article/20d0b31b87d7486b9d8dddcae98e8055
Publikováno v:
The Analyst. 146:2910-2918
PD-1/PD-L1 is an important pathway in immunotherapy and a high PD-L1 expression level in tumor tissues is an essential prerequisite for PD-1/PD-L1 blocking-based therapy. The PD-L1 expression level in tumor tissue sections is currently detected via i
Publikováno v:
Analytica Chimica Acta. 1185:339066
Although DNA aptamers can show comparable affinity to antibodies and have the advantage of having high batch-to-batch consistency, they often suffer from unsatisfied specificity for complex samples. The limited library size used for aptamer in vitro
Autor:
Xijiao Ren, Jiyuan Li, Na Qiao, Xinhui Lou, Jiaxing Zhao, Xiaofan Ding, Jing Li, Xiao Wu, Donglin Diao, Dihua Shangguan
Publikováno v:
Analytical chemistry. 91(21)
We report here a modified aptamer selection method, magnetic cross-linking precipitation (MCP)-SELEX, for highly efficient library enrichment and aptamer isolation. MCP-SELEX isolates bound aptamers via highly efficient chemical cross-linking between