Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Xihu Qin"'
Publikováno v:
Biology Direct, Vol 19, Iss 1, Pp 1-22 (2024)
Abstract STAM Binding Protein Like 1 (STAMBPL1), functions as a deubiquitinase (DUB) and plays a significant role in various types of cancers. However, its effect as a DUB participating in the HCC tumorigenesis and progression still unknown. In the s
Externí odkaz:
https://doaj.org/article/d9097cb07fb042f9863e5669ae8c899e
Autor:
Yuan Gao, Miao Yu, Zengyuan Liu, Yi Liu, Zhijun Kong, Chunfu Zhu, Xihu Qin, Yan Li, Liming Tang
Publikováno v:
Translational Oncology, Vol 41, Iss , Pp 101858- (2024)
ALKBH5 plays critical roles in various cellular processes via post-transcriptional regulation of oncogenes or tumor suppressors in an N6-methyladenosine (m6A)-dependent manner. However, its function in intrahepatic cholangiocarcinoma (ICC) remains un
Externí odkaz:
https://doaj.org/article/57566b3a422e42958cf438ddfd79c95c
Publikováno v:
Cancer & Metabolism, Vol 11, Iss 1, Pp 1-13 (2023)
Abstract Background Kidney renal clear cell carcinoma (KIRC) is the major histological subtype of kidney tumor which covers approximately 80% of the cases. Although various therapies have been developed, the clinical outcome remains unsatisfactory. M
Externí odkaz:
https://doaj.org/article/1ac0733d43b842728544648f7e27d1bf
Autor:
Zhihuai Wang, Peng Gao, Weijun Sun, Adeel ur Rehman, Jiakai Jiang, Suobao Xu, Cailin Xue, Chunfu Zhu, Xihu Qin
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundHepatocellular carcinoma (HCC) is one of the most frequent malignancies. Alpha-fetoprotein (AFP) has some limitations in diagnosing early HCC. Recently, long noncoding RNAs (lncRNAs) showed great potential as tumor diagnostic biomarkers, an
Externí odkaz:
https://doaj.org/article/da18b2d690ca4ab38b47dad18c39399f
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 65-81 (2021)
Isocitrate dehydrogenase (IDH) mutations increase (R)-2-hydroxyglutarate (R-2HG) production; however, functional mechanisms of R-2HG in regulating cholangiocarcinoma (CCA) development remain to be further investigated. We first applied the CRISPR-Cas
Externí odkaz:
https://doaj.org/article/2717652290ad4410902ed39d1182e716
Publikováno v:
Advances in Dermatology and Allergology, Vol 38, Iss 5, Pp 909-911 (2021)
A 57-year-old female, presented with a dark redness mass with adherent scale and unclear boundaries on the right cheek for 11 years. The patient had complained of swelling and pain of the mass for 2 months. Because of the low platelet count (40–60
Externí odkaz:
https://doaj.org/article/4c06f1f0fe17401c8c7dbe6c06ec6526
Publikováno v:
Journal of Minimal Access Surgery, Vol 17, Iss 2, Pp 197-201 (2021)
Objective: The objective of this study is to evaluate the efficacy of prophylactic active irrigation drainage in preventing post-operative pancreatic fistula (POPF) and POPF-related complications in patients undergoing limited pancreatic resection (L
Externí odkaz:
https://doaj.org/article/3ea9496d4a0f41a4a007942a3df278d2
Publikováno v:
Medicina, Vol 59, Iss 1, p 139 (2023)
Background and Objectives: Rho GTPase-activating protein (RhoGAP) is a negative regulatory element of Rho GTPases and participates in tumorigenesis. Rho GTPase-activating protein 21 (ARHGAP21) is one of the RhoGAPs and its role in cholangiocarcinoma
Externí odkaz:
https://doaj.org/article/7e3f3b253a8f41718d0b2868c4b47905
Publikováno v:
Iranian Journal of Immunology, Vol 17, Iss 1, Pp 52-63 (2020)
Background: Tim-3 has been considered as an ideal target for the immunotherapy of inflammation, but it is unclear whether Tim-3 also plays an important role in acute pancreatitis (AP), as well. Objective: To identify the immunomodulatory effects and
Externí odkaz:
https://doaj.org/article/623661ed5e9e46cba96a0bd07230683a
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe enzyme L-asparaginase (ASRGL1) catalyzes the hydrolysis of L-asparagine (Asn) to L-aspartic acid (Asp) and ammonia. Numerous studies have shown a strong correlation between ASRGL1 expression and tumorigenesis. However, the expression an
Externí odkaz:
https://doaj.org/article/4b22a7c5fdc64b6b83980e46e8395f44